Search Results - "BARRETINA, J"

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling by Shrestha, Y, Schafer, E J, Boehm, J S, Thomas, S R, He, F, Du, J, Wang, S, Barretina, J, Weir, B A, Zhao, J J, Polyak, K, Golub, T R, Beroukhim, R, Hahn, W C

“…Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of…”
Get full text

22 The Cancer Cell Line Encyclopedia - Using Preclinical Models to Predict Anticancer Drug Sensitivity by Barretina, J, Caponigro, G, Stransky, N, Venkatesan, K, Margolin, A.A, Kim, S, Wilson, C.J, Lehar, J, Kryukov, G.V, Murray, L, Morrissey, M.P, Sellers, W.R, Schlegel, R, Garraway, L.A

Get full text

Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation by Castedo, M, Ferri, K F, Blanco, J, Roumier, T, Larochette, N, Barretina, J, Amendola, A, Nardacci, R, Métivier, D, Este, J A, Piacentini, M, Kroemer, G

“…Syncytia arising from the fusion of cells expressing a lymphotropic human immunodeficiency virus (HIV)-1-encoded envelope glycoprotein complex (Env) gene with…”
Get full text

Interleukin-7 in Plasma Correlates with CD4 T-Cell Depletion and May Be Associated with Emergence of Syncytium-Inducing Variants in Human Immunodeficiency Virus Type 1-Positive Individuals by Llano, A, Barretina, J, Gutiérrez, A, Blanco, J, Cabrera, C, Clotet, B, Esté, J A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

251 WNT-PATHWAY ACTIVATION IN TWO MOLECULAR CLASSES OF HEPATOCELLULAR CARCINOMA AND EXPERIMENTAL MODULATION BY SORAFENIB by Lachenmayer, A, Alsinet, C, Savic, R, Cabellos, L, Toffanin, S, Hoshida, Y, Villanueva, A, Minguez, B, Newell, P, Tsai, H.-W, Barretina, J, Thung, S, Ward, S.C, Bruix, J, Mazzaferro, V, Schwartz, M, Friedman, S.L, Llovet, J.M

Get full text

CXCR4 and SDF-1 expression in B-cell chronic lymphocytic leukemia and stage of the disease by BARRETINA, J, JUNCA, J, LLANO, A, GUTIERREZ, A, FLORES, A, BLANCO, J, CLOTET, B, ESTE, J. A

“…The pathogenesis of B-cell chronic lymphocytic leukemia (B-CLL) has been linked to an overexpression of the chemokine receptor CXCR4 and increased in vitro…”
Get full text

Stromal-cell-derived factor 1 prevents the emergence of the syncytium-inducing phenotype of HIV-1 in vivo by LLANO, Anuska, BARRETINA, Jordi, BLANCO, Julia, GUTIERREZ, Arantxa, CLOTET, Bonaventura, ESTE, José A

“…In a correlative study, the mean plasma level of the chemokine stromal-cell-derived factor 1 (SDF-1) was lower in subjects with syncytium-inducing (SI) than in…”
Get full text

Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K Signaling by Gewinner, Christina, Wang, Zhigang C., Richardson, Andrea, Teruya-Feldstein, Julie, Etemadmoghadam, Dariush, Bowtell, David, Barretina, Jordi, Lin, William M., Rameh, Lucia, Salmena, Leonardo, Pandolfi, Pier Paolo, Cantley, Lewis C.

“…We report that knocking down the expression of inositol polyphosphate 4-phosphatase type II (INPP4B) in human epithelial cells, like knockdown of PTEN,…”
Get full text

Evaluation of the putative role of C-C chemokines as protective factors of HIV-1 infection in seronegative hemophiliacs exposed to contaminated hemoderivatives by Barretina, J., Blanco, J., Gutiérrez, A., Puig, L., Altisent, C., Espanol, T., Caragol, I., Clotet, B., Esté, J.A.

“…BACKGROUND: Overproduction of β‐chemokines and genetic variations in chemokine receptors have been correlated with protection against infection by HIV‐1 or…”
Get full text

Abstract PD8-05: Comparative analysis of the genomic landscape of breast cancers from women of African and European ancestry by Olopade, OI, Pitt, JJ, Riester, M, Odetunde, A, Yoshimatsu, T, Labrot, E, Ademola, A, Sanni, A, Okedere, B, Mahan, S, Nwosu, I, Leary, R, Ajani, M, Johnson, RS, Sveen, E, Zheng, Y, Wang, S, Fitzgerald, DJ, Grundstad, J, Tuteja, J, Clayton, W, Khramtsova, G, Oludara, M, Omodele, F, Benson, O, Adeoye, A, Morhason-Bello, O, Ogundiran, T, Babalola, C, Popoola, A, Morrissey, M, Chen, L, Huo, D, Falusi, A, Winckler, W, Obafunwa, J, Papoutsakis, D, Ojengbede, O, White, KP, Ibrahim, N, Oluwasola, O, Barretina, J

“…Abstract Objectives: Paucity of data on populations of African Ancestry in clinical trials continues to limit our ability to design and implement innovative…”
Get full text

