Search Results - "BANE, Fiona T"

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities by Cosgrove, Nicola, Varešlija, Damir, Keelan, Stephen, Elangovan, Ashuvinee, Atkinson, Jennifer M., Cocchiglia, Sinéad, Bane, Fiona T., Singh, Vikrant, Furney, Simon, Hu, Chunling, Carter, Jodi M., Hart, Steven N., Yadav, Siddhartha, Goetz, Matthew P., Hill, Arnold D. K., Oesterreich, Steffi, Lee, Adrian V., Couch, Fergus J., Young, Leonie S.

“…The molecular events and transcriptional plasticity driving brain metastasis in clinically relevant breast tumor subtypes has not been determined. Here we…”
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NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis by LI QIN, WU, Ye-Lin, ZHIHUI YANG, YAN XU, THEISSEN, Sarah M, YI LI, YOUNG, Leonie, JIANMING XU, TONEFF, Michael J, DABING LI, LAN LIAO, XIUHUA GAO, BANE, Fiona T, TIEN, Jean C.-Y, YIXIANG XU, ZHEN FENG

“…In breast cancer, overexpression of the nuclear coactivator NCOA1 (SRC-1) is associated with disease recurrence and resistance to endocrine therapy. To examine…”
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S100β as a serum marker in endocrine resistant breast cancer by Charmsaz, Sara, Hughes, Éamon, Bane, Fiona T, Tibbitts, Paul, McIlroy, Marie, Byrne, Christopher, Cocchiglia, Sinéad, McBryan, Jean, Hennessy, Bryan T, Dwyer, Róisín M, Kerin, Michael J, Hill, Arnold D, Young, Leonie S

“…Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer. However, its efficacy is limited by intrinsic and acquired…”
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Coassociation of Estrogen Receptor and p160 Proteins Predicts Resistance to Endocrine Treatment; SRC-1 is an Independent Predictor of Breast Cancer Recurrence by REDMOND, Aisling M, BANE, Fiona T, STAFFORD, Anthony T, MCLLROY, Marie, DILLON, Mary F, CROTTY, Thomas B, HILL, Arnold D, YOUNG, Leonie S

“…Purpose: This study investigates the role of the p160 coactivators AIB1 and SRC-1 independently, and their interactions with the estrogen receptor, in the…”
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The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells by Bane, Fiona T, Bannon, John H, Pennington, Stephen R, Campiani, Giuseppe, Campaini, Giuseppe, Williams, D Clive, Zisterer, Daniela M, Mc Gee, Margaret M

“…Microtubule assembly and disassembly is required for the maintenance of cell structure, mobility, and division. However, the cellular and biochemical…”
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Altered Steroid Milieu in AI-Resistant Breast Cancer Facilitates AR Mediated Gene-Expression Associated with Poor Response to Therapy by Creevey, Laura, Bleach, Rachel, Madden, Stephen F, Toomey, Sinead, Bane, Fiona T, Varešlija, Damir, Hill, Arnold D, Young, Leonie S, McIlroy, Marie

“…Divergent roles for androgen receptor (AR) in breast cancer have been reported. Following aromatase inhibitor (AI) treatment, the conversion of circulating…”
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Comparative analysis of the AIB1 interactome in breast cancer reveals MTA2 as a repressive partner which silences E-Cadherin to promote EMT and associates with a pro-metastatic phenotype by Varešlija, Damir, Ward, Elspeth, Purcell, Siobhan P., Cosgrove, Nicola S., Cocchiglia, Sinéad, O’Halloran, Philip J., Charmsaz, Sara, Bane, Fiona T., Brett, Francesca M., Farrell, Michael, Cryan, Jane, Beausang, Alan, Hudson, Lance, Turnbul, Arran K., Dixon, J. Michael, Hill, Arnold D. K., Priedigkeit, Nolan, Oesterreich, Steffi, Lee, Adrian V., Sims, Andrew H., Redmond, Aisling M., Carroll, Jason S., Young, Leonie S.

“…Steroid regulated cancer cells use nuclear receptors and associated regulatory proteins to orchestrate transcriptional networks to drive disease progression…”
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Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy by McBryan, Jean, Fagan, Ailís, McCartan, Damian, Bane, Fiona T, Varešlija, Damir, Cocchiglia, Sinéad, Byrne, Christopher, Bolger, Jarlath, McIlroy, Marie, Hudson, Lance, Tibbitts, Paul, Gaora, Peadar Ó, Hill, Arnold D, Young, Leonie S

“…Disease recurrence is a common problem in breast cancer and yet the mechanisms enabling tumor cells to evade therapy and colonize distant organs remain…”
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Abstract P2-05-13: Transcriptomic profiling of patient sequential tumours provides cutting edge view of global metastatic expression changes following endocrine therapy by McBryan, Jean, Fagan, Ailis, McCartan, Damian, Bolger, Jarlath C, Bane, Fiona T, Byrne, Christopher, McIlroy, Marie, Hill, Arnold D, Young, Leonie S

“…Abstract Disease recurrence is a common problem in breast cancer and yet the mechanisms enabling tumour cells to evade therapy and colonise distant organs…”
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S100Beta as a serum marker in endocrine resistant breast cancer by Charmsaz, Sara, Hughes, Eamon, Bane, Fiona T, Tibbitts, Paul, McIlroy, Marie, Byrne, Christopher, Cocchiglia, Sinead, McBryan, Jean, Hennessy, Bryan T, Dwyer, Roisin M, Kerin, Michael J, Hill, Arnold D, Young, Leonie S

“…Background Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer. However, its efficacy is limited by intrinsic and…”
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