Search Results - "BARBACCIA, M. L"

Role of Brain Allopregnanolone in the Plasticity of γ -aminobutyric Acid Type A Receptor in Rat Brain during Pregnancy and after Delivery by Concas, A., Mostallino, M. C., Porcu, P., Follesa, P., Barbaccia, M. L., Trabucchi, M., Purdy, R. H., Grisenti, P., Biggio, G.

“…The relation between changes in brain and plasma concentrations of neurosteroids and the function and structure of γ -aminobutyric acid type A (GABAA)…”
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The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations by Barbaccia, M. L., Roscetti, G., Trabucchi, M., Purdy, R. H., Mostallino, M. C., Concas, A., Biggio, G.

“…This study was undertaken to investigate the relationship between a reduction in brain GABAA receptor function and the cerebro‐cortical content of…”
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Ethanol markedly increases “GABAergic” neurosteroids in alcohol-preferring rats by Barbaccia, Maria Luisa, Affricano, Daniela, Trabucchi, Marco, Purdy, Robert H, Colombo, Giancarlo, Agabio, Roberta, Gessa, Gian Luigi

“…Alcohol administration (1 g/kg, i.p.) increased the levels of the neurosteroids 3α-hydroxy-5α-pregnan-20-one (allopregnanolone) and…”
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2‐Phenyl‐imidazo[1,2‐a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats by Serra, Mariangela, Madau, Paola, Chessa, Maria Francesca, Caddeo, Monica, Sanna, Enrico, Trapani, Giuseppe, Franco, Massimo, Liso, Gaetano, Purdy, Robert H, Barbaccia, Maria Luisa, Biggio, Giovanni

“…Selective activation of peripheral benzodiazepine receptors (PBRs) in adrenal cells and brain oligodendrocytes promotes steroidogenesis. Three…”
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In primary cultures of cerebellar granule cells the activation of N-methyl-D-aspartate-sensitive glutamate receptors induces c-fos mRNA expression by Szekely, A M, Barbaccia, M L, Alho, H, Costa, E

“…L-Glutamate, the natural agonist of quisqualate- and N-methyl-D-aspartate (NMDA)-sensitive excitatory amino acid receptors, elicits a rapid, transient,…”
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Stress and neurosteroids in adult and aged rats by Barbaccia, M.L, Concas, A, Serra, M, Biggio, G

“…—The progesterone derivative 3α-hydroxy-5α-pregnan-20 one (allopregnanolone/AP) and the deoxycorticosterone derivative 3α-21-dihydroxy-5α-pregnan-20 one…”
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Functional correlation between allopregnanolone and [35S]‐TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress by Concas, Alessandra, Mostallino, Maria Cristina, Perra, Chiara, Lener, Raffaela, Roscetti, Gianna, Barbaccia, Maria Luisa, Purdy, Robert H., Biggio, Giovanni

“…1 The relation between changes in the cerebral cortical concentration of allopregnanolone and γ‐aminobutyric acid (GABA) type A receptor function after…”
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Stress-induced increase in brain neuroactive steroids: Antagonism by abecarnil by Barbaccia, Maria L., Roscetti, Gianna, Bolacchi, Francesca, Concas, Alessandra, Mostallino, Maria C., Purdy, Robert H., Biggio, Giovanni

“…Acute foot shock stress elicits a selective and time-dependent increase of neuroactive steroid (pregnenolone, progesterone, allotetrahydrodeoxycorticosterone)…”
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Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation by Barbaccia, M L, Roscetti, G, Trabucchi, M, Cuccheddu, T, Concas, A, Biggio, G

“…In rats habituated to the manipulation that precedes killing (handling-habituated) the cerebral cortical concentrations of pregnenolone and progesterone were…”
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Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production by Ghezzi, P, Santo, E D, Sacco, S, Foddi, C, Barbaccia, M L, Mennini, T

“…Neuroactive steroids such as dehydroepiandrosterone sulfate and pregnenolone inhibit lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF) production…”
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Activation of specific glutamate receptor subtypes increases C-fos proto-oncogene expression in primary cultures of neonatal rat cerebellar granule cells by Szekely, A M, Barbaccia, M L, Costa, E

“…In primary cultures of rat cerebellar granule cells the activation of excitatory amino acid receptors by 1-glutamate enhances the steady state level of c-fos…”
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Dehydroepiandrosterone metabolism in human plasma by Albo, F, Barbaccia, M L, Cavazza, A, Marini, M, Roda, L G

“…The possibility that dehydroepiandrosterone (DHEA) is metabolized in human plasma was studied by column and thin-layer chromatography. The results obtained…”
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Modulation of Neurosteroid Synthesis/Accumulation by l‐Ascorbic Acid in Rat Brain Tissue: Inhibition by Selected Serotonin Antagonists by Roscetti, Gianna, Del Carmine, Renata, Trabucchi, Marco, Massotti, Marino, Purdy, Robert H., Barbaccia, Maria Luisa

“…: We have investigated the possibility that the synthesis/accumulation of neurosteroids, i.e., brain‐produced steroids putatively endowed with modulatory…”
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Maprotiline: an antidepressant with an unusual pharmacological profile by Barbaccia, M L, Ravizza, L, Costa, E

“…Maprotiline, which differs from other typical tricyclic antidepressants for its tetracyclic structure, is a highly selective inhibitor of norepinephrine…”
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Stress and neuroactive steroids by Barbaccia, M L, Serra, M, Purdy, R H, Biggio, G

“…The discovery that the endogenous steroid derivatives 3 alpha-hydroxy-5 alpha-pregnan-20-one (allopregnanolone, or 3 alpha,5 alpha-TH PROG) and 3…”
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Isoniazid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain by Barbaccia, M L, Roscetti, G, Trabucchi, M, Purdy, R H, Mostallino, M C, Perra, C, Concas, A, Biggio, G

“…Isoniazid (375 mg/kg, s.c.), a drug that decreases GABAA receptor-mediated transmission, elicited a time-dependent increase of neuroactive steroid…”
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Clozapine, but not Haloperidol, Increases Brain Concentrations of Neuroactive Steroids in the Rat by Barbaccia, Maria Luisa, Affricano, Daniela, Purdy, Robert H, Maciocco, Elisabetta, Spiga, Francesca, Biggio, Giovanni

“…The extrapyramidal side effects of typical antipsychotics, which are induced to a markedly reduced extent by clozapine, have been linked to a dysfunction of…”
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Modulation of Neuronal Serotonin Uptake by a Putative Endogenous Ligand of Imipramine Recognition Sites by Barbaccia, Maria Luisa, Gandolfi, Ottavio, Chuang, De-Maw, Costa, Erminio

“…Imipramine inhibits the serotonin uptake by binding with high affinity to regulatory sites of this uptake located on axons that release serotonin. The number…”
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GABAB receptor-mediated increase of neurosteroids by γ-hydroxybutyric acid by BARBACCIA, M. L, COLOMBO, G, AFFRICANO, D, CARAI, M. A. M, VACCA, G, MELIS, S, PURDY, R. H, GESSA, G. L

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Meet Our Editorial Board Member by Barbaccia, M L

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