Search Results - "BATES, Jason H. T"
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1
Lung tissue mechanics as an emergent phenomenon
Published in Journal of applied physiology (1985) (01-04-2011)“…The mechanical properties of lung parenchymal tissue are both elastic and dissipative, as well as being highly nonlinear. These properties cannot be fully…”
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2
The Nonallergic Asthma of Obesity: A Matter of Distal Lung Compliance
Published in American journal of respiratory and critical care medicine (15-06-2014)“…The pathogenesis of asthma in obesity is poorly understood, but may be related to breathing at low lung volumes. To determine if lung function in obese…”
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3
Modeling the impact of school reopening on SARS-CoV-2 transmission using contact structure data from Shanghai
Published in BMC public health (16-11-2020)“…Mathematical modeling studies have suggested that pre-emptive school closures alone have little overall impact on SARS-CoV-2 transmission, but reopening…”
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4
Sex-Related Differences in Pulmonary Function following 6 Months of Cigarette Exposure: Implications for Sexual Dimorphism in Mild COPD
Published in PloS one (27-10-2016)“…Female smokers have increased risk of chronic obstructive pulmonary disease (COPD) compared with male smokers who have a similar history of cigarette smoke…”
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5
Animal models of asthma
Published in American journal of physiology. Lung cellular and molecular physiology (01-09-2009)“…Studies in animal models form the basis for much of our current understanding of the pathophysiology of asthma, and are central to the preclinical development…”
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6
Modeling the influence of gravity and the mechanical properties of elastin and collagen fibers on alveolar and lung pressure–volume curves
Published in Scientific reports (19-07-2022)“…The relationship between pressure (P) and volume (V) in the human lung has been extensively studied. However, the combined effects of gravity and the…”
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7
A computational modeling approach for dosing endoscopic intratumoral chemotherapy for advanced non-small cell lung cancer
Published in Scientific reports (07-01-2022)“…We recently developed a computational model of cisplatin pharmacodynamics in an endobronchial lung tumor following ultrasound-guided transbronchial needle…”
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The effect of inhaled extrafine beclometasone dipropionate/formoterol fumarate/glycopyrronium bromide on distal and central airway indices, assessed using Functional Respiratory Imaging in COPD (DARWiIN)
Published in Respiratory research (06-10-2023)“…Abstract Background This study, in patients with symptomatic chronic obstructive pulmonary disease (COPD), explored switching therapy from non-extrafine…”
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9
Alveolar leak develops by a rich-get-richer process in ventilator-induced lung injury
Published in PloS one (28-03-2018)“…Acute respiratory distress syndrome (ARDS) is a life-threatening condition for which there are currently no medical therapies other than supportive care…”
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10
Discriminating TB lung nodules from early lung cancers using deep learning
Published in BMC medical informatics and decision making (21-06-2022)“…Abstract Background In developing countries where both high rates of smoking and endemic tuberculosis (TB) are often present, identification of early lung…”
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11
Percolation of collagen stress in a random network model of the alveolar wall
Published in Scientific reports (17-08-2021)“…Fibrotic diseases are characterized by progressive and often irreversible scarring of connective tissue in various organs, leading to substantial changes in…”
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12
Time-Controlled Adaptive Ventilation (TCAV): a personalized strategy for lung protection
Published in Respiratory research (18-01-2024)“…Acute respiratory distress syndrome (ARDS) alters the dynamics of lung inflation during mechanical ventilation. Repetitive alveolar collapse and expansion…”
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13
Analysis of Regional Mechanics in Canine Lung Injury Using Forced Oscillations and 3D Image Registration
Published in Annals of biomedical engineering (01-03-2011)“…Acute lung injury is characterized by heterogeneity of regional mechanical properties, which is thought to be correlated with disease severity. The feasibility…”
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14
Intratumoral Chemotherapy: The Effects of Drug Concentration and Dose Apportioning on Tumor Cell Injury
Published in Bioengineering (Basel) (09-08-2024)“…The addition of intravenous (i.v.) chemotherapy to i.v. immunotherapy for patients with lung cancer results in improved overall survival but is limited by…”
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15
The role of time and pressure on alveolar recruitment
Published in Journal of applied physiology (1985) (01-03-2009)“…1 SUNY Upstate Medical University, Department of Surgery, Syracuse, New York; 2 Department of Medicine, Vermont Lung Center, University of Vermont, Burlington;…”
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16
Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia
Published in Nature communications (28-09-2020)“…Early stages of the novel coronavirus disease (COVID-19) are associated with silent hypoxia and poor oxygenation despite relatively minor parenchymal…”
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17
Electric Cell-Substrate Impedance Sensing (ECIS) as a Platform for Evaluating Barrier-Function Susceptibility and Damage from Pulmonary Atelectrauma
Published in Biosensors (Basel) (01-06-2022)“…Biophysical insults that either reduce barrier function (COVID-19, smoke inhalation, aspiration, and inflammation) or increase mechanical stress (surfactant…”
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Modeling the Complex Dynamics of Derecruitment in the Lung
Published in Annals of biomedical engineering (01-11-2010)“…Recruitment maneuvers using deep inflations (DI) have long been used clinically with the objective of recruiting collapsed regions of the lung. Considerable…”
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Predicting the Mortality Benefit of CT Screening for Second Lung Cancer in a High-Risk Population
Published in PloS one (02-11-2016)“…Patients who survive an index lung cancer (ILC) after surgical resection continue to be at significant risk for a metachronous lung cancer (MLC). Indeed, this…”
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Measuring lung function in mice: the phenotyping uncertainty principle
Published in Journal of applied physiology (1985) (01-04-2003)“…Vermont Lung Center and College of Medicine, University of Vermont, Burlington, Vermont 05405 Measuring lung function in mice is essential for establishing the…”
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