Search Results - "BARNICH, Nicolas"

Adherent-Invasive E. coli : Update on the Lifestyle of a Troublemaker in Crohn's Disease by Chervy, Mélissa, Barnich, Nicolas, Denizot, Jérémy

“…Besides genetic polymorphisms and environmental factors, the intestinal microbiota is an important factor in the etiology of Crohn's disease (CD). Among…”
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Microbiota, Inflammation and Colorectal Cancer by Lucas, Cécily, Barnich, Nicolas, Nguyen, Hang Thi Thu

“…Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a multifactorial disease involving genetic, environmental and lifestyle risk…”
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Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli by Desvaux, Mickaël, Dalmasso, Guillaume, Beyrouthy, Racha, Barnich, Nicolas, Delmas, Julien, Bonnet, Richard

“…is a versatile bacterial species that includes both harmless commensal strains and pathogenic strains found in the gastrointestinal tract in humans and…”
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Colibactin: More Than a New Bacterial Toxin by Faïs, Tiphanie, Delmas, Julien, Barnich, Nicolas, Bonnet, Richard, Dalmasso, Guillaume

“…Cyclomodulins are bacterial toxins that interfere with the eukaryotic cell cycle. A new cyclomodulin called colibactin, which is synthetized by the genomic…”
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Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation by Agus, Allison, Denizot, Jérémy, Thévenot, Jonathan, Martinez-Medina, Margarita, Massier, Sébastien, Sauvanet, Pierre, Bernalier-Donadille, Annick, Denis, Sylvain, Hofman, Paul, Bonnet, Richard, Billard, Elisabeth, Barnich, Nicolas

“…Recent advances have shown that the abnormal inflammatory response observed in CD involves an interplay among intestinal microbiota, host genetics and…”
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The Nutrition-Microbiota-Physical Activity Triad: An Inspiring New Concept for Health and Sports Performance by Boisseau, Nathalie, Barnich, Nicolas, Koechlin-Ramonatxo, Christelle

“…The human gut microbiota is currently the focus of converging interest in many diseases and sports performance. This review presents gut microbiota as a real…”
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Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis by Imai, Jin, Kitamoto, Sho, Sugihara, Kohei, Nagao-Kitamoto, Hiroko, Hayashi, Atsushi, Morhardt, Tina L., Kuffa, Peter, Higgins, Peter D. R., Barnich, Nicolas, Kamada, Nobuhiko

“…Intestinal fibrosis is a severe complication in patients with Crohn's disease (CD). Unfortunately, the trigger leading to the development of intestinal…”
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Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation by Viennois, Emilie, Bretin, Alexis, Dubé, Philip E., Maue, Alexander C., Dauriat, Charlène J.G., Barnich, Nicolas, Gewirtz, Andrew T., Chassaing, Benoit

“…Dietary emulsifiers carboxymethylcellulose (CMC) and polysorbate-80 (P80) disturb gut microbiota, promoting chronic inflammation. Mice with minimal microbiota…”
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Colibactin‐positive Escherichia coli induce a procarcinogenic immune environment leading to immunotherapy resistance in colorectal cancer by Lopès, Amélie, Billard, Elisabeth, Casse, Al Hassan, Villéger, Romain, Veziant, Julie, Roche, Gwenaëlle, Carrier, Guillaume, Sauvanet, Pierre, Briat, Arnaud, Pagès, Franck, Naimi, Souad, Pezet, Denis, Barnich, Nicolas, Dumas, Bruno, Bonnet, Mathilde

“…Colibactin‐producing E. coli (CoPEC) are frequently detected in colorectal cancer (CRC) and exhibit procarcinogenic properties. Because increasing evidence…”
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Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment? by Villéger, Romain, Lopès, Amélie, Carrier, Guillaume, Veziant, Julie, Billard, Elisabeth, Barnich, Nicolas, Gagnière, Johan, Vazeille, Emilie, Bonnet, Mathilde

“…Recently, preclinical and clinical studies targeting several types of cancer strongly supported the key role of the gut microbiota in the modulation of host…”
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Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model by Ribière, Céline, Peyret, Pierre, Parisot, Nicolas, Darcha, Claude, Déchelotte, Pierre J., Barnich, Nicolas, Peyretaillade, Eric, Boucher, Delphine

