Search Results - "BARTSCH, Rupert"
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Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC)
Published in Journal of neuro-oncology (01-10-2016)“…Brain metastases (BM) are frequent in small cell lung cancer (SCLC). Novel insights into their pathobiology are needed for development of better therapies. We…”
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2
Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
Published in Journal of translational medicine (12-12-2013)“…Monoclonal antibodies (mAb), such as trastuzumab are a valuable addition to breast cancer therapy. Data obtained from neoadjuvant settings revealed that…”
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3
Trastuzumab administration during pregnancy: a systematic review and meta-analysis
Published in Breast cancer research and treatment (01-01-2013)“…Landmark studies have established trastuzumab in the treatment of HER2-positive breast cancer. The present systematic review and meta-analysis aims to…”
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4
Molecularly targeted therapies in cervical cancer. A systematic review
Published in Gynecologic oncology (01-08-2012)“…Abstract Cervical cancer represents the third most common cause of female cancer mortality. Even with the best currently available treatment, a significant…”
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5
Atezolizumab plus nab-paclitaxel for unresectable, locally advanced or metastatic breast cancer: real-world results from a single academic center in Austria
Published in BMC cancer (26-10-2022)“…Abstract Purpose IMpassion130 led to the approval of atezolizumab plus nab-paclitaxel as first-line treatment for patients with unresectable locally advanced…”
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6
Diffusion-weighted MRI of breast lesions: a prospective clinical investigation of the quantitative imaging biomarker characteristics of reproducibility, repeatability, and diagnostic accuracy
Published in NMR in biomedicine (01-10-2016)“…Diffusion‐weighted MRI (DWI) provides insights into tissue microstructure by visualization and quantification of water diffusivity. Quantitative evaluation of…”
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7
Monocyte subsets in breast cancer patients under treatment with aromatase inhibitor and mucin-1 cancer vaccine
Published in Journal of translational medicine (08-10-2024)“…Monocytes comprise subsets of classical, intermediate and non-classical monocytes with distinct anti- or pro-tumor effects in breast cancer (BC). They are…”
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8
Emergence of immune-related adverse events correlates with pathological complete response in patients receiving pembrolizumab for early triple-negative breast cancer
Published in Oncoimmunology (31-12-2023)“…Based upon results of the KEYNOTE-522 trial and following approval by regulatory authorities, the addition of pembrolizumab to chemotherapy is now the…”
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9
Differential immunomodulatory effects of epirubicin/cyclophosphamide and docetaxel in breast cancer patients
Published in Journal of experimental & clinical cancer research (14-11-2023)“…Abstract Background Epirubicin/cyclophosphamide (EC) and docetaxel (D) are commonly used in a sequential regimen in the neoadjuvant treatment of early,…”
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10
Adverse Events of Trastuzumab Emtansine (T-DM1) in the Treatment of HER2-Positive Breast Cancer Patients
Published in Breast care (Basel, Switzerland) (01-12-2017)“…The human epidermal growth factor receptor 2 (HER2) is commonly associated with poor prognosis and is overexpressed in approximately 15-20% of all breast…”
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Expected Medium- and Long-Term Impact of the COVID-19 Outbreak in Oncology
Published in JCO global oncology (01-12-2021)“…The COVID-19 pandemic has affected healthcare systems globally, leading to reorganization of medical activities. We performed an international survey aimed to…”
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mTOR inhibitors in breast cancer: A systematic review
Published in Gynecologic oncology (01-12-2012)“…Abstract PI3K/AKT/mTOR pathway is a crucial mediator of tumor progression. As the PI3K/Akt pathway is heavily deregulated in breast cancer, the application of…”
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13
Tamoxifen and Anastrozole As a Sequencing Strategy: A Randomized Controlled Trial in Postmenopausal Patients With Endocrine-Responsive Early Breast Cancer From the Austrian Breast and Colorectal Cancer Study Group
Published in Journal of clinical oncology (01-03-2012)“…Anastrozole (ANA) alone delivers significant disease-free survival benefits over tamoxifen (TAM) monotherapy in postmenopausal women with early estrogen…”
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14
Prevalence and biopsychosocial indicators of fatigue in cancer patients
Published in Cancer medicine (Malden, MA) (01-06-2024)“…Introduction Symptoms of cancer‐related fatigue (CRF) can have a significant impact on patients' quality of life and treatment adherence. We aimed to…”
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15
Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial)
Published in BMC cancer (06-11-2018)“…Triple-negative breast cancer (TNBC) comprises a heterogeneous group of diseases which are generally associated with poor prognosis. Up to now, no targeted…”
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16
Efficacy and safety of everolimus plus exemestane in patients with HR+, HER2− advanced breast cancer progressing on/after prior endocrine therapy in routine clinical practice: Primary results from the non-interventional study, STEPAUT
Published in Breast (Edinburgh) (01-04-2020)“…STEPAUT, an Austrian non-interventional study, evaluated the safety and efficacy of everolimus plus exemestane in patients with hormone receptor-positive…”
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17
Capecitabine and Trastuzumab in Heavily Pretreated Metastatic Breast Cancer
Published in Journal of clinical oncology (01-09-2007)“…In human epidermal growth factor 2 (HER-2)-positive advanced breast cancer, taxanes or vinorelbine plus trastuzumab are among the most widely applied options…”
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18
Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients
Published in Breast (Edinburgh) (01-10-2014)“…Abstract Background Recently, HER3-expression was postulated as independent risk factor for metastatic spread. Therefore, we investigated the role of HER3…”
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The role of ADAMTS‐13 and von Willebrand factor in cancer patients: Results from the Vienna Cancer and Thrombosis Study
Published in Research and practice in thrombosis and haemostasis (01-07-2019)“…Unlabelled Box Cancer‐associated venous thromboembolism (VTE) is an important complication in the course of a malignant disease. Low ADAMTS‐13 (a…”
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The cancer survival index—A prognostic score integrating psychosocial and biological factors in patients diagnosed with cancer or haematologic malignancies
Published in Cancer medicine (Malden, MA) (01-09-2022)“…Objective We aimed to investigate whether (1) psychological and social indicators influence survival in patients diagnosed with cancer or haematologic…”
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