Search Results - "BARTHELMEBS, Mariette"

The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma by Hamaidi, Imène, Coquard, Catherine, Danilin, Sabrina, Dormoy, Valérian, Béraud, Claire, Rothhut, Sylvie, Barthelmebs, Mariette, Benkirane-Jessel, Nadia, Lindner, Véronique, Lang, Hervé, Massfelder, Thierry

“…Metastatic clear cell renal cell carcinoma (CCC) remains incurable despite advances in the development of anti-angiogenic targeted therapies and the emergence…”
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Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma by DORMOY, Valerian, BERAUD, Claire, LINDNER, Véronique, COQUARD, Catherine, BARTHELMEBS, Mariette, BRASSE, David, JACQMIN, Didier, LANG, Hervé, MASSFELDER, Thierry

“…Human clear cell renal cell carcinoma (CCC) remains resistant to treatments despite the progress in targeted therapies. Several signaling pathways acting…”
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Parathyroid Hormone-Related Protein Is a Mitogenic and a Survival Factor of Mesangial Cells from Male Mice: Role of Intracrine and Paracrine Pathways by Hochane, Mazène, Raison, Denis, Coquard, Catherine, Imhoff, Olivier, Massfelder, Thierry, Moulin, Bruno, Helwig, Jean-Jacques, Barthelmebs, Mariette

“…Glomerulonephritis is characterized by the proliferation and apoptosis of mesangial cells (MC). The parathyroid-hormone related protein (PTHrP) is a locally…”
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Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene by MASSFELDER, Thierry, LANG, Herve, SCHORDAN, Eric, LINDNER, Veronique, ROTHHUT, Sylvie, WELSCH, Sandra, SIMON-ASSMANN, Patricia, BARTHELMEBS, Mariette, JACQMIN, Didier, HELWIG, Jean-Jacques

“…Clear cell renal carcinoma (CCRC) is responsible for 2% of cancer-related deaths worldwide and is resistant to virtually all therapies, indicating the…”
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Effects of dietary salt changes on renal renin-angiotensin system in rats by Ingert, Catherine, Grima, Michèle, Coquard, Catherine, Barthelmebs, Mariette, Imbs, Jean-Louis

“…Renin (RA) and angiotensin-converting enzyme (ACE) activities and angiotensinogen, ANG I, and ANG II levels were measured in the kidney (cortex and medulla)…”
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Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats by Ingert, Catherine, Grima, Michèle, Coquard, Catherine, Barthelmebs, Mariette, Imbs, Jean-Louis

“…This study was designed to determine the involvement of AT(1) receptors in the uptake of ANG II in the kidney of rats exposed to differing salt intake. Male…”
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Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats by RAHMOUNI, Kamal, BARTHELMEBS, Mariette, GRIMA, Michèle, IMBS, Jean-Louis, DE JONG, Wybren

“…We recently showed that brain mineralocorticoid receptors (MRs) are involved in blood pressure and kidney function control in normotensive Wistar rats. We now…”
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Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA–salt hypertension by Rahmouni, Kamal, Sibug, Rosana M., De Kloet, E.Ronald, Barthelmebs, Mariette, Grima, Michèle, Imbs, Jean-Louis, De Jong, Wybren

“…In normotensive rats, we have previously demonstrated a role of brain mineralocorticoid receptors in blood pressure and renal function control. In the present…”
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Type 1 parathyroid hormone receptor expression level modulates renal tone and plasma renin activity in spontaneously hypertensive rat by MASSFELDER, Thierry, TAESCH, Nathalie, FRITSCH, Samuel, EICHINGER, Anne, BARTHELMEBS, Mariette, STEWART, Andrew F, HELWIG, Jean-Jacques

“…These studies examine whether PTHrP(1-36), a vasodilator, modulates BP and renal vascular resistance (RVR) in spontaneously hypertensive rat (SHR). Within the…”
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Role of shear stress in nitric oxide‐dependent modulation of renal angiotensin II vasoconstriction by Endlich, Karlhans, Muller, Catherine, Barthelmebs, Mariette, Helwig, Jean‐Jacques

“…Renal vasoconstriction in response to angiotensin II (ANGII) is known to be modulated by nitric oxide (NO). Since shear stress stimulates the release of a…”
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Parathyroid hormone-related protein modulates inflammation in mouse mesangial cells and blunts apoptosis by enhancing COX-2 expression by Hochane, Mazène, Raison, Denis, Coquard, Catherine, Béraud, Claire, Bethry, Audrey, Danilin, Sabrina, Massfelder, Thierry, Barthelmebs, Mariette

“…Injury of mesangial cells (MC) is a prominent feature of glomerulonephritis. Activated MC secrete inflammatory mediators that induce cell apoptosis…”
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Parathyroid Hormone–Related Protein Contributes to Early Healing of Habu Snake Venom–Induced Glomerulonephritis in Mice by Hochane, Mazène, Raison, Denis, Coquard, Catherine, Béraud, Claire, Danilin, Sabrina, Bethry, Audrey, Massfelder, Thierry, Barthelmebs, Mariette

“…Proliferative glomerulonephritis is characterized by local inflammation and mesangial cell deterioration, followed by mesangial proliferation and glomerular…”
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Targeting FAK scaffold functions inhibits human renal cell carcinoma growth by Béraud, Claire, Dormoy, Valérian, Danilin, Sabrina, Lindner, Véronique, Béthry, Audrey, Hochane, Mazène, Coquard, Catherine, Barthelmebs, Mariette, Jacqmin, Didier, Lang, Hervé, Massfelder, Thierry

“…Human conventional renal cell carcinoma (CCC) remains resistant to current therapies. Focal Adhesion Kinase (FAK) is upregulated in many epithelial tumors and…”
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Vascular kinin B1 and B2 receptor‐mediated effects in the rat isolated perfused kidney–differential regulations by Bagaté, Karim, Develioglu, Leyla, Imbs, Jean‐Louis, Michel, Bruno, Helwig, Jean‐Jacques, Barthelmebs, Mariette

“…Bradykinin (BK) and analogs acting preferentially at kinin B1 or B2 receptors were tested on the rat isolated perfused kidney. Kidneys were perfused in an open…”
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MP60-09 LIM1 ONCOGENE AS A NEW THERAPEUTIC TARGET IN ADVANCED HUMAN RENAL CELL CARCINOMA by Hamaidi, Imène, Danilin, Sabrina, Dormoy, Valérian, Rothhut, Sylvie, Coquard, Catherine, Béraud, Claire, Barthelmebs, Mariette, Lindner, Véronique, Lang, Hervé, Massfelder, Thierry

“…Clear cell renal cell carcinoma (CCC) is resistant to therapies. We and others have shown the oncogenicity of various signaling pathways/markers including the…”
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Knockdown of parathyroid hormone related protein in smooth muscle cells alters renal hemodynamics but not blood pressure by Raison, Denis, Coquard, Catherine, Hochane, Mazène, Steger, Jacques, Massfelder, Thierry, Moulin, Bruno, Karaplis, Andrew C, Metzger, Daniel, Chambon, Pierre, Helwig, Jean-Jacques, Barthelmebs, Mariette

“…Parathyroid hormone-related protein (PTHrP) belongs to vasoactive factors that regulate blood pressure and renal hemodynamics both by reducing vascular tone…”
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Plasma renin activity and changes in tissue angiotensin converting enzyme by Michel, B, Grima, M, Stephan, D, Coquard, C, Welsch, C, Barthelmebs, M, Imbs, J L

“…Recent evidence suggests that tissue generation of angiotensins I and II depends on the level of the plasma components of the renin-angiotensin system and on…”
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AT 2 ‐antagonist sensitive potentiation of angiotensin II‐induced vasoconstrictions by blockade of nitric oxide synthesis in rat renal vasculature by Muller, Catherine, Endlich, Karlhans, Barthelmebs, Mariette, Helwig, Jean‐Jacques

“…Although the actions of angiotensin II (Ang II) on renal haemodynamics appear to be mediated by activation of the AT 1 receptor subtype, AT 2 binding sites…”
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Pathophysiological Role of Dopamine in the Kidney: Effects in Diabetes Mellitus and after Contralateral Nephrectomy by Barthelmebs, Mariette, Mayer, Philippe, Thomas, Anne, Grima, Michèle, Imbs, Jean-Louis

“…Both insulin-dependent diabetes mellitus (IDDM) and unilateral nephectomy (UNX) are associated with an increase in the glomerular filtration rate. Glomerular…”
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Vascular kinin B 1 and B 2 receptor‐mediated effects in the rat isolated perfused kidney–differential regulations by Bagaté, Karim, Develioglu, Leyla, Imbs, Jean‐Louis, Michel, Bruno, Helwig, Jean‐Jacques, Barthelmebs, Mariette

“…Bradykinin (BK) and analogs acting preferentially at kinin B 1 or B 2 receptors were tested on the rat isolated perfused kidney. Kidneys were perfused in an…”
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