Search Results - "BALMASEDA, Angel"

Antibody-dependent enhancement of severe dengue disease in humans by Katzelnick, Leah C., Gresh, Lionel, Halloran, M. Elizabeth, Mercado, Juan Carlos, Kuan, Guillermina, Gordon, Aubree, Balmaseda, Angel, Harris, Eva

“…For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to enhance viral replication in vitro and severe disease in animal…”
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Neutralizing antibody titers against dengue virus correlate with protection from symptomatic infection in a longitudinal cohort by Katzelnick, Leah C., Montoya, Magelda, Gresh, Lionel, Balmaseda, Angel, Harris, Eva

“…The four dengue virus serotypes (DENV1–4) are mosquito-borne flaviviruses that infect ∼390 million people annually; up to 100 million infections are…”
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Obesity Increases the Duration of Influenza A Virus Shedding in Adults by Maier, Hannah E, Lopez, Roger, Sanchez, Nery, Ng, Sophia, Gresh, Lionel, Ojeda, Sergio, Burger-Calderon, Raquel, Kuan, Guillermina, Harris, Eva, Balmaseda, Angel, Gordon, Aubree

“…Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly…”
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Novel correlates of protection against pandemic H1N1 influenza A virus infection by Ng, Sophia, Nachbagauer, Raffael, Balmaseda, Angel, Stadlbauer, Daniel, Ojeda, Sergio, Patel, Mayuri, Rajabhathor, Arvind, Lopez, Roger, Guglia, Andrea F., Sanchez, Nery, Amanat, Fatima, Gresh, Lionel, Kuan, Guillermina, Krammer, Florian, Gordon, Aubree

“…Influenza viruses remain a severe threat to human health, causing up to 650,000 deaths annually 1 , 2 . Seasonal influenza virus vaccines can prevent…”
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The respiratory microbiome and susceptibility to influenza virus infection by Lee, Kyu Han, Gordon, Aubree, Shedden, Kerby, Kuan, Guillermina, Ng, Sophia, Balmaseda, Angel, Foxman, Betsy

“…Influenza is a major cause of morbidity and mortality worldwide. However, vaccine effectiveness has been low to moderate in recent years and vaccine coverage…”
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Zika virus infection enhances future risk of severe dengue disease by Katzelnick, Leah C, Narvaez, César, Arguello, Sonia, Lopez Mercado, Brenda, Collado, Damaris, Ampie, Oscarlett, Elizondo, Douglas, Miranda, Tatiana, Bustos Carillo, Fausto, Mercado, Juan Carlos, Latta, Krista, Schiller, Amy, Segovia-Chumbez, Bruno, Ojeda, Sergio, Sanchez, Nery, Plazaola, Miguel, Coloma, Josefina, Halloran, M Elizabeth, Premkumar, Lakshmanane, Gordon, Aubree, Narvaez, Federico, de Silva, Aravinda M, Kuan, Guillermina, Balmaseda, Angel, Harris, Eva

“…The Zika pandemic sparked intense interest in whether immune interactions among dengue virus serotypes 1 to 4 (DENV1 to -4) extend to the closely related Zika…”
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Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua by Gordon, Aubree, Gresh, Lionel, Ojeda, Sergio, Katzelnick, Leah C, Sanchez, Nery, Mercado, Juan Carlos, Chowell, Gerardo, Lopez, Brenda, Elizondo, Douglas, Coloma, Josefina, Burger-Calderon, Raquel, Kuan, Guillermina, Balmaseda, Angel, Harris, Eva

“…Zika virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across the Americas, in populations that have been largely exposed to dengue virus…”
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Association Between the Respiratory Microbiome and Susceptibility to Influenza Virus Infection by Tsang, Tim K, Lee, Kyu Han, Foxman, Betsy, Balmaseda, Angel, Gresh, Lionel, Sanchez, Nery, Ojeda, Sergio, Lopez, Roger, Yang, Yang, Kuan, Guillermina, Gordon, Aubree

“…Abstract Background Previous studies suggest that the nose/throat microbiome may play an important role in shaping host immunity and modifying the risk of…”
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Single-Reaction Multiplex Reverse Transcription PCR for Detection of Zika, Chikungunya, and Dengue Viruses by Waggoner, Jesse J, Gresh, Lionel, Mohamed-Hadley, Alisha, Ballesteros, Gabriela, Davila, Maria Jose Vargas, Tellez, Yolanda, Sahoo, Malaya K, Balmaseda, Angel, Harris, Eva, Pinsky, Benjamin A

“…Clinical manifestations of Zika virus, chikungunya virus, and dengue virus infections can be similar. To improve virus detection, streamline molecular…”
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Impact of pre-existing dengue immunity on human antibody and memory B cell responses to Zika by Andrade, Paulina, Gimblet-Ochieng, Ciara, Modirian, Faraz, Collins, Matthew, Cárdenas, Maritza, Katzelnick, Leah C., Montoya, Magelda, Michlmayr, Daniela, Kuan, Guillermina, Balmaseda, Angel, Coloma, Josefina, de Silva, Aravinda M., Harris, Eva

