Search Results - "BARTLETT, D. L"
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RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer
Published in Cell death & disease (23-10-2014)“…A hypoxic tumor microenvironment is characteristic of many cancer types, including one of the most lethal, pancreatic cancer. We recently demonstrated that the…”
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2
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer
Published in Cell death & disease (30-10-2014)“…Unresectable colorectal liver metastases remain a major unresolved issue and more effective novel regimens are urgently needed. While screening synergistic…”
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3
Oncolytic viruses as platform for multimodal cancer therapeutics: a promising land
Published in Cancer gene therapy (01-07-2014)Get full text
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4
The combination of immunosuppression and carrier cells significantly enhances the efficacy of oncolytic poxvirus in the pre-immunized host
Published in Gene therapy (01-12-2010)“…Pre-existing antipoxvirus immunity in cancer patients presents a severe barrier to poxvirus-mediated oncolytic virotherapy. We have explored strategies of…”
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5
TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal cancer
Published in Gene therapy (01-04-2010)“…We have explored a unique combination therapy for metastatic colorectal cancer. This strategy combines a potent and new oncolytic poxvirus expressing a…”
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6
Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
Published in Journal of clinical oncology (01-04-1998)“…To evaluate the efficacy and systemic and regional toxicities of hyperthermic isolated hepatic perfusion (IHP) using tumor necrosis factor (TNF) and melphalan…”
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7
Forty-eight-hour fast : The diagnostic test for insulinoma
Published in The journal of clinical endocrinology and metabolism (01-09-2000)“…Insulinoma causes fasting hypoglycemia due to inappropriate insulin secretion. Its diagnosis is based on demonstrating Whipple's triad during a supervised 72-h…”
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8
Long-term results after resection for gallbladder cancer : Implications for staging and management
Published in Annals of surgery (01-11-1996)“…The surgical management of gallbladder cancer is controversial. There is no consensus among surgeons as to the indications for reoperation or radical…”
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9
Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression
Published in Gene therapy (01-07-2000)“…Replicating viruses for cancer gene therapy have beneficial antitumor effects, however, in the setting of an enzyme/prodrug system, the interactions between…”
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10
A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virus
Published in Gene therapy (01-04-2007)“…To enhance further the safety and efficacy of oncolytic vaccinia virus, we have developed a new virus with targeted deletions of three viral genes encoding…”
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11
A Phase I-II Study of Isolated Hepatic Perfusion Using Melphalan with or without Tumor Necrosis Factor for Patients with Ocular Melanoma Metastatic to Liver
Published in Clinical cancer research (01-08-2000)“…There are no satisfactory treatment options for patients with ocular melanoma metastatic to liver, and after liver metastases are identified, median survival…”
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12
Tumor-specific gene delivery using recombinant vaccinia virus in a rabbit model of liver metastases
Published in JNCI : Journal of the National Cancer Institute (20-10-1999)“…Several approaches to gene therapy for cancer have yielded promising results in rodent models. The translation of these results to the clinical realm has been…”
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13
Cytoreductive surgery and HIPEC improve survival compared to palliative chemotherapy for biliary carcinoma with peritoneal metastasis: A multi-institutional cohort from PSOGI and BIG RENAPE groups
Published in European journal of surgical oncology (01-09-2018)“…Peritoneal metastasis from biliary carcinoma (PMC) is associated with poor prognosis when treated with chemotherapy. To evaluate the impact on survival of…”
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14
Systemic administration of a recombinant vaccinia virus expressing the cytosine deaminase gene and subsequent treatment with 5-fluorocytosine leads to tumor-specific gene expression and prolongation of survival in mice
Published in Cancer research (Chicago, Ill.) (15-07-1999)“…Suicide gene therapy using the cytosine deaminase (CD) gene and 5-fluorocytosine (5-FC) has shown promising results for the treatment of colon carcinoma cells…”
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15
Yaba-Like Disease Virus: an Alternative Replicating Poxvirus Vector for Cancer Gene Therapy
Published in Journal of Virology (01-11-2001)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Inhibitors of C5 complement enhance vaccinia virus oncolysis
Published in Cancer gene therapy (01-06-2013)“…Genetically engineered tumor-selective vaccinia virus (VV) has been demonstrated to be a highly effective oncolytic agent, but immune clearance may limit its…”
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17
Development of a tetracycline-inducible system for regulation of oncolytic vaccinia virus gene expression
Published in Annals of surgical oncology (01-02-2004)Get full text
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18
A Phase I trial of continuous hyperthermic peritoneal perfusion with tumor necrosis factor and cisplatin in the treatment of peritoneal carcinomatosis
Published in Cancer (15-09-1998)“…BACKGROUND Tumor necrosis factor (TNF), hyperthermia, and cisplatin have synergistic cytotoxicity against cancer cells in vitro. This combination may be well…”
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Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics
Published in Cancer (01-12-1997)“…BACKGROUND This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated limb perfusion (ILP)…”
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20
A Phase I Trial of Isolated Hepatic Perfusion (IHP) Using 5-FU and Oxaliplatin in Patients with Unresectable Isolated Liver Metastases from Colorectal Cancer
Published in Annals of surgical oncology (01-07-2013)“…Background Isolated hepatic perfusion (IHP) with melphalan is an established approach for patients with unresectable metastatic liver lesions. This study…”
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