Search Results - "BALIETTI, Marta"
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Effect of a Cognitive Training Program on the Platelet APP Ratio in Patients with Alzheimer's Disease
Published in International journal of molecular sciences (20-07-2020)“…In patients with Alzheimer's disease (AD), synaptic plasticity seems to be involved in cognitive improvement induced by cognitive training. The platelet…”
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The effect of late-life environmental enrichment on stress and anxiety: The role of sex and age-related differences in coping with aversive stimuli
Published in Heliyon (15-06-2024)“…Anxiety significantly diminishes the quality of life in older adults, and the drugs used for its treatment often come with risky side effects…”
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Late-onset major depressive disorder: exploring the therapeutic potential of enhancing cerebral brain-derived neurotrophic factor expression through targeted microRNA delivery
Published in Translational psychiatry (03-09-2024)“…Major depressive disorder (MDD) is a severe psychiatric condition that significantly impacts the overall quality of life. Although MDD can occur across all age…”
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Bacterial DNAemia in Alzheimer's Disease and Mild Cognitive Impairment: Association with Cognitive Decline, Plasma BDNF Levels, and Inflammatory Response
Published in International journal of molecular sciences (21-12-2022)“…Microbial dysbiosis (MD) provokes gut barrier alterations and bacterial translocation in the bloodstream. The increased blood bacterial DNA (BB-DNA) may…”
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Study of the effects of adapted Tango and multidimensional intervention in pREvention of dementia in agiNG: developing healTHy lifestyle programs (STRENGTH Project)—the experimental protocol of a prospective randomised controlled trial
Published in Aging clinical and experimental research (01-12-2020)“…Background Dementia represents a key health issue for older adults, with negative consequences on psycho-social and functional status. Treatments that…”
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Platelets in Alzheimer's disease-associated cellular senescence and inflammation
Published in Current pharmaceutical design (01-03-2013)“…Alzheimer's disease (AD) is a complex degenerative disorder of the brain, associated with a progressive cognitive decline. Age is the main risk factor with…”
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Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins
Published in Frontiers in aging neuroscience (04-04-2018)“…The molecular substrate of age-associated cognitive decline (AACD) is still elusive. Evidence indicates that AACD is related to synaptic impairment in…”
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Environmental enrichment and the aging brain: is it time for standardization?
Published in Neuroscience and biobehavioral reviews (01-08-2022)“…Aging entails a progressive decline of cognitive abilities. However, since the brain is endowed with considerable plasticity, adequate stimulation can delay or…”
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Peripheral Blood Brain-Derived Neurotrophic Factor as a Biomarker of Alzheimer’s Disease: Are There Methodological Biases?
Published in Molecular neurobiology (01-08-2018)“…Mounting evidence that alterations in brain-derived neurotrophic factor (BDNF) levels and signaling may be involved in the etiopathogenesis of Alzheimer’s…”
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Effects of ageing on the fine distribution of the circadian CLOCK protein in reticular formation neurons
Published in Histochemistry and cell biology (01-06-2007)“…Many biochemical, physiological and behavioural processes, from bacteria to human, exhibit roughly 24 h cyclic oscillations defined as circadian rhythms…”
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In aged rats, differences in spatial learning and memory influence the response to late-life Environmental Enrichment
Published in Experimental gerontology (01-04-2021)“…It has clearly been demonstrated that cognitive stimulation, physical exercise, and social engagement help counteract age-related cognitive decline. However,…”
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Chronic Aluminum Administration to Old Rats Results in Increased Levels of Brain Metal Ions and Enlarged Hippocampal Mossy Fibers
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: The effect of chronic aluminium administration (2 g/L/6 months) was investigated in the central nervous system (CNS) of old rats. The content of Al3+, Cu2+,…”
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A Ketogenic Diet Increases Succinic Dehydrogenase Activity in Aging Cardiomyocytes
Published in Annals of the New York Academy of Sciences (01-08-2009)“…Impairment of energy metabolism and an increase of reactive oxygen species (ROS) production seem to play a major role in age‐related apoptotic loss of…”
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Convergence between brain aging and Alzheimer’s disease: focus on mitochondria
Published in Mechanisms of ageing and development (01-12-2024)“…Alzheimer's disease (AD) accounts for the majority of dementia cases, with aging being the primary risk factor for developing this neurodegenerative condition…”
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Long-term visual object recognition memory in aged rats
Published in Rejuvenation research (01-04-2008)“…Aging is associated with memory impairments, but the neural bases of this process need to be clarified. To this end, behavioral protocols for memory testing…”
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Increased Mitochondrial and Nuclear Gene Expression of Cytochrome Oxidase Subunits I and IV in Neuronal Aging
Published in Annals of the New York Academy of Sciences (01-12-2004)“…: To assess the role of mitochondrial metabolic competence (MMC) in neuronal aging, quantitative immunohistochemistry of cytochrome oxidase (COX) subunits I…”
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Association between low values of mean arterial pressure and impaired cognitive performance in older patients with mild cognitive impairment: cross-sectional preliminary findings from the STRENGTH Project
Published in Aging clinical and experimental research (28-01-2024)“…Background Uncontrolled blood pressure (BP) is a risk factor for Mild Cognitive Impairment (MCI) and dementia. Aims This study examined the relationship…”
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Platelet Total PLA 2 Activity, Serum Oxidative Level, and Plasma Cu/Zn Ratio: A Vicious Cycle with a Potential Role to Monitor MCI and Alzheimer's Disease Progression
Published in Rejuvenation research (01-02-2022)“…Alzheimer's disease (AD) has no cure, mainly because of late diagnosis. Early diagnostic biomarkers are crucial. Phospholipases A (PLA ) are hydrolases with…”
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Generation and Characterization of the First Murine Model of Alzheimer's Disease with Mutated AβPP Inserted in a BALB/c Background (C.B6/J-APPswe)
Published in Journal of Alzheimer's disease (13-06-2023)“…Numerous mouse models of Alzheimer's disease (AD) are available, but all suffer from certain limitations, thus prompting further attempts. To date, no one…”
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The effect of chronic aluminum(III) administration on the nervous system of aged rats: clues to understand its suggested role in Alzheimer's disease
Published in Journal of Alzheimer's disease (01-12-2003)“…The effect of chronic aluminum intake has been investigated in the brain of aged male Wistar rats to assess the potential role of the accumulation of this…”
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