“…Little is known about enduring memory B cell (MBC) responses to Zika virus (ZIKV) and their relationship with circulating antibodies. Here we comprehensively…”
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Longitudinal Analysis of Antibody Cross-neutralization Following Zika Virus and Dengue Virus Infection in Asia and the Americas by Montoya, Magelda, Collins, Matthew, Dejnirattisai, Wanwisa, Katzelnick, Leah C, Puerta-Guardo, Henry, Jadi, Ramesh, Schildhauer, Samuel, Supasa, Piyada, Vasanawathana, Sirijitt, Malasit, Prida, Mongkolsapaya, Juthathip, de Silva, Aruna D, Tissera, Hasitha, Balmaseda, Angel, Screaton, Gavin, de Silva, Aravinda M, Harris, Eva

“…The 4 dengue virus serotypes (DENV1-4) and Zika virus (ZIKV) are related mosquito-borne flaviviruses of major importance globally. While monoclonal antibodies…”
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Evidence based community mobilization for dengue prevention in Nicaragua and Mexico (Camino Verde, the Green Way): cluster randomized controlled trial by Andersson, Neil, Nava-Aguilera, Elizabeth, Arosteguí, Jorge, Morales-Perez, Arcadio, Suazo-Laguna, Harold, Legorreta-Soberanis, José, Hernandez-Alvarez, Carlos, Fernandez-Salas, Ildefonso, Paredes-Solís, Sergio, Balmaseda, Angel, Cortés-Guzmán, Antonio Juan, Serrano de los Santos, René, Coloma, Josefina, Ledogar, Robert J, Harris, Eva

“…Objective To test whether community mobilization adds effectiveness to conventional dengue control.Design Pragmatic open label parallel group cluster…”
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The Timeline of Influenza Virus Shedding in Children and Adults in a Household Transmission Study of Influenza in Managua, Nicaragua by Ng, Sophia, Lopez, Roger, Kuan, Guillermina, Gresh, Lionel, Balmaseda, Angel, Harris, Eva, Gordon, Aubree

“…In a household transmission study in Nicaragua, children under 6 years old had a longer duration of presymptomatic influenza virus shedding than adults. The…”
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Effects of infection history on dengue virus infection and pathogenicity by Tsang, Tim K., Ghebremariam, Samson L., Gresh, Lionel, Gordon, Aubree, Halloran, M. Elizabeth, Katzelnick, Leah C., Rojas, Diana Patricia, Kuan, Guillermina, Balmaseda, Angel, Sugimoto, Jonathan, Harris, Eva, Longini, Ira M., Yang, Yang

“…The understanding of immunological interactions among the four dengue virus (DENV) serotypes and their epidemiological implications is often hampered by the…”
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Symptomatic versus inapparent outcome in repeat dengue virus infections is influenced by the time interval between infections and study year by Montoya, Magelda, Gresh, Lionel, Mercado, Juan Carlos, Williams, Katherine L, Vargas, Maria José, Gutierrez, Gamaliel, Kuan, Guillermina, Gordon, Aubree, Balmaseda, Angel, Harris, Eva

“…Four dengue virus serotypes (DENV1-4) circulate globally, causing more human illness than any other arthropod-borne virus. Dengue can present as a range of…”
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Evaluation of the traditional and revised WHO classifications of Dengue disease severity by Narvaez, Federico, Gutierrez, Gamaliel, Pérez, Maria Angeles, Elizondo, Douglas, Nuñez, Andrea, Balmaseda, Angel, Harris, Eva

“…Dengue is a major public health problem worldwide and continues to increase in incidence. Dengue virus (DENV) infection leads to a range of outcomes, including…”
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Dynamics of dengue disease severity determined by the interplay between viral genetics and serotype-specific immunity by OhAinle, Molly, Balmaseda, Angel, Macalalad, Alexander R, Tellez, Yolanda, Zody, Michael C, Saborío, Saira, Nuñez, Andrea, Lennon, Niall J, Birren, Bruce W, Gordon, Aubree, Henn, Matthew R, Harris, Eva

“…The rapid spread of dengue is a worldwide public health problem. In two clinical studies of dengue in Managua, Nicaragua, we observed an abrupt increase in…”
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Intrahost Selection Pressures Drive Rapid Dengue Virus Microevolution in Acute Human Infections by Parameswaran, Poornima, Wang, Chunling, Trivedi, Surbhi Bharat, Eswarappa, Meghana, Montoya, Magelda, Balmaseda, Angel, Harris, Eva

“…Dengue, caused by four dengue virus serotypes (DENV-1 to DENV-4), is a highly prevalent mosquito-borne viral disease in humans. Yet, selection pressures…”
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Influenza Virus Infection Induces a Narrow Antibody Response in Children but a Broad Recall Response in Adults by Meade, Philip, Kuan, Guillermina, Strohmeier, Shirin, Maier, Hannah E, Amanat, Fatima, Balmaseda, Angel, Ito, Kimihito, Kirkpatrick, Ericka, Javier, Andres, Gresh, Lionel, Nachbagauer, Raffael, Gordon, Aubree, Krammer, Florian

“…In contrast to influenza virus vaccination, natural infection induces long-lived and relatively broad immune responses. However, many aspects of the antibody…”
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Combining genotypes and T cell receptor distributions to infer genetic loci determining V(D)J recombination probabilities by Russell, Magdalena L, Souquette, Aisha, Levine, David M, Schattgen, Stefan A, Allen, E Kaitlynn, Kuan, Guillermina, Simon, Noah, Balmaseda, Angel, Gordon, Aubree, Thomas, Paul G, Matsen, 4th, Frederick A, Bradley, Philip

“…Every T cell receptor (TCR) repertoire is shaped by a complex probabilistic tangle of genetically determined biases and immune exposures. T cells combine a…”
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