“…Gut microbiota dysbiosis are associated with a wide range of human diseases, including inflammatory bowel diseases. The physiopathology of these diseases has…”
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Adaptation of adherent-invasive E. coli to gut environment: Impact on flagellum expression and bacterial colonization ability by Sevrin, Gwladys, Massier, Sébastien, Chassaing, Benoit, Agus, Allison, Delmas, Julien, Denizot, Jérémy, Billard, Elisabeth, Barnich, Nicolas

“…The pathogenesis of Crohn's disease (CD) is multifactorial and involves genetic susceptibility, environmental triggers and intestinal microbiota…”
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Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM by Carvalho, Frédéric A, Barnich, Nicolas, Sivignon, Adeline, Darcha, Claude, Chan, Carlos H F, Stanners, Clifford P, Darfeuille-Michaud, Arlette

“…Abnormal expression of CEACAM6 is observed at the apical surface of the ileal epithelium in Crohn's disease (CD) patients, and CD ileal lesions are colonized…”
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Emerging Role of Exosomes in Diagnosis and Treatment of Infectious and Inflammatory Bowel Diseases by Larabi, Anaïs, Barnich, Nicolas, Nguyen, Hang Thi Thu

“…To communicate with each other, cells release exosomes that transfer their composition, including lipids, proteins and nucleic acids, to neighboring cells,…”
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Exosomes transfer miRNAs from cell-to-cell to inhibit autophagy during infection with Crohn's disease-associated adherent-invasive E. coli by Larabi, Anaïs, Dalmasso, Guillaume, Delmas, Julien, Barnich, Nicolas, Nguyen, Hang Thi Thu

“…Adherent-invasive E. coli (AIEC), which abnormally colonize the intestinal mucosa of Crohn's disease (CD) patients, are able to adhere to and invade intestinal…”
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Metabolic adaptation of adherent-invasive Escherichia coli to exposure to bile salts by Delmas, Julien, Gibold, Lucie, Faïs, Tiphanie, Batista, Sylvine, Leremboure, Martin, Sinel, Clara, Vazeille, Emilie, Cattoir, Vincent, Buisson, Anthony, Barnich, Nicolas, Dalmasso, Guillaume, Bonnet, Richard

“…The adherent-invasive Escherichia coli (AIEC), which colonize the ileal mucosa of Crohn’s disease patients, adhere to intestinal epithelial cells, invade them…”
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Genes mcr improve the intestinal fitness of pathogenic E. coli and balance their lifestyle to commensalism by Dalmasso, Guillaume, Beyrouthy, Racha, Brugiroux, Sandrine, Ruppé, Etienne, Guillouard, Laurent, Bonnin, Virginie, Saint-Sardos, Pierre, Ghozlane, Amine, Gaumet, Vincent, Barnich, Nicolas, Delmas, Julien, Bonnet, Richard

“…The plasmid-mediated resistance gene mcr-1 confers colistin resistance in Escherichia coli and paves the way for the evolution to pan-drug resistance. We…”
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Fecal dysbiosis associated with colonic hypersensitivity and behavioral alterations in chronically Blastocystis-infected rats by Defaye, Manon, Nourrisson, Céline, Baudu, Elodie, Lashermes, Amandine, Meynier, Maëva, Meleine, Mathieu, Wawrzyniak, Ivan, Bonnin, Virginie, Barbier, Julie, Chassaing, Benoit, Godfraind, Catherine, Gelot, Agathe, Barnich, Nicolas, Ardid, Denis, Bonnet, Mathilde, Delbac, Frédéric, Carvalho, Frédéric Antonio, Poirier, Philippe

“…Background: Infectious gastroenteritis is a risk factor for the development of post-infectious Irritable Bowel Syndrome (PI-IBS). Recent clinical studies…”
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When Pathobiont-Carbohydrate Interaction Turns Bittersweet by Barnich, Nicolas, Chassaing, Benoit

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High intensity interval training promotes total and visceral fat mass loss in obese Zucker rats without modulating gut microbiota by Maillard, Florie, Vazeille, Emilie, Sauvanet, Pierre, Sirvent, Pascal, Combaret, Lydie, Sourdrille, Antoine, Chavanelle, Vivien, Bonnet, Richard, Otero, Yolanda Fernandez, Delcros, Geoffrey, Barnich, Nicolas, Boisseau, Nathalie

“…Increased visceral adipose tissue and dysbiosis in the overweight and obese promote chronic inflammation. The aim of this study was to compare the effects of…”
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