Search Results - "BARONI, M. G"
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Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent
Published in International Journal of Obesity (01-01-2010)“…Context: The PNPLA3 I148M variant (rs738409) is robustly associated with hepatic steatosis. Intriguingly, initial findings in cohorts with a mean body mass…”
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Cardiovascular risk reduction throughout GLP-1 receptor agonist and SGLT2 inhibitor modulation of epicardial fat
Published in Journal of endocrinological investigation (01-03-2022)“…Epicardial adipose tissue is a novel cardiovascular risk factor. It plays a role in the progression of coronary artery disease, heart failure and atrial…”
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High prevalence of diabetes‐specific autoimmunity in first‐degree relatives of Sardinian patients with type 1 diabetes
Published in Diabetes/metabolism research and reviews (01-03-2017)“…Background The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person‐years). Recommendations of…”
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Prevalence of Type 1 diabetes autoantibodies (GAD and IA2) in Sardinian children and adolescents with autoimmune thyroiditis
Published in Diabetic medicine (01-08-2011)“…Diabet. Med. 28, 896–899 (2011) Aims Type 1 diabetes and autoimmune thyroiditis are common autoimmune diseases characterized by the presence of autoantibodies…”
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ANGPTL4 gene E40K variation protects against obesity‐associated dyslipidemia in participants with obesity
Published in Obesity science & practice (01-02-2019)“…Summary Objective ANGPTL4 inhibits lipoprotein lipase in adipose tissue, regulating plasma triglycerides levels. In persons with obesity plasma ANGPTL4 levels…”
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Sick fat: the good and the bad of old and new circulating markers of adipose tissue inflammation
Published in Journal of endocrinological investigation (01-11-2019)“…Adipose tissue (AT) is one of the largest endocrine organs contributing to metabolic homeostasis. The functional pleiotropism of AT depends on its ability to…”
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Semaglutide in routine clinical practice: interesting news from real-world evidence
Published in Journal of endocrinological investigation (01-08-2022)Get full text
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Search for genetic variants of the SYNTAXIN 1A (STX1A) gene: the -352 A>T variant in the STX1A promoter associates with impaired glucose metabolism in an Italian obese population
Published in International Journal of Obesity (01-03-2008)“…Objective: To test if sequence variations of the SYNTAXIN 1A ( STX1A ) gene contribute to the susceptibility to type 2 diabetes in a cohort of overweight/obese…”
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The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance
Published in Diabetologia (01-03-2001)“…Insulin resistance is recognised as the core factor in the pathogenesis of Type II (non-insulin-dependent) diabetes mellitus, hypertension and atherosclerosis…”
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Biochemical liver damage during gender affirming therapy in trans adults assigned female at birth: a meta-analysis
Published in Journal of endocrinological investigation (22-06-2024)“…To assess the effects of testosterone (T)-based gender affirming hormone therapy (GAHT) on liver blood tests (LBTs) in assigned female at birth adults, using a…”
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Clinical application of best practice guidelines for the genetic diagnosis of MODY2 and MODY3
Published in Diabetic medicine (01-11-2010)Get full text
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Independent association of hypovitaminosis d with non-alcoholic fatty liver disease in people with chronic spinal cord injury: a cross-sectional study
Published in Journal of endocrinological investigation (01-01-2024)“…Purpose Non-alcoholic fatty liver disease (NAFLD) and hypovitaminosis D are highly prevalent in people with spinal cord injury (SCI) and could exert an…”
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Analysis of TBC1D4 in patients with severe insulin resistance
Published in Diabetologia (01-06-2010)Get full text
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14
Circulating IL-8 levels are increased in patients with type 2 diabetes and associated with worse inflammatory and cardiometabolic profile
Published in Acta diabetologica (01-10-2017)“…Aims Interleukin-8 (IL-8) is a chemokine involved in systemic immunity, macrophages infiltration and activation in adipose tissue and may play a significant…”
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The single-point insulin sensitivity estimator (SPISE) index is a strong predictor of abnormal glucose metabolism in overweight/obese children: a long-term follow-up study
Published in Journal of endocrinological investigation (01-01-2022)“…Purpose To investigate the relationship between the single-point insulin sensitivity estimator (SPISE) index, an insulin sensitivity indicator validated in…”
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The G972R variant of the insulin receptor substrate-1 gene impairs insulin signaling and cell differentiation in 3T3L1 adipocytes; treatment with a PPARγ agonist restores normal cell signaling and differentiation
Published in Journal of endocrinology (01-02-2006)“…The insulin receptor substrate-1 (IRS-1) plays a central role in insulin sensitivity, and association studies have shown that the IRS-1 G972R variant is a risk…”
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Chronic urticaria and thyroid autoimmunity: a meta-analysis of case–control studies
Published in Journal of endocrinological investigation (01-07-2022)“…Purpose Autoimmunity has been implicated in some patients with idiopathic chronic urticaria (CU). Because of the frequency of autoimmune thyroid diseases,…”
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Subclinical vascular alterations in young adults with type 1 diabetes detected by arterial tonometry
Published in Diabetes/metabolism research and reviews (01-11-2009)“…Background Diabetes mellitus is characterized by a very high prevalence of atherosclerotic disease. Aims of this study were to determine arterial compliance…”
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High uric acid, reduced glomerular filtration rate and non-alcoholic fatty liver in young people with obesity
Published in Journal of endocrinological investigation (01-04-2020)“…Objective To evaluate the association between high uric acid (UA), reduced estimated glomerular filtration rate (eGFR), and non-alcoholic fatty liver disease…”
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Impaired fasting glucose and impaired glucose tolerance in children and adolescents with overweight/obesity
Published in Journal of endocrinological investigation (01-04-2017)“…Objective To investigate in a large sample of overweight/obese (OW/OB) children and adolescents the prevalence of prediabetic phenotypes such as impaired…”
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