Search Results - "BASTIN, M. E"

Brain white matter tract integrity as a neural foundation for general intelligence by Penke, L, Maniega, S Muñoz, Bastin, M E, Valdés Hernández, M C, Murray, C, Royle, N A, Starr, J M, Wardlaw, J M, Deary, I J

“…General intelligence is a robust predictor of important life outcomes, including educational and occupational attainment, successfully managing everyday life…”
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Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age by Karama, S, Bastin, M E, Murray, C, Royle, N A, Penke, L, Muñoz Maniega, S, Gow, A J, Corley, J, Valdés Hernández, MdelC, Lewis, J D, Rousseau, M-É, Lepage, C, Fonov, V, Collins, D L, Booth, T, Rioux, P, Sherif, T, Adalat, R, Starr, J M, Evans, A C, Wardlaw, J M, Deary, I J

“…Associations between brain cortical tissue volume and cognitive function in old age are frequently interpreted as suggesting that preservation of cortical…”
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The effects of a neuregulin 1 variant on white matter density and integrity by McIntosh, A M, Moorhead, T W J, Job, D, Lymer, G K S, Muñoz Maniega, S, McKirdy, J, Sussmann, J E D, Baig, B J, Bastin, M E, Porteous, D, Evans, K L, Johnstone, E C, Lawrie, S M, Hall, J

“…Theories of abnormal anatomical and functional connectivity in schizophrenia and bipolar disorder are supported by evidence from functional magnetic resonance…”
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Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study by Burns, J., Job, D., Bastin, M. E., Whalley, H., Macgillivray, T., Johnstone, E. C., Lawrie, S M.

“…There is growing evidence that schizophrenia is a disorder of cortical connectivity. Specifically, frontotemporal and frontoparietal connections are thought to…”
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White matter integrity and cognition in childhood and old age by DEARY, I. J, BASTIN, M. E, PATTIE, A, CLAYDEN, J. D, WHALLEY, L. J, STARR, J. M, WARDLAW, J. M

“…To test the hypothesis that white matter integrity, as measured by diffusion tensor and magnetization transfer MRI is significantly associated with cognitive…”
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Changes in NAA and lactate following ischemic stroke : A serial MR spectroscopic imaging study by MUNOZ MANIEGA, S, CVORO, V, CHAPPELL, F. M, ARMITAGE, P. A, MARSHALL, I, BASTIN, M. E, WARDLAW, J. M

“…Although much tissue damage may occur within the first few hours of ischemic stroke, the duration of tissue injury is not well defined. We assessed the…”
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Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936 by Hamilton, O. K. L., Cox, S. R., Okely, J. A., Conte, F., Ballerini, L., Bastin, M. E., Corley, J., Taylor, A. M., Page, D., Gow, A. J., Muñoz Maniega, S., Redmond, P., Valdés-Hernández, M. del C., Wardlaw, J. M., Deary, I. J.

“…Slowed processing speed is considered a hallmark feature of cognitive decline in cerebral small vessel disease (SVD); however, it is unclear whether SVD’s…”
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Neuroticism, depressive symptoms and white-matter integrity in the Lothian Birth Cohort 1936 by McIntosh, A M, Bastin, M E, Luciano, M, Maniega, S Muñoz, Del C Valdés Hernández, M, Royle, N A, Hall, J, Murray, C, Lawrie, S M, Starr, J M, Wardlaw, J M, Deary, I J

“…Clinical depression is associated with reductions in white-matter integrity in several long tracts of the brain. The extent to which these findings are…”
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MR diffusion-weighted imaging and outcome prediction after ischemic stroke by HAND, P. J, WARDLAW, J. M, RIVERS, C. S, ARMITAGE, P. A, BASTIN, M. E, LINDLEY, R. I, DENNIS, M. S

“…MR diffusion-weighted imaging (DWI) shows acute ischemic lesions early after stroke so it might improve outcome prediction and reduce sample sizes in stroke…”
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Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study by Alloza, C., Cox, S.R., Blesa Cábez, M., Redmond, P., Whalley, H.C., Ritchie, S.J., Muñoz Maniega, S., Valdés Hernández, M. del C., Tucker-Drob, E.M., Lawrie, S.M., Wardlaw, J.M., Deary, I.J., Bastin, M.E.

“…Higher polygenic risk score for schizophrenia (szPGRS) has been associated with lower cognitive function and might be a predictor of decline in brain structure…”
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Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort by Hamilton, OKL, Cox, SR, Ballerini, L, Bastin, ME, Corley, J, Gow, AJ, Muñoz Maniega, S, Redmond, P, Valdés Hernández, M del C, Wardlaw, JM, Deary, IJ

“…•Greater SVD burden associates with poorer abilities in all major cognitive domains.•SVD associates with memory and visuospatial due to covariance with general…”
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Association of white matter integrity with genetic variation in an exonic DISC1 SNP by Sprooten, E, Sussmann, J E, Moorhead, T W, Whalley, H C, ffrench-Constant, C, Blumberg, H P, Bastin, M E, Hall, J, Lawrie, S M, McIntosh, A M

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A diffusion tensor MRI study of white matter integrity in subjects at high genetic risk of schizophrenia by Muñoz Maniega, S, Lymer, G.K.S, Bastin, M.E, Marjoram, D, Job, D.E, Moorhead, T.W.J, Owens, D.G, Johnstone, E.C, McIntosh, A.M, Lawrie, S.M

“…Abstract Diffusion tensor imaging (DTI) has previously shown compromised white matter integrity in frontotemporal white matter fibers in patients with…”
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Brain age predicts mortality by Cole, J H, Ritchie, S J, Bastin, M E, Valdés Hernández, M C, Muñoz Maniega, S, Royle, N, Corley, J, Pattie, A, Harris, S E, Zhang, Q, Wray, N R, Redmond, P, Marioni, R E, Starr, J M, Cox, S R, Wardlaw, J M, Sharp, D J, Deary, I J

“…Age-associated disease and disability are placing a growing burden on society. However, ageing does not affect people uniformly. Hence, markers of the…”
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Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: The Lothian Birth Cohort 1936 by del C. Valdés Hernández, Maria, Allan, J, Glatz, A, Kyle, J, Corley, J, Brett, C. E, Muñoz Maniega, S, Royle, N. A, Bastin, M. E, Starr, J. M, Deary, I. J, Wardlaw, J. M

“…CONTEXT: Brain Iron Deposits (IDs) are associated with neurodegenerative diseases and impaired cognitive function in later life, but their cause is unknown…”
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Do acute diffusion- and perfusion-weighted MRI lesions identify final infarct volume in ischemic stroke? by RIVERS, C. S, WARDLAW, J. M, ARMITAGE, P. A, CARPENTER, T. K, CVORO, V, HAND, P. J, DENNIS, M. S

“…An acute mismatch on diffusion-weighted MRI (DWI) and perfusion-weighted MRI (PWI) may represent the "tissue-at-risk." It is unclear which "semiquantitative"…”
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Temporal evolution of water diffusion parameters is different in grey and white matter in human ischaemic stroke by Maniega, S Muñoz, Bastin, M E, Armitage, P A, Farrall, A J, Carpenter, T K, Hand, P J, Cvoro, V, Rivers, C S, Wardlaw, J M

“…Objectives: Our purpose was to investigate whether differences exist in the values and temporal evolution of mean diffusivity () and fractional anisotropy (FA)…”
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Cigarette smoking and thinning of the brain’s cortex by Karama, S, Ducharme, S, Corley, J, Chouinard-Decorte, F, Starr, J M, Wardlaw, J M, Bastin, M E, Deary, I J

“…Cigarette smoking is associated with cognitive decline and dementia, but the extent of the association between smoking and structural brain changes remains…”
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Is diffusion imaging appearance an independent predictor of outcome after ischemic stroke? by WARDLAW, J. M, KEIR, S. L, BASTIN, M. E, ARMITAGE, P. A, RANA, A. K

“…MR diffusion-weighted imaging (DWI) in ischemic stroke can be quantified by calculating the apparent diffusion coefficient (ADC) or measuring lesion volume. To…”
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Influence of thickening of the inner skull table on intracranial volume measurement in older people by Royle, N.A, Hernández, M.C. Valdés, Maniega, S. Muñoz, Arabisala, B.S, Bastin, M.E, Deary, I.J, Wardlaw, J.M

“…Abstract Introduction It is generally assumed that intracranial volume (ICV) remains constant after peaking in early adulthood. Thus ICV is used as a ‘proxy’…”
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