Search Results - "BALESTRINO, Maurizio"

Role of Creatine in the Heart: Health and Disease by Balestrino, Maurizio

“…Creatine is a key player in heart contraction and energy metabolism. Creatine supplementation (throughout the paper, only supplementation with creatine…”
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Presence of guanidinoacetate may compensate creatine absence and account for less statin-induced muscle damage in GAMT-deficient compared to AGAT-deficient mice by Balestrino, Maurizio, Adriano, Enrico

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Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease by Balestrino, Maurizio, Sarocchi, Matteo, Adriano, Enrico, Spallarossa, Paolo

“…Creatine is of paramount importance for maintaining and managing cellular ATP stores in both physiological and pathological states. Besides these “ergogenic”…”
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Creatine as a Candidate to Prevent Statin Myopathy by Balestrino, Maurizio, Adriano, Enrico

“…Statins prevent cardiovascular diseases, yet their use is limited by the muscle disturbances they cause. Rarely, statin-induced myopathy is autoimmune, but…”
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Cognitive impairment assessment through handwriting (COGITAT) score: a novel tool that predicts cognitive state from handwriting for forensic and clinical applications by Balestrino, Maurizio, Brugnolo, Andrea, Girtler, Nicola, Pardini, Matteo, Rizzetto, Cristiano, Alì, Paolo Alessandro, Cocito, Leonardo, Schiavetti, Irene

“…Handwriting deteriorates proportionally to the writer's cognitive state. Such knowledge is of special importance in the case of a contested will, where…”
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Selective Alteration of the Left Arcuate Fasciculus in Two Patients Affected by Creatine Transporter Deficiency by Balestrino, Maurizio, Adriano, Enrico, Alì, Paolo Alessandro, Pardini, Matteo

“…(1) Background: In hereditary creatine transporter deficiency (CTD), there is an absence of creatine in the brain and neurological symptoms are present,…”
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Lack of Epileptogenic Effects of the Creatine Precursor Guanidinoacetic Acid on Neuronal Cultures In Vitro by Poggio, Fabio, Brofiga, Martina, Tedesco, Mariateresa, Massobrio, Paolo, Adriano, Enrico, Balestrino, Maurizio

“…The creatine precursor Guanidinoacetic Acid (GAA) accumulates in the genetic deficiency of the GuanidinoAcetate Methyl Transferase (GAMT) enzyme and it is…”
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Effects of Delivering Guanidinoacetic Acid or Its Prodrug to the Neural Tissue: Possible Relevance for Creatine Transporter Deficiency by Adriano, Enrico, Salis, Annalisa, Damonte, Gianluca, Millo, Enrico, Balestrino, Maurizio

“…The creatine precursor guanidinoacetate (GAA) was used as a dietary supplement in humans with no adverse events. Nevertheless, it has been suggested that GAA…”
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Di-acetyl creatine ethyl ester, a new creatine derivative for the possible treatment of creatine transporter deficiency by Adriano, Enrico, Gulino, Maurizio, Arkel, Maria, Salis, Annalisa, Damonte, Gianluca, Liessi, Nara, Millo, Enrico, Garbati, Patrizia, Balestrino, Maurizio

“…•We ideated and synthesized di-acetyl creatine ethyl ester (DAC), a new very lipophilic creatine derivative.•In vitro, DAC countered the irreversible…”
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Request of hospital care dropped for TIA but remained stable for stroke during COVID-19 pandemic at a large Italian university hospital by Balestrino, Maurizio, Coccia, Alberto, Boffa, Alessandra Silvia, Furgani, Andrea, Bermano, Francesco, Finocchi, Cinzia, Bandettini di Poggio, Monica Laura, Malfatto, Laura, Farinini, Daniele, Schenone, Angelo

“…Reduced incidence of stroke during COVID-19 pandemic was sometimes reported. While decrease in stroke incidence and fear of patients to go to the hospitals…”
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Beyond sports: Efficacy and safety of creatine supplementation in pathological or paraphysiological conditions of brain and muscle by Balestrino, Maurizio, Adriano, Enrico

“…Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and in pathological conditions. Additionally, creatine facilitates…”
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In vitro study of uptake and synthesis of creatine and its precursors by cerebellar granule cells and astrocytes suggests some hypotheses on the physiopathology of the inherited disorders of creatine metabolism by Carducci, Claudia, Carducci, Carla, Santagata, Silvia, Adriano, Enrico, Artiola, Cristiana, Thellung, Stefano, Gatta, Elena, Robello, Mauro, Florio, Tullio, Antonozzi, Italo, Leuzzi, Vincenzo, Balestrino, Maurizio

“…The discovery of the inherited disorders of creatine (Cr) synthesis and transport in the last few years disclosed the importance of blood Cr supply for the…”
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Circulating Biomarkers in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Patients by Pescini, Francesca, MD, PhD, Donnini, Ida, MD, Cesari, Francesca, MSc, Nannucci, Serena, MD, Valenti, Raffaella, MD, Rinnoci, Valentina, MD, Poggesi, Anna, MD, PhD, Gori, Anna Maria, MSc, Giusti, Betti, MSc, Rogolino, Angela, MSc, Carluccio, Alessandra, MD, Bianchi, Silvia, PhD, Dotti, Maria Teresa, MD, Federico, Antonio, MD, Balestrino, Maurizio, MD, PhD, Adriano, Enrico, MSc, Abbate, Rosanna, MD, Inzitari, Domenico, MD, Pantoni, Leonardo, MD, PhD

“…Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited cerebral microangiopathy…”
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The Good, the Bad, and the Ugly: Not All Supplements Are Equal by Balestrino, Maurizio

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A Novel Hypothesis About Mechanisms Affecting Conduction Velocity of Central Myelinated Fibers by Adriano, Enrico, Perasso, Luisa, Panfoli, Isabella, Ravera, Silvia, Gandolfo, Carlo, Mancardi, Gianluigi, Morelli, Alessandro, Balestrino, Maurizio

“…The hypothesis that gap junctions are implicated in facilitating axonal conduction has not yet been experimentally demonstrated at the electrophysiological…”
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Systemic Administration of Mesenchymal Stem Cells Increases Neuron Survival after Global Cerebral Ischemia In Vivo (2VO) by Perasso, Luisa, Cogo, Carla Emilia, Giunti, Debora, Gandolfo, Carlo, Ruggeri, Piero, Uccelli, Antonio, Balestrino, Maurizio

“…Although many studies have shown that administration of stem cells after focal cerebral ischemia improves brain damage, very little data are available…”
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Pathophysiology of anoxic depolarization: new findings and a working hypothesis by Balestrino, Maurizio

“…Anoxic depolarization has been linked to the generation of hypoxic irreversible damage. Treatments that postpone its occurrence during hypoxia protect against…”
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Electrophysiology and biochemical analysis of cyclocreatine uptake and effect in hippocampal slices by Enrico, Adriano, Patrizia, Garbati, Luisa, Perasso, Alessandro, Parodi, Gianluigi, Lunardi, Carlo, Gandolfo, Maurizio, Balestrino

“…In in vitro mouse hippocampal slices we investigated whether cyclocreatine is capable of entering brain cells independently of the creatine transporter and if…”
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Kinetics of creatine in blood and brain after intraperitoneal injection in the rat by Perasso, Luisa, Cupello, Aroldo, Lunardi, Gian Luigi, Principato, Cristina, Gandolfo, Carlo, Balestrino, Maurizio

“…Creatine has in recent years raised the interest of the neurologist, because it has been used in children with hereditary disorders of creatine metabolism and…”
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The risks and uses of dietary supplements by Balestrino, Maurizio

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