Search Results - "BARITAKI, Stavroula"

Current Perspectives in Cancer Immunotherapy by Christofi, Theodoulakis, Baritaki, Stavroula, Falzone, Luca, Libra, Massimo, Zaravinos, Apostolos

“…Different immunotherapeutic approaches have proved to be of significant clinical value to many patients with different types of advanced cancer. However, we…”
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RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact by Zaravinos, Apostolos, Bonavida, Benjamin, Chatzaki, Ekaterini, Baritaki, Stavroula

“…RAF-kinase inhibitor protein (RKIP) is a well-established tumor suppressor that is frequently downregulated in a plethora of solid and hematological…”
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Inverse Correlation Between the Metastasis Suppressor RKIP and the Metastasis Inducer YY1: Contrasting Roles in the Regulation of Chemo/Immuno-Resistance in Cancer by Wottrich, Stephanie, Kaufhold, Samantha, Chrysos, Emmanuel, Zoras, Odysseas, Baritaki, Stavroula, Bonavida, Benjamin

“…Abstract Several gene products have been postulated to mediate inherent and/or acquired anticancer drug resistance and tumor metastasis. Among these, the…”
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Dual Effects of Non-Coding RNAs (ncRNAs) in Cancer Stem Cell Biology by Kyriazi, Athina A, Papiris, Efstathios, Kitsos Kalyvianakis, Konstantinos, Sakellaris, George, Baritaki, Stavroula

“…The identification of cancer stem cells (CSCs) as initiators of carcinogenesis has revolutionized the era of cancer research and our perception for the disease…”
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Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer by GANG REN, BARITAKI, Stavroula, DAIGNAULT, Stephanie, AL-MULLA, Fahd, KELLER, Evan, BONAVIDA, Ben, DE LA SERNA, Ivana, YEUNG, Kam C, MARATHE, Himangi, JINGWEI FENG, PARK, Sungdae, BEACH, Sandy, BAZELEY, Peter S, BESHIR, Anwar B, FENTEANY, Gabriel, MEHRA, Rohit

“…Epigenetic modifications such as histone methylation play an important role in human cancer metastasis. Enhancer of zeste homolog 2 (EZH2), which encodes the…”
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Long Non-Coding RNAs (lncRNAs) in Response and Resistance to Cancer Immunosurveillance and Immunotherapy by Eptaminitaki, Giasemi C, Wolff, Nora, Stellas, Dimitris, Sifakis, Konstantinos, Baritaki, Stavroula

“…Long non-coding RNAs (lncRNAs) are critical regulatory elements in cellular functions in states of both normalcy and disease, including cancer. LncRNAs can…”
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Chronic Stress, Inflammation, and Colon Cancer: A CRH System-Driven Molecular Crosstalk by Baritaki, Stavroula, de Bree, Eelco, Chatzaki, Ekaterini, Pothoulakis, Charalabos

“…Chronic stress is thought to be involved in the occurrence and progression of multiple diseases, via mechanisms that still remain largely unknown…”
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Mitochondrial Fraction of Circulating Cell-Free DNA as an Indicator of Human Pathology by Panagopoulou, Maria, Karaglani, Makrina, Tzitzikou, Konstantina, Kessari, Nikoleta, Arvanitidis, Konstantinos, Amarantidis, Kyriakos, Drosos, George I, Gerou, Spyros, Papanas, Nikolaos, Papazoglou, Dimitrios, Baritaki, Stavroula, Constantinidis, Theodoros C, Chatzaki, Ekaterini

“…Circulating cell-free DNA (ccfDNA) of mitochondrial origin (ccf-mtDNA) consists of a minor fraction of total ccfDNA in blood or in other biological fluids…”
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Intratumoral Microbiome: Foe or Friend in Reshaping the Tumor Microenvironment Landscape? by Kyriazi, Athina A, Karaglani, Makrina, Agelaki, Sofia, Baritaki, Stavroula

“…The role of the microbiome in cancer and its crosstalk with the tumor microenvironment (TME) has been extensively studied and characterized. An emerging field…”
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The Breast Cancer Protooncogenes HER2, BRCA1 and BRCA2 and Their Regulation by the iNOS/NOS2 Axis by Lin, Katie, Baritaki, Stavroula, Vivarelli, Silvia, Falzone, Luca, Scalisi, Aurora, Libra, Massimo, Bonavida, Benjamin

“…The expression of inducible nitric oxide synthase (iNOS; NOS2) and derived NO in various cancers was reported to exert pro- and anti-tumorigenic effects…”
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Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1 by Baritaki, Stavroula, Huerta-Yepez, Sara, Sakai, Toshiyuki, Spandidos, Demetrios A, Bonavida, Benjamin

“…Several chemotherapeutic drugs in combination with tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) result in reversal of resistance to…”
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Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: Inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP by Baritaki, Stavroula, Huerta-Yepez, Sara, Sahakyan, Anna, Karagiannides, Iordanis, Bakirtzi, Kyriaki, Jazirehi, Ali, Bonavida, Benjamin

“…The role of nitric oxide (NO) in cancer has been controversial and is based on the levels of NO and the responsiveness of the tumor type. It remains unclear…”
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Novel therapeutic applications of nitric oxide donors in cancer: Roles in chemo- and immunosensitization to apoptosis and inhibition of metastases by Bonavida, Benjamin, Baritaki, Stavroula, Huerta-Yepez, Sara, Vega, Mario I., Chatterjee, Devasis, Yeung, Kam

“…The treatment of primary tumors results in an initial response to approved conventional therapeutics. However, recurrences and malignancies develop as a result…”
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Regulation of Tumor Cell Sensitivity to TRAIL-Induced Apoptosis by the Metastatic Suppressor Raf Kinase Inhibitor Protein via Yin Yang 1 Inhibition and Death Receptor 5 Up-Regulation by Baritaki, Stavroula, Katsman, Alina, Chatterjee, Devasis, Yeung, Kam C, Spandidos, Demetrios A, Bonavida, Benjamin

“…Raf-1 kinase inhibitor protein (RKIP) has been implicated in the regulation of cell survival pathways and metastases, and is poorly expressed in tumors. We…”
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Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer by Georgiou, Maria, Lougiakis, Nikolaos, Tenta, Roxane, Gioti, Katerina, Baritaki, Stavroula, Gkaralea, Lydia-Evangelia, Deligianni, Elisavet, Marakos, Panagiotis, Pouli, Nicole, Stellas, Dimitris

“…Purine analogues are important therapeutic tools due to their affinity to enzymes or receptors that are involved in critical biological processes. In this…”
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TRAF6 Activation in Multiple Myeloma: A Potential Therapeutic Target by Liu, Hong, Tamashiro, Samantha, Baritaki, Stavroula, Penichet, Manuel, Yu, Youhua, Chen, Haiming, Berenson, James, Bonavida, Benjamin

“…Abstract Multiple myeloma (MM) is an incurable B-lymphocyte malignancy. New therapeutic options have become available during the past several years; however…”
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Mcl-1 and YY1 inhibition and induction of DR5 by the BH3-mimetic Obatoclax (GX15-070) contribute in the sensitization of B-NHL cells to TRAIL apoptosis by Martínez-Paniagua, Melisa A., Baritaki, Stavroula, Huerta-Yepez, Sara, Ortiz-Navarrete, Vianney F., González-Bonilla, Cesar, Bonavida, Benjamin, Vega, Mario I.

“…The pan Bcl-2 family antagonist Obatoclax (GX15-070), currently in clinical trials, was shown to sensitize TRAIL-resistant tumors to TRAIL-mediated apoptosis…”
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BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma by Zaravinos, Apostolos, Kanellou, Peggy, Baritaki, Stavroula, Bonavida, Benjamin, Spandidos, Demetrios A.

“…Background. Actinic keratosis (AK) is a well-established pre-cancerous skin lesion that has the potential to progress to squamous cell carcinoma (SCC)…”
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Evaluation of GenoType Mycobacteria Direct Assay in Comparison with Gen-Probe Mycobacterium tuberculosis Amplified Direct Test and GenoType MTBDRplus for Direct Detection of Mycobacterium tuberculosis Complex in Clinical Samples by Neonakis, Ioannis K, Gitti, Zoe, Baritaki, Stavroula, Petinaki, Efi, Baritaki, Maria, Spandidos, Demetrios A

“…Three molecular assays were evaluated for the direct detection of Mycobacterium tuberculosis complex bacteria in 125 respiratory and 22 nonrespiratory samples…”
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Reversal of Tumor Resistance to Apoptotic Stimuli by Alteration of Membrane Fluidity: Therapeutic Implications by Baritaki, Stavroula, Apostolakis, Stavros, Kanellou, Peggy, Dimanche‐Boitrel, Marie‐Therese, Spandidos, Demetrios A., Bonavida, Benjamin

“…In recent years, significant development and improvement have been observed in the treatment of cancer; however, relapses and recurrences occur frequently and…”
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