Search Results - "BAEZA, Isabel"
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Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis
Published in The Journal of immunology (1950) (15-02-2011)“…CD4 Th cells producing the proinflammatory cytokine IL-17 (Th17) have been implicated in a number of inflammatory arthritides including the…”
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2
IL-4 role in the development of the lupus mouse model induced by non-bilayer phospholipids arrangements
Published in The Journal of immunology (1950) (01-05-2023)“…Non-bilayer phospholipids arrangements (NPAs) are lipid molecular associations that are different from the bilayer and are transient. However, if they become…”
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Effect of B-NIPOx in Experimental Trypanosoma cruzi Infection in Mice
Published in International journal of molecular sciences (25-12-2022)“…Chagas disease is caused by and represents a major public health problem, which is endemic in Latin America and emerging in the rest of the world. The two…”
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Interleukin 4 deficiency limits the development of a lupus‐like disease in mice triggered by phospholipids in a non‐bilayer arrangement
Published in Scandinavian journal of immunology (01-03-2021)“…Non‐bilayer phospholipids arrangements (NPAs) are transient molecular associations different from lipid bilayers. When they become stable, they can trigger a…”
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Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2016)“…Objective In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer cell immunoglobulin‐like receptor 3DL2 (KIR‐3DL2). The aim of this…”
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Identification and In Silico Characterization of Novel Helicobacter pylori Glucose-6-Phosphate Dehydrogenase Inhibitors
Published in Molecules (Basel, Switzerland) (16-08-2021)“…Helicobacter pylori (H. pylