Search Results - "BARTELS, Douglas J"

Quorum Sensing in Staphylococcus aureus Biofilms by YARWOOD, Jeremy M, BARTELS, Douglas J, VOLPER, Esther M, GREENBERG, E. Peter

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Dual Targeting of GyrB and ParE by a Novel Aminobenzimidazole Class of Antibacterial Compounds by GROSSMAN, Trudy H, BARTELS, Douglas J, MANI, Nagraj, MULLIN, Steve, GROSS, Christian H, PARSONS, Jonathan D, YUSHENG LIAO, GRILLOT, Anne-Laure, STAMOS, Dean, OLSON, Eric R, CHARIFSON, Paul S

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Genome Editing in Ferret Airway Epithelia Mediated by CRISPR/Nucleases Delivered with Amphiphilic Shuttle Peptides by Luo, Meihui, Ma, Jia, Cheng, Xue, Wu, Shuang, Bartels, Douglas J, Guay, David, Engelhardt, John F, Liu, Xiaoming

“…Gene editing strategies are attractive for treating genetic pulmonary diseases such as cystic fibrosis (CF). However, challenges have included the development…”
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Palmitoylation and Plasma Membrane Localization of Ras2p by a Nonclassical Trafficking Pathway in Saccharomyces cerevisiae by Dong, Xiangwen, Mitchell, David A., Lobo, Sandra, Zhao, Lihong, Bartels, Douglas J., Deschenes, Robert J.

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Characterization of telaprevir treatment outcomes and resistance in patients with prior treatment failure: Results from the REALIZE trial by De Meyer, Sandra, Dierynck, Inge, Ghys, Anne, Beumont, Maria, Daems, Bjorn, Van Baelen, Ben, Sullivan, James C., Bartels, Douglas J., Kieffer, Tara L., Zeuzem, Stefan, Picchio, Gaston

“…In the Phase 3 REALIZE study, 662 genotype 1 hepatitis C virus (HCV)‐infected patients with prior peginterferon/ribavirin treatment failure (including…”
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In utero and postnatal ivacaftor/lumacaftor therapy rescues multiorgan disease in CFTR-F508del ferrets by Evans, Idil Apak, Sun, Xingshen, Liang, Bo, Vegter, Amber R, Guo, Lydia, Lynch, Thomas J, Zhang, Yan, Zhang, Yulong, Yi, Yaling, Yang, Yu, Feng, Zehua, Park, Soo Yeun, Shonka, Amanita, McCumber, Hannah, Qi, Lisi, Wu, Peipei, Liu, Guangming, Lacina, Allison, Wang, Kai, Gibson-Corley, Katherine N, Meyerholz, David K, Limoli, Dominique H, Rosen, Bradley H, Yan, Ziying, Bartels, Douglas J, Engelhardt, John F

“…Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, with F508del being the most prevalent mutation. The…”
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Patterns of viral load decline with telaprevir-based therapy in patients with genotype 1 chronic HCV infection by Picchio, Gaston, De Meyer, Sandra, Dierynck, Inge, Ghys, Anne, Gritz, Linda, Kieffer, Tara L, Bartels, Douglas J, Witek, Jim, Bengtsson, Leif, Luo, Donghan, Kauffman, Robert S, Adda, Nathalie, Sarrazin, Christoph

“…Abstract Background Telaprevir-based therapy is associated with rapid decline in HCV RNA, enabling the application of early futility rules. Objectives To…”
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