Search Results - "BARBIERI, Ottavia"

Curcumin inhibits prostate cancer metastasis in vivo by targeting the inflammatory cytokines CXCL1 and -2 by KILLIAN, Peter H, KRONSKI, Emanuel, MICHALIK, Katharina M, BARBIERI, Ottavia, ASTIGIANO, Simonetta, SOMMERHOFF, Christian P, PFEFFER, Ulrich, NERLICH, Andreas G, BACHMEIER, Beatrice E

“…In America and Western Europe, prostate cancer is the second leading cause of death in men. Emerging evidence suggests that chronic inflammation is a major…”
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Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation by Rotondo, Rita, Bertolotto, Maria, Barisione, Gaia, Astigiano, Simonetta, Mandruzzato, Susanna, Ottonello, Luciano, Dallegri, Franco, Bronte, Vincenzo, Ferrini, Silvano, Barbieri, Ottavia

“…Arginase‐dependent inhibition of T cell proliferation results from regulated exocytosis of gelatinase and azurophil granules released by activated…”
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Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation by Magnone, Mirko, Emionite, Laura, Guida, Lucrezia, Vigliarolo, Tiziana, Sturla, Laura, Spinelli, Sonia, Buschiazzo, Ambra, Marini, Cecilia, Sambuceti, Gianmario, De Flora, Antonio, Orengo, Anna Maria, Cossu, Vanessa, Ferrando, Sara, Barbieri, Ottavia, Zocchi, Elena

“…Abscisic acid (ABA) is a plant hormone active also in mammals where it regulates, at nanomolar concentrations, blood glucose homeostasis. Here we investigated…”
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miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2 by Kronski, Emanuel, Fiori, Micol E., Barbieri, Ottavia, Astigiano, Simonetta, Mirisola, Valentina, Killian, Peter H., Bruno, Antonino, Pagani, Arianna, Rovera, Francesca, Pfeffer, Ulrich, Sommerhoff, Christian P., Noonan, Douglas M., Nerlich, Andreas G., Fontana, Laura, Bachmeier, Beatrice E.

“…Chronic inflammation is a major risk factor for the development and metastatic progression of cancer. We have previously reported that the chemopreventive…”
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Multifocal Signal Modulation Therapy by Celecoxib: A Strategy for Managing Castration-Resistant Prostate Cancer by Benelli, Roberto, Barboro, Paola, Costa, Delfina, Astigiano, Simonetta, Barbieri, Ottavia, Capaia, Matteo, Poggi, Alessandro, Ferrari, Nicoletta

“…Prostate cancer (PCa) is a significant health concern throughout the world. Standard therapy for advanced disease consists of anti-androgens, however, almost…”
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IL‐8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer by Rotondo, Rita, Barisione, Gaia, Mastracci, Luca, Grossi, Francesco, Orengo, Anna Maria, Costa, Roberta, Truini, Mauro, Fabbi, Marina, Ferrini, Silvano, Barbieri, Ottavia

“…Arginase 1 (ARG1) inhibits T‐cell proliferation by degrading extracellular arginine, which results in decreased responsiveness of T cells to CD3/TCR…”
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Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development by Sarogni, Patrizia, Palumbo, Orazio, Servadio, Adele, Astigiano, Simonetta, D'Alessio, Barbara, Gatti, Veronica, Cukrov, Dubravka, Baldari, Silvia, Pallotta, Maria Michela, Aretini, Paolo, Dell'Orletta, Felice, Soddu, Silvia, Carella, Massimo, Toietta, Gabriele, Barbieri, Ottavia, Fontanini, Gabriella, Musio, Antonio

“…Cancer cells are characterized by chromosomal instability (CIN) and it is thought that errors in pathways involved in faithful chromosome segregation play a…”
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Systemic alkalinisation delays prostate cancer cell progression in TRAMP mice by Astigiano, Simonetta, Puglisi, Andrea, Mastracci, Luca, Fais, Stefano, Barbieri, Ottavia

“…The microenvironment of solid tumours is extremely acidic and this condition arises since the precancerous stage. This acidic milieu could therefore provide a…”
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In vivo generation of decidual natural killer cells from resident hematopoietic progenitors by Chiossone, Laura, Vacca, Paola, Orecchia, Paola, Croxatto, Daniele, Damonte, Patrizia, Astigiano, Simonetta, Barbieri, Ottavia, Bottino, Cristina, Moretta, Lorenzo, Mingari, Maria Cristina

“…Decidual natural killer cells accumulate at the fetal-maternal interface and play a key role in a successful pregnancy. However, their origin is still unknown…”
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Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231 by Morini, Monica, Astigiano, Simonetta, Gitton, Yorick, Emionite, Laura, Mirisola, Valentina, Levi, Giovanni, Barbieri, Ottavia

“…The DLX gene family encodes for homeobox transcription factors involved in the control of morphogenesis and tissue homeostasis. Their expression can be…”
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BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development by Vieux-Rochas, Maxence, Bouhali, Kamal, Mantero, Stefano, Garaffo, Giulia, Provero, Paolo, Astigiano, Simonetta, Barbieri, Ottavia, Caratozzolo, Mariano F, Tullo, Apollonia, Guerrini, Luisa, Lallemand, Yvan, Robert, Benoît, Levi, Giovanni, Merlo, Giorgio R

“…The Dlx and Msx homeodomain transcription factors play important roles in the control of limb development. The combined disruption of Msx1 and Msx2, as well as…”
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TAp73 is downregulated in oocytes from women of advanced reproductive age by Guglielmino, Maria Rosa, Santonocito, Manuela, Vento, Marilena, Ragusa, Marco, Barbagallo, Davide, Borzì, Placido, Casciano, Ida, Banelli, Barbara, Barbieri, Ottavia, Astigiano, Simonetta, Scollo, Paolo, Romani, Massimo, Purrello, Michele, Di Pietro, Cinzia

“…Studies on oocyte transcriptome are important to understand the biological pathways involved in oogenesis, totipotence and early embryonic development…”
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Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-α deficiency by Resaz, Roberta, Vanni, Cristina, Segalerba, Daniela, Sementa, Angela R, Mastracci, Luca, Grillo, Federica, Murgia, Daniele, Bosco, Maria Carla, Chou, Janice Y, Barbieri, Ottavia, Varesio, Luigi, Eva, Alessandra

“…Glycogen storage disease type 1a (GSD-1a) is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α), and is characterized by impaired glucose homeostasis…”
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Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5 by Acampora, D, Merlo, G R, Paleari, L, Zerega, B, Postiglione, M P, Mantero, S, Bober, E, Barbieri, O, Simeone, A, Levi, G

“…The Dlx5 gene encodes a Distal-less-related DNA-binding homeobox protein first expressed during early embryonic development in anterior regions of the mouse…”
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Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw by Vieux-Rochas, Maxence, Mantero, Stefano, Heude, Eglantine, Barbieri, Ottavia, Astigiano, Simonetta, Couly, Gérard, Kurihara, Hiroki, Levi, Giovanni, Merlo, Giorgio R.

“…The morphogenesis of the vertebrate skull results from highly dynamic integrated processes involving the exchange of signals between the ectoderm, the…”
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Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws by Vieux-Rochas, Maxence, Coen, Laurent, Sato, Takahiro, Kurihara, Yukiko, Gitton, Yorick, Barbieri, Ottavia, Le Blay, Karine, Merlo, Giorgio, Ekker, Marc, Kurihara, Hiroki, Janvier, Philippe, Levi, Giovanni

“…Intake of retinoic acid (RA) or of its precursor, vitamin A, during early pregnancy is associated with increased incidence of craniofacial lesions. The origin…”
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Abnormal urethra formation in mouse models of Split-hand split-foot malformation type 1 and type 4 by SUZUKI, Kentaro, HARAGUCHI, Ryuma, LEVI, Giovanni, YAMADA, Gen, OGATA, Tsutomu, BARBIERI, Ottavia, ALEGRIA, Olinda, VIEUX-ROCHAS, Maxence, NAKAGATA, Naomi, ITO, Masataka, MILLS, Alea A, KURITA, Takeshi

“…Urogenital birth defects are one of the common phenotypes observed in hereditary human disorders. In particular, limb malformations are often associated with…”
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High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice by Ognibene, Marzia, Barbieri, Ottavia, Vanni, Cristina, Mastracci, Luca, Astigiano, Simonetta, Emionite, Laura, Salani, Barbara, Fedele, Manuela, Resaz, Roberta, Tenca, Claudya, Fais, Franco, Sabatini, Federica, De Santanna, Amleto, Altruda, Fiorella, Varesio, Luigi, Hirsch, Emilio, Eva, Alessandra

“…Dbl is the prototype of a large family of GDP–GTP exchange factors for small GTPases of the Rho family. In vitro, Dbl is known to activate Rho, Rac, and Cdc42…”
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The carboxyl terminal trimer of procollagen I induces pro-metastatic changes and vascularization in breast cancer cells xenografts by Visigalli, Davide, Palmieri, Daniela, Strangio, Antonella, Astigiano, Simonetta, Barbieri, Ottavia, Casartelli, Gianluigi, Zicca, Antonio, Manduca, Paola

“…The COOH terminal peptide of Pro-collagen type I (PICP, also called C3) is chemotactic for endothelial melanoma and breast cancer cells. PICP induces the…”
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Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation by Barbieri, Ottavia, Astigiano, Simonetta, Morini, Monica, Tavella, Sara, Schito, Anna, Corsi, Alessandro, Di Martino, Davide, Bianco, Paolo, Cancedda, Ranieri, Garofalo, Silvio

“…We have generated transgenic mice harboring the deletion of exon 48 in the mouse alpha1(II) procollagen gene (Col2a1). This was the first dominant negative…”
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