Search Results - "BARNATHAN, Elliot S"
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CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab
Published in The European respiratory journal (01-12-2015)“…The objective of this study was to determine the safety and efficacy of carlumab in the treatment of idiopathic pulmonary fibrosis (IPF).A phase 2, randomised,…”
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Improved Benefit Risk Profile of Rivaroxaban in a Subpopulation of the MAGELLAN Study
Published in Clinical and applied thrombosis/hemostasis (2019)“…Acutely ill medical patients are at risk of venous thromboembolism (VTE) and VTE-related mortality during hospitalization and posthospital discharge, but…”
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Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma
Published in Chest (01-06-2014)“…Background The nature of bronchial mucosal inflammation and its physiologic and clinical significance in rhinovirus-induced asthma exacerbations is unclear. We…”
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Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients
Published in Journal of allergy and clinical immunology (01-09-2017)“…Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic…”
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The Safety and Efficacy of Infliximab in Moderate to Severe Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-05-2007)“…Chronic obstructive pulmonary disease (COPD) is a progressive, smoking-related, inflammatory lung disease in which tumor necrosis factor-alpha is overexpressed…”
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Quantitative Benefit-Risk Evaluation of Rivaroxaban in Patients After Peripheral Arterial Revascularization: The VOYAGER PAD Trial
Published in Journal of the American Heart Association (16-04-2024)“…The VOYAGER PAD (Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery…”
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Association Between Asymptomatic Proximal Deep Vein Thrombosis and Mortality in Acutely Ill Medical Patients
Published in Journal of the American Heart Association (02-03-2021)“…Background Asymptomatic proximal deep vein thrombosis (DVT) is an end point frequently used to evaluate the efficacy of anticoagulant thromboprophylaxis in…”
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Validation and important differences for the Sarcoidosis Assessment Tool. A new patient-reported outcome measure
Published in American journal of respiratory and critical care medicine (01-04-2015)“…Patient-reported outcome (PRO) measures have been developed to measure symptoms and other aspects of health-related quality of life. The Sarcoidosis Assessment…”
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Benefit-Risk of Rivaroxaban for Extended Thromboprophylaxis After Hospitalization for Medical Illness: Pooled Analysis From MAGELLAN and MARINER
Published in Journal of the American Heart Association (16-11-2021)“…Background Thromboprophylaxis extended after hospital discharge in medically ill patients currently is not recommended by practice guidelines because of…”
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A phase 2a study of toreforant, a histamine H4 receptor antagonist, in eosinophilic asthma
Published in Annals of allergy, asthma, & immunology (01-11-2018)“…Data from preclinical and clinical studies support the evaluation of histamine 4 receptor antagonists in the treatment of asthma. Toreforant is a selective…”
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Inference from longitudinal laboratory tests characterizes temporal evolution of COVID-19-associated coagulopathy (CAC)
Published in eLife (17-08-2020)“…Temporal inference from laboratory testing results and triangulation with clinical outcomes extracted from unstructured electronic health record (EHR) provider…”
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Benefit–Risk Assessment of Rivaroxaban for Extended Thromboprophylaxis After Hospitalization for Medical Illness
Published in Journal of the American Heart Association (18-10-2022)“…Background Venous thromboembolism (VTE) often occurs after hospitalization in medically ill patients, but the population benefit–risk of extended…”
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Molecular profiling and gene expression analysis in cutaneous sarcoidosis: The role of interleukin-12, interleukin-23, and the T-helper 17 pathway
Published in Journal of the American Academy of Dermatology (01-06-2012)“…Background Cutaneous sarcoidosis (CS) skin provides relatively noninvasive access to granulomatous sarcoidosis tissue. Objective We sought to explore the role…”
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Benefit of Facilitated Percutaneous Coronary Intervention in High-Risk ST-Segment Elevation Myocardial Infarction Patients Presenting to Nonpercutaneous Coronary Intervention Hospitals
Published in JACC. Cardiovascular interventions (01-10-2009)“…Objectives We hypothesized that patients most likely to benefit would be those at high risk with a shorter duration of acute ischemia and who required transfer…”
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Risk of Severe Bleeding With Extended Rivaroxaban to Prevent Venous Thromboembolism in Acute Medically Ill Patients With Bronchiectasis
Published in Clinical and applied thrombosis/hemostasis (2021)“…Background: Bronchiectasis is a chronic inflammation of the bronchi with recurrent infections and hemoptysis. The MAGELLAN study compared oral rivaroxaban, 10…”
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Extended Thromboprophylaxis in Hospitalized Patients with Heart Failure: A Post Hoc Analysis of the MAGELLAN Study
Published in TH open : companion journal to thrombosis and haemostasis (01-10-2022)“…Abstract This post hoc subgroup analysis examined efficacy and safety outcomes with extended thromboprophylaxis rivaroxaban compared with in-hospital…”
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Hospital-based use of thromboprophylaxis in patients with COVID-19
Published in The Lancet (British edition) (02-05-2020)“…In a case series from China,2 increased D-dimer concentration at time of admission to hospital (>1 μg/mL) was associated with a risk of in-hospital mortality…”
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Inflammatory Profile and Response to Anti-Tumor Necrosis Factor Therapy in Patients with Chronic Pulmonary Sarcoidosis
Published in Clinical and Vaccine Immunology (01-06-2011)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Rivaroxaban Plus Aspirin for Extended Thromboprophylaxis in Acutely Ill Medical Patients: Insights from the MARINER Trial
Published in TH open : companion journal to thrombosis and haemostasis (01-07-2022)“…Abstract Background The MARINER trial evaluated whether postdischarge thromboprophylaxis with rivaroxaban could reduce the primary outcome of symptomatic…”
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Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease
Published in Respiratory research (02-02-2012)“…Chronic obstructive pulmonary disease (COPD) is characterized by progressive worsening of airflow limitation associated with abnormally inflamed airways in…”
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