Search Results - "BALAZS, TANIA"

Human and mouse hemoglobin association with the transgenic mouse erythrocyte membrane by Chen, Qiuying, Balazs, Tania C., Nagel, Ronald L., Hirsch, Rhoda Elison

“…Transgenic mouse models of hemoglobinopathies unravel pathophysiological mechanisms; yet the validity of the red blood cell (RBC) model of human hemoglobin…”
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Polymer Structure and Solubility of Deoxyhemoglobin S in the Presence of High Concentrations of Volume-excluding 70-kDa Dextran by Bookchin, Robert M., Balazs, Tania, Wang, Zhiping, Josephs, Robert, Lew, Virgilio L.

“…Earlier observations indicated that volume exclusion by admixed non-hemoglobin macromolecules lowered the polymer solubility (“ C sat ”) of deoxyhemoglobin…”
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Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran. Effects of non-s hemoglobins and inhibitors by Bookchin, R M, Balazs, T, Wang, Z, Josephs, R, Lew, V L

“…Earlier observations indicated that volume exclusion by admixed non-hemoglobin macromolecules lowered the polymer solubility ("Csat") of deoxyhemoglobin (Hb)…”
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Measurement of the hemoglobin concentration in deoxyhemoglobin S polymers and characterization of the polymer water compartment by Bookchin, R M, Balazs, T, Lew, V L

“…Biological polymers contain freely exchangeable water within intermolecular crevices with restricted access to large extrapolymer solutes. Our recent studies…”
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Osmotic effects of water compartments in protein polymers by Lew, V L, Balazs, T, Bookchin, R

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Composition of the hemoglobin S polymer by Bookchin, R M, Balazs, T, Lew, V L

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Ionic Strength Dependence of the Polymer Solubilities of Deoxyhemoglobin S + C and S + A Mixtures by Bookchin, Robert M., Balazs, Tania

“…Factors contributing to the clinical differences between sickle cell-hemoglobin C disease (SC) and the benign sickle cell trait (AS) include the higher…”
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Role of hybrid tetramer formation in gelation of haemoglobin S by BOOKCHIN, ROBERT M, NAGEL, RONALD L, BALAZS, TANIA

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Polymerisation of haemoglobin SA hybrid tetramers by BOOKCHIN, ROBERT M, BALAZS, TANIA, NAGEL, RONALD L, TELLEZ, ISABEL

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Hemoglobin Crete (0129 Ala → Pro): A New High-Affinity Variant Interacting With β°-and β°-Thalassemia by Maniatis, Alice, Bousios, Thalia, Nagel, Ronald L., Balazs, Tania, Ueda, Yoshihiro, Bookchin, Robert M., Maniatis, George M.

“…Hemoglobin Crete, β129 (H7) ala —► pro, is a new mutant bemoglobin (Hb) with high oxygen affinity that was discovered in a Greek family in various combinations…”
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Determinants of red cell sickling. Effects of varying pH and of increasing intracellular hemoglobin concentration by osmotic shrinkage by Bookchin, R M, Balazs, T, Landau, L C

“…The effects of varying pH and of increasing intracellular hemoglobin (Hb) concentration on red cell sickling and oxygen affinity were studied in whole blood…”
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Dehydration and delayed proton equilibria of red blood cells suspended in isosmotic phosphate buffers. Implications for studies of sickled cells by Bookchin, R M, Lew, D J, Balazs, T, Ueda, Y, Lew, V L

“…PO4 buffers isosmotic with plasma or phosphate-buffered saline solution with a substantial proportion of PO4 are often used to wash and suspend red blood cells…”
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