Abstract P6-03-17: Genomic landscape of breast cancers from women of African ancestry across the diaspora by Olopade, OI, Odetunde, A, Riester, M, Yoshimatsu, T, Labrot, E, Ademola, A, Sanni, A, Okedere, B, Mahan, S, Nwosu, I, Leary, R, Ajani, M, Johnson, RS, Sveen, E, Zheng, Y, Clayton, W, Khramtsova, G, Oludara, M, Omodele, F, Benson, O, Adeoye, A, Morhason-Bello, O, Ogundiran, T, Babalola, C, Popoola, A, Morrissey, M, Huo, D, Falusi, A, Winckler, W, Obafunwa, J, Papoutsakis, D, Ojengbede, O, Ibrahim, N, Oluwasola, O, Barretina, J

“…Abstract Objectives: Of all ethnic/racial groups, age-standardized mortality rate from breast cancer is highest for African American women in the US for…”
Get full text

High Level of Coreceptor-independent HIV Transfer Induced by Contacts between Primary CD4 T Cells by Blanco, Julià, Bosch, Berta, Fernández-Figueras, María Teresa, Barretina, Jordi, Clotet, Bonaventura, Esté, José A.

“…Cell-to-cell virus transmission is one of the most efficient mechanisms of human immunodeficiency virus (HIV) spread, requires CD4 and coreceptor expression in…”
Get full text

Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope by Castedo, Maria, Roumier, Thomas, Blanco, Julià, Ferri, Karine F., Barretina, Jordi, Tintignac, Lionel A., Andreau, Karine, Perfettini, Jean-Luc, Amendola, Alessandra, Nardacci, Roberta, Leduc, Philip, Ingber, Donald E., Druillennec, Sabine, Roques, Bernard, Leibovitch, Serge A., Vilella-Bach, Montserrat, Chen, Jie, Este, José A., Modjtahedi, Nazanine, Piacentini, Mauro, Kroemer, Guido

“…Syncytia arising from the fusion of cells expressing the HIV‐1‐encoded Env gene with cells expressing the CD4/CXCR4 complex undergo apoptosis following the…”
Get full text

R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism by Blanco, J, Barretina, J, Clotet, B, Este, JA

“…The use of CXC chemokine receptor 4 (CXCR4) and CC chemokine receptor 5 (CCR5) by X4 and R5 human immunodeficiency virus (HIV) envelopes (Env) influences HIV…”
Get full text

Identification of ALK gene alterations in urothelial carcinoma (UC) by Bellmunt, J., Selvarajah, S., Rodig, S., Salido, M., Costa, I., Bellosillo, B., Werner, L., Namgyal, C., Schutz, F. A. B., Pons, F., O'Brien, R., Barretina, J., Signoretti, S., Loda, M., Albanell, J., Choueiri, T. K., Berman, D. M., Kantoff, P. W., Rosenberg, J. E.

“…Abstract only…”
Get full text

Identification of a novel urothelial carcinoma (UC) biomarker of lethality by Rosenberg, J. E., Werner, L., Selvarajah, S., Weir, B., Regan, M. M., Jacobus, S. J., Berman, D. M., Schutz, F. A. B., O'Brien, R., Choueiri, T. K., Barretina, J., Signoretti, S., Loda, M., Guancial, E. A., Gallardo, E., Rojo, F. G., Lloreta, J., Hahn, W. C., Kantoff, P. W., Bellmunt, J.

“…Abstract only…”
Get full text

Cell-Surface-Expressed HIV-1 Envelope Induces the Death of CD4 T Cells during GP41-Mediated Hemifusion-like Events by Blanco, Julià, Barretina, Jordi, Ferri, Karine F., Jacotot, Etienne, Gutiérrez, Arantxa, Armand-Ugón, Mercedes, Cabrera, Cecilia, Kroemer, Guido, Clotet, Bonaventura, Esté, José A.

“…Cells expressing the HIV-1 envelope glycoprotein complex (gp120/gp41, Env) induce the death of target cells either after cell-to-cell fusion or after…”
Get full text

Immunological and virological study of enfuvirtide-treated HIV-positive patients by BARRETINA, Jordi, BLANCO, Julia, BONJOCH, Anna, LLANO, Anuska, CLOTET, Bonaventura, ESTE, José A

“…To evaluate the predictive value and evolution of immunological and virological parameters related to HIV entry and pathogenesis in patients receiving…”
Get full text

The CXCR4 Antagonist AMD3100 Efficiently Inhibits Cell-Surface-Expressed Human Immunodeficiency Virus Type 1 Envelope-Induced Apoptosis by BLANCO, J, BARRETINA, J, HENSON, G, BRIDGER, G, DE CLERCQ, E, CLOTET, B, ESTE, J. A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Anti-HIV activity of a novel aminoglycoside-arginine conjugate by Cabrera, Cecilia, Gutiérrez, Arantxa, Barretina, Jordi, Blanco, Julià, Litovchick, Alexander, Lapidot, Aviva, Clotet, Bonaventura, Esté, José A

“…We have previously described conjugates of L-arginine with aminoglycosides (AAC) that have shown anti-human immunodeficiency virus type 1 (HIV-1) activity in…”
Get full text