Search Results - "BARTLETT, DAVID B"
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High-Intensity Interval Training for Cardiometabolic Disease Prevention
Published in Medicine and science in sports and exercise (01-06-2019)“…PURPOSEThe 2018 Physical Activity Guidelines Advisory Committee systematically searched existing literature reviews to assess the relationship between…”
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Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study
Published in Arthritis research & therapy (14-06-2018)“…Rheumatoid arthritis (RA) is a chronic inflammatory disease in which adults have significant joint issues leading to poor health. Poor health is compounded by…”
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Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis
Published in Arthritis research & therapy (10-07-2021)“…Exercise training, including high-intensity interval training (HIIT), improves rheumatoid arthritis (RA) inflammatory disease activity via unclear mechanisms…”
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A pilot study to assess the feasibility of a remotely monitored high-intensity interval training program prior to allogeneic hematopoietic stem cell transplantation
Published in PloS one (30-11-2023)“…Although allogeneic hematopoietic stem cell transplantation (HCT) can be a curative therapy for hematologic disorders, it is associated with treatment-related…”
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A pilot study of high-intensity interval training in older adults with treatment naïve chronic lymphocytic leukemia
Published in Scientific reports (30-11-2021)“…Chronic lymphocytic leukemia (CLL) is the most common leukemia in the USA, affecting predominantly older adults. CLL is characterized by low physical fitness,…”
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Impact of exercise on the immune system and outcomes in hematologic malignancies
Published in Blood advances (28-04-2020)“…Exercise is increasingly recognized as important to cancer care. The biology of how exercise improves outcomes is not well understood, however. Studies show…”
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Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness
Published in Scientific reports (06-05-2022)“…Rheumatoid arthritis (RA) T cells drive autoimmune features via metabolic reprogramming that reduces oxidative metabolism. Exercise training improves…”
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Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes
Published in Arthritis research & therapy (27-12-2018)“…Sarcopenic obesity, associated with greater risk of cardiovascular disease (CVD) and mortality in rheumatoid arthritis (RA), may be related to dysregulated…”
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Autophagy as a Therapeutic Target to Enhance Aged Muscle Regeneration
Published in Cells (Basel, Switzerland) (20-02-2019)“…Skeletal muscle has remarkable regenerative capacity, relying on precise coordination between resident muscle stem cells (satellite cells) and the immune…”
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Rejuvenation of Neutrophil Functions in Association With Reduced Diabetes Risk Following Ten Weeks of Low-Volume High Intensity Interval Walking in Older Adults With Prediabetes - A Pilot Study
Published in Frontiers in immunology (05-05-2020)“…Neutrophil dysfunction is a common feature of aging, and is associated with the pathogenesis of many age-related diseases, including type 2 diabetes mellitus…”
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Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low-Volume High-Intensity Interval or Moderate-Intensity Continuous Training in Sedentary Adults
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Neutrophils and monocytes are key components of the innate immune system that undergo age-associated declines in function. This study compared the impact of…”
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Associations of clinical and circulating metabolic biomarkers with low physical fitness and function in adults with chronic lymphocytic leukemia
Published in Frontiers in oncology (03-08-2022)“…Many patients with chronic lymphocytic leukemia (CLL) experience physical dysfunction and low overall fitness. It remains unknown what factors drive CLL…”
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The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors
Published in Frontiers in immunology (27-10-2021)“…Following therapy, breast cancer survivors (BCS) have an increased risk of infections because of age and cancer dysregulation of inflammation and neutrophil…”
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A Pilot Study of Home-Based Exercise and Personalized Nutrition Counseling Intervention in Endometrial Cancer Survivors
Published in Frontiers in oncology (11-06-2021)“…To assess the feasibility of a home-based aerobic exercise and nutrition counseling intervention and effect on cardiorespiratory fitness, cardiovascular…”
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Acute exercise induces distinct quantitative and phenotypical T cell profiles in men with prostate cancer
Published in Frontiers in sports and active living (30-05-2023)“…Reduced testosterone levels can influence immune system function, particularly T cells. Exercise during cancer reduces treatment-related side effects and…”
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Physiological Fitness and the Pathophysiology of Chronic Lymphocytic Leukemia (CLL)
Published in Cells (Basel, Switzerland) (11-05-2021)“…Chronic lymphocytic leukemia (CLL) is associated with physical dysfunction and low overall fitness that predicts poor survival following the commencement of…”
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Mucosal-Associated Invariant T Cell Response to Acute Exercise and Exercise Training in Older Obese Women
Published in Sports (Basel) (24-09-2021)“…(1) Background: Obesity is a major global public health concern as it is associated with many of the leading causes of preventable deaths. Exercise reduces…”
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Exercise-induced modulation of monocytes in breast cancer survivors
Published in Brain, behavior, & immunity. Health (01-07-2021)“…Exercise training reduces inflammation in breast cancer survivors; however, the mechanism is not fully understood. The effects of acute and chronic exercise on…”
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Multisystem physiological perspective of human frailty and its modulation by physical activity
Published in Physiological reviews (01-04-2023)“…"Frailty" is a term used to refer to a state characterized by enhanced vulnerability to, and impaired recovery from, stressors compared with a nonfrail state,…”
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Moderate physical activity associated with a higher naïve/memory T-cell ratio in healthy old individuals: potential role of IL15
Published in Age and ageing (27-04-2020)“…Abstract Introduction ageing is accompanied by impairments in immune responses due to remodelling of the immune system (immunesenescence). Additionally, a…”
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