Search Results - "BARR, AMY J."

Akt Activity Negatively Regulates Phosphorylation of AMP-activated Protein Kinase in the Heart by Kovacic, Suzanne, Soltys, Carrie-Lynn M., Barr, Amy J., Shiojima, Ichiro, Walsh, Kenneth, Dyck, Jason R.B.

“…In the heart, insulin stimulates a variety of kinase cascades and controls glucose utilization. Because insulin is able to activate Akt and inactivate…”
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Characterization of cardiac malonyl-CoA decarboxylase and its putative role in regulating fatty acid oxidation by Dyck, J R, Barr, A J, Barr, R L, Kolattukudy, P E, Lopaschuk, G D

“…Malonyl-CoA is a potent inhibitor of fatty acid uptake into the mitochondria. Although the synthesis of malonyl-CoA in the heart by acetyl-CoA carboxylase…”
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Novel O-palmitolylated beta-E1 subunit of pyruvate dehydrogenase is phosphorylated during ischemia/reperfusion injury by Folmes, Clifford Dl, Sawicki, Grzegorz, Cadete, Virgilio Jj, Masson, Grant, Barr, Amy J, Lopaschuk, Gary D

“…During and following myocardial ischemia, glucose oxidation rates are low and fatty acids dominate as a source of oxidative metabolism. This metabolic…”
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258-LB: Vitamin D Directly Regulates TRPV1 Channel Activity and May Play an Important Role in the Autoimmune Disease of Type 1 Diabetes by LONG, WENTONG, FATEHI, MOHAMMAD, SONI, SHUBHAM, PANIGRAHI, RASHMI, KELLY, REES G., PHILIPPAERT, KOENRAAD, BARR, AMY J., HELD, MORGANNE, YU, YI, CAMPBELL, SCOTT A., ONDRUSOVA, KATARINA, BALDWIN, TROY, LEMIEUX, JOANNE, LIGHT, PETER E.

“…The autoimmune disease of type 1 diabetes (T1D) results in the immune destruction of β-cells. Recent studies suggest supplementation of vitamin D along can…”
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Activation of Akt protects alveoli from neonatal oxygen-induced lung injury by Alphonse, Rajesh S, Vadivel, Arul, Coltan, Lavinia, Eaton, Farah, Barr, Amy J, Dyck, Jason R B, Thébaud, Bernard

“…Bronchopulmonary dysplasia (BPD) is the main complication of extreme prematurity, resulting in part from mechanical ventilation and oxygen therapy. Currently,…”
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Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy by Noga, Anna A, Soltys, Carrie-Lynn M, Barr, Amy J, Kovacic, Suzanne, Lopaschuk, Gary D, Dyck, Jason R B

“…AMP-activated protein kinase (AMPK) is a major metabolic regulator in the cardiac myocyte. Recently, LKB1 was identified as a kinase that regulates AMPK. Using…”
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Phosphorylation control of cardiac acetyl‐CoA carboxylase by cAMP‐dependent protein kinase and 5′‐AMP activated protein kinase by Dyck, Jason R. B., Kudo, Naomi, Barr, Amy J., Davies, Stephen P., Hardie, D. Grahame, Lopaschuk, Gary D.

“…Acetyl‐CoA carboxylase (ACC) is regarded in liver and adipose tissue to be the rate‐limiting enzyme for fatty acid biosynthesis; however, in heart tissue it…”
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Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism by DYCK, Jason R. B., BERTHIAUME, Luc G., THOMAS, Panakkezhum D., KANTOR, Paul F., BARR, Amy J., BARR, Rick, SINGH, Dyal, HOPKINS, Teresa A., VOILLEY, Nicolas, PRENTKI, Marc, LOPASCHUK, Gary D.

“…In the liver, malonyl-CoA is central to many cellular processes, including both fatty acid biosynthesis and oxidation. Malonyl-CoA decarboxylase (MCD) is…”
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High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5’-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase by Kudo, Naomi, Barr, Amy J., Barr, Rick L., Desai, Snehal, Lopaschuk, Gary D.

“…We determined whether high fatty acid oxidation rates during aerobic reperfusion of ischemic hearts could be explained by a decrease in malonyl-CoA levels,…”
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A22. Ischemia-reperfusion decreases the levels of o-palymitoylated form of PDHβ, and triggers phosphorylation of PDHβ by Folmes, Clifford D.L., Sawicki, Grzegorz, Barr, Amy J., Lopaschuk, Gary D.

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Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. Vol. 278 (2003) 39422-39427 by Kovacic, Suzanne, Soltys, Carrie-Lynn M., Barr, Amy J., Shiojima, Ichiro, Walsh, Kenneth, Dyck, Jason R.B.

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Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism by Dyck, J R, Berthiaume, L G, Thomas, P D, Kantor, P F, Barr, A J, Barr, R, Singh, D, Hopkins, T A, Voilley, N, Prentki, M, Lopaschuk, G D

“…In the liver, malonyl-CoA is central to many cellular processes, including both fatty acid biosynthesis and oxidation. Malonyl-CoA decarboxylase (MCD) is…”
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High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5′-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase by Naomi Kudo, Amy J. Barr, Rick L. Barr, Snehal Desai, Gary D. Lopaschuk

“…We determined whether high fatty acid oxidation rates during aerobic reperfusion of ischemic hearts could be explained by a decrease in malonyl-CoA levels,…”
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