Search Results - "BAHR, Janice M"
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Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer
Published in PloS one (27-07-2021)“…Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are…”
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Inflammasome expression is higher in ovarian tumors than in normal ovary
Published in PloS one (01-01-2020)“…Chronic inflammation fundamentally influences cancer risk and development. A mechanism of chronic inflammation is the formation of inflammasome complexes which…”
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3
Glucose-Regulated Protein 78 Is a Potential Serum and Imaging Marker for Early Detection of Ovarian Cancer
Published in Cancers (10-02-2023)“…Understanding malignant transformation associated with ovarian cancer (OVCA) is important to establish early detection tests. This study examined whether…”
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Effects of Obesity and Metabolic Syndrome on Steroidogenesis and Folliculogenesis in the Female Ossabaw Mini-Pig
Published in PloS one (05-06-2015)“…The discrete effects of obesity on infertility in females remain undefined to date. To investigate obesity-induced ovarian dysfunction, we characterized…”
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Interleukin 16 expression changes in association with ovarian malignant transformation
Published in American journal of obstetrics and gynecology (01-03-2014)“…Objective Long-term unresolved inflammation has been suggested as a risk factor for the development of various malignancies. The goal of this study was to…”
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Polycystic Ovarian Condition May Be a Risk Factor for Ovarian Tumor Development in the Laying Hen Model of Spontaneous Ovarian Cancer
Published in Journal of immunology research (01-01-2018)“…Chronic inflammation and long-standing oxidative stress are potential predisposing factors for developing malignancies, including ovarian cancer (OVCA)…”
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Expression of CISH, an Inhibitor of NK Cell Function, Increases in Association with Ovarian Cancer Development and Progression
Published in Biomedicines (21-01-2023)“…Epithelial ovarian cancer (OVCA), a fatal malignancy of women, disseminates locally. Although NK cells mount immune responses against OVCA, tumors inhibit NK…”
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Immune cells in the normal ovary and spontaneous ovarian tumors in the laying hen (Gallus domesticus) model of human ovarian cancer
Published in PloS one (09-09-2013)“…Spontaneous ovarian cancer in chickens resembles human tumors both histologically and biochemically. The goal was to determine if there are differences in…”
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9
The luteinizing hormone surge regulates circadian clock gene expression in the chicken ovary
Published in Chronobiology international (01-02-2011)“…The molecular circadian clock mechanism is highly conserved between mammalian and avian species. Avian circadian timing is regulated at multiple oscillatory…”
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10
Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model
Published in Journal of immunology research (01-01-2016)“…Ovarian cancer (OVCA) mainly disseminates in the peritoneal cavity. Immune functions are important to prevent OVCA progression and recurrence. The mechanism of…”
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Ovarian Cancer: Applications of Chickens to Humans
Published in Annual review of animal biosciences (15-02-2022)“…The lack of preclinical models of spontaneous ovarian cancer (OVCA), a fatal gynecological malignancy, is a significant barrier to generating information on…”
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Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats
Published in American journal of physiology. Heart and circulatory physiology (01-12-2000)“…We investigated the effects of estrogen on global myocardial ischemia-reperfusion injury in rats that were ovariectomized (Ovx), sham-operated, or…”
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13
Validation of the Aging Hen (Gallus gallus domesticus) as an Animal Model for Uterine Leiomyomas1
Published in Biology of reproduction (01-10-2012)“…Uterine leiomyomas, or fibroids, are the most frequent gynecological tumors in premenopausal women with as many as 65% of women becoming clinically…”
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14
Changes in Nucleolin Expression during Malignant Transformation Leading to Ovarian High-Grade Serous Carcinoma
Published in Cancers (21-01-2023)“…Ovarian high-grade serous carcinoma (HGSC) is a fatal malignancy of women. Alterations in the expression of nuclear proteins are early steps in malignant…”
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15
Long term consumption of flaxseed enriched diet decreased ovarian cancer incidence and prostaglandin E2 in hens
Published in Gynecologic oncology (01-09-2013)“…Abstract Objective Ovarian cancer is the most lethal gynecological malignancy. Prevention may be the best approach to reduce ovarian cancer. Flaxseed is the…”
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Prevalence of antitumor antibodies in laying hen model of human ovarian cancer
Published in International journal of gynecological cancer (01-05-2009)“…Antitumor antibodies are associated with tumors in human cancers. There is relatively little information on the timing and progression of antibody response to…”
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Avian Infectious Bronchitis Virus: A Possible Cause of Reduced Fertility in the Rooster
Published in Avian diseases (01-12-2004)“…The formation of epididymal stones in the rooster epididymis is a widespread problem that has detrimental effects on sperm production and fertility. The cause…”
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Glucose-6-Phosphate Isomerase Is Necessary for Embryo Implantation in the Domestic Ferret
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2003)“…The mechanism of implantation in carnivores is poorly understood. However, a previously unidentified 60-kDa protein has been shown to be necessary for embryo…”
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My Scientific Journey: From an Agrarian Start to an Academic Setting
Published in Annual review of animal biosciences (08-02-2017)“…This article is a combination of an autobiography and a review of outstanding research done by over 70 graduate students, postdoctoral fellows, and visiting…”
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The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors
Published in Journal of ovarian research (29-07-2011)“…Study of the hen immune system led to seminal contributions to basic immunological principles. Recent studies of spontaneous ovarian cancer in the laying hen…”
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