Search Results - "BASSO, Giuseppe"

Perceived social support and health-related quality of life in AYA cancer survivors and controls by Tremolada, Marta, Bonichini, Sabrina, Basso, Giuseppe, Pillon, Marta

“…Background This study compared education levels, health‐related quality of life (HRQoL) and perceived social support of adolescent and young adult (AYA) cancer…”
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Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ by Panciera, Tito, Azzolin, Luca, Fujimura, Atsushi, Di Biagio, Daniele, Frasson, Chiara, Bresolin, Silvia, Soligo, Sandra, Basso, Giuseppe, Bicciato, Silvio, Rosato, Antonio, Cordenonsi, Michelangelo, Piccolo, Stefano

“…The ability to induce autologous tissue-specific stem cells in culture could have a variety of applications in regenerative medicine and disease modeling. Here…”
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Glioblastoma cancer stem cells: Role of the microenvironment and therapeutic targeting by Persano, Luca, Rampazzo, Elena, Basso, Giuseppe, Viola, Giampietro

“…It has been recently suggested that many types of cancer, including glioblastoma (GBM), contain functionally subsets of cells with stem-like properties named…”
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The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells by Cordenonsi, Michelangelo, Zanconato, Francesca, Azzolin, Luca, Forcato, Mattia, Rosato, Antonio, Frasson, Chiara, Inui, Masafumi, Montagner, Marco, Parenti, Anna R., Poletti, Alessandro, Daidone, Maria Grazia, Dupont, Sirio, Basso, Giuseppe, Bicciato, Silvio, Piccolo, Stefano

“…Cancer stem cells (CSCs) are proposed to drive tumor initiation and progression. Yet, our understanding of the cellular and molecular mechanisms that underlie…”
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Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation by Fang, Celestia, Wang, Zhenjia, Han, Cuijuan, Safgren, Stephanie L, Helmin, Kathryn A, Adelman, Emmalee R, Serafin, Valentina, Basso, Giuseppe, Eagen, Kyle P, Gaspar-Maia, Alexandre, Figueroa, Maria E, Singer, Benjamin D, Ratan, Aakrosh, Ntziachristos, Panagiotis, Zang, Chongzhi

“…The three-dimensional genome organization is critical for gene regulation and can malfunction in diseases like cancer. As a key regulator of genome…”
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Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies by Roncato, Francesco, Rruga, Fatlum, Porcù, Elena, Casarin, Elisabetta, Ronca, Roberto, Maccarinelli, Federica, Realdon, Nicola, Basso, Giuseppe, Alon, Ronen, Viola, Giampietro, Morpurgo, Margherita

“…Nowadays, personalized cancer therapy relies on small molecules, monoclonal antibodies, or antibody–drug conjugates (ADC). Many nanoparticle (NP)-based drug…”
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Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000 by Möricke, Anja, Zimmermann, Martin, Valsecchi, Maria Grazia, Stanulla, Martin, Biondi, Andrea, Mann, Georg, Locatelli, Franco, Cazzaniga, Giovanni, Niggli, Felix, Aricò, Maurizio, Bartram, Claus R., Attarbaschi, Andishe, Silvestri, Daniela, Beier, Rita, Basso, Giuseppe, Ratei, Richard, Kulozik, Andreas E., Lo Nigro, Luca, Kremens, Bernhard, Greiner, Jeanette, Parasole, Rosanna, Harbott, Jochen, Caruso, Roberta, von Stackelberg, Arend, Barisone, Elena, Rössig, Claudia, Conter, Valentino, Schrappe, Martin

“…Induction therapy for childhood acute lymphoblastic leukemia (ALL) traditionally includes prednisone; yet, dexamethasone may have higher antileukemic potency,…”
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miR-34b Targets Cyclic AMP-Responsive Element Binding Protein in Acute Myeloid Leukemia by PIGAZZI, Martina, MANARA, Elena, BARON, Emma, BASSO, Giuseppe

“…The cyclic AMP-responsive element binding protein (CREB) is documented to be overexpressed in leukemia, but the underlying mechanism remains unknown. Here,…”
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Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL by Tzoneva, Gannie, Perez-Garcia, Arianne, Carpenter, Zachary, Khiabanian, Hossein, Tosello, Valeria, Allegretta, Maddalena, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Tallman, Martin S, Paganin, Maddalena, Basso, Giuseppe, Hof, Jana, Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo

“…Mutations in the cytosolic 5′-nucleotidase II gene accelerate the inactivation of chemotherapeutic nucleoside analogs in acute lymphoblastic leukemia…”
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A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells by Solito, Samantha, Falisi, Erika, Diaz-Montero, Claudia Marcela, Doni, Andrea, Pinton, Laura, Rosato, Antonio, Francescato, Samuela, Basso, Giuseppe, Zanovello, Paola, Onicescu, Georgiana, Garrett-Mayer, Elizabeth, Montero, Alberto J., Bronte, Vincenzo, Mandruzzato, Susanna

“…We recently demonstrated that human BM cells can be treated in vitro with defined growth factors to induce the rapid generation of myeloid-derived suppressor…”
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Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia by Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.

“…Although multiagent combination chemotherapy is curative in a significant fraction of childhood acute lymphoblastic leukemia (ALL) patients, 20% of cases…”
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RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation by Palanichamy, Jayanth Kumar, Tran, Tiffany M, Howard, Jonathan M, Contreras, Jorge R, Fernando, Thilini R, Sterne-Weiler, Timothy, Katzman, Sol, Toloue, Masoud, Yan, Weihong, Basso, Giuseppe, Pigazzi, Martina, Sanford, Jeremy R, Rao, Dinesh S

“…Posttranscriptional control of gene expression is important for defining both normal and pathological cellular phenotypes. In vitro, RNA-binding proteins…”
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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia by Coustan-Smith, Elaine, MS, Mullighan, Charles G, MD, Onciu, Mihaela, MD, Behm, Frederick G, Prof, Raimondi, Susana C, Prof, Pei, Deqing, MS, Cheng, Cheng, PhD, Su, Xiaoping, PhD, Rubnitz, Jeffrey E, MD, Basso, Giuseppe, Prof, Biondi, Andrea, Prof, Pui, Ching-Hon, Prof, Downing, James R, Prof, Campana, Dario, Prof

“…Summary Background About a fifth of children with acute T-lymphoblastic leukaemia (T-ALL) succumb to the disease, suggesting an unrecognised biological…”
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Direct Reversal of Glucocorticoid Resistance by AKT Inhibition in Acute Lymphoblastic Leukemia by Piovan, Erich, Yu, Jiyang, Tosello, Valeria, Herranz, Daniel, Ambesi-Impiombato, Alberto, Da Silva, Ana Carolina, Sanchez-Martin, Marta, Perez-Garcia, Arianne, Rigo, Isaura, Castillo, Mireia, Indraccolo, Stefano, Cross, Justin R., de Stanchina, Elisa, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M., Tallman, Martin S., Basso, Giuseppe, Meijerink, Jules P., Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.

“…Glucocorticoid resistance is a major driver of therapeutic failure in T cell acute lymphoblastic leukemia (T-ALL). Here, we identify the AKT1 kinase as a major…”
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Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group by HAFERLACH, Torsten, KOHLMANN, Alexander, GILKES, Amanda, CHIARETTI, Sabina, SHURTLEFF, Sheila A, KIPPS, Thomas J, RASSENTI, Laura Z, YEOH, Allen E, PAPENHAUSEN, Peter R, LIU, Wei-Min, WILLIAMS, P. Mickey, FOA, Robin, WIECZOREK, Lothar, BASSO, Giuseppe, TE KRONNIE, Geertruy, BONO, Marie-Christine, DE VOS, John, HERNINDEZ, Jesus M, HOFMANN, Wolf-Karsten, MILLS, Ken I

“…The Microarray Innovations in Leukemia study assessed the clinical utility of gene expression profiling as a single test to subtype leukemias into conventional…”
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Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000) by Schrappe, Martin, Bleckmann, Kirsten, Zimmermann, Martin, Biondi, Andrea, Möricke, Anja, Locatelli, Franco, Cario, Gunnar, Rizzari, Carmelo, Attarbaschi, Andishe, Valsecchi, Maria Grazia, Bartram, Claus R, Barisone, Elena, Niggli, Felix, Niemeyer, Charlotte, Testi, Anna Maria, Mann, Georg, Ziino, Ottavio, Schäfer, Beat, Panzer-Grümayer, Renate, Beier, Rita, Parasole, Rosanna, Göhring, Gudrun, Ludwig, Wolf-Dieter, Casale, Fiorina, Schlegel, Paul-Gerhardt, Basso, Giuseppe, Conter, Valentino

“…Purpose Delayed intensification (DI) is an integral part of treatment of childhood acute lymphoblastic leukemia (ALL), but it is associated with relevant…”
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Intratumoral Hypoxic Gradient Drives Stem Cells Distribution and MGMT Expression in Glioblastoma by Pistollato, Francesca, Abbadi, Sara, Rampazzo, Elena, Persano, Luca, Della Puppa, Alessandro, Frasson, Chiara, Sarto, Eva, Scienza, Renato, D'avella, Domenico, Basso, Giuseppe

“…Glioblastoma multiforme (GBM) are highly proliferative tumors currently treated by surgical removal, followed by radiotherapy and chemotherapy, which are…”
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LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors by Corallo, Diana, Donadon, Michael, Pantile, Marcella, Sidarovich, Viktoryia, Cocchi, Simona, Ori, Michela, De Sarlo, Miriam, Candiani, Simona, Frasson, Chiara, Distel, Martin, Quattrone, Alessandro, Zanon, Carlo, Basso, Giuseppe, Tonini, Gian Paolo, Aveic, Sanja

“…The RNA-binding protein LIN28B regulates developmental timing and determines stem cell identity by suppressing the let-7 family of microRNAs. Postembryonic…”
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The lncRNA CASC15 regulates SOX4 expression in RUNX1-rearranged acute leukemia by Fernando, Thilini R, Contreras, Jorge R, Zampini, Matteo, Rodriguez-Malave, Norma I, Alberti, Michael O, Anguiano, Jaime, Tran, Tiffany M, Palanichamy, Jayanth K, Gajeton, Jasmine, Ung, Nolan M, Aros, Cody J, Waters, Ella V, Casero, David, Basso, Giuseppe, Pigazzi, Martina, Rao, Dinesh S

“…Long non-coding RNAs (lncRNAs) play a variety of cellular roles, including regulation of transcription and translation, leading to alterations in gene…”
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Risk of Relapse of Childhood Acute Lymphoblastic Leukemia Is Predicted By Flow Cytometric Measurement of Residual Disease on Day 15 Bone Marrow by BASSO, Giuseppe, VELTRONI, Marinella, CONTER, Valentino, ARICO, Maurizio, BIONDI, Andrea, GAIPA, Giuseppe, GRAZIA VALSECCHI, Maria, DWORZAK, Michael N, RATEI, Richard, SILVESTRI, Daniela, BENETELLO, Alessandra, BULDINI, Barbara, MAGLIA, Oscar, MASERA, Giuseppe

“…Speed of blast clearance is an indicator of outcome in childhood acute lymphoblastic leukemia (ALL). Availability of measurement of minimal residual disease…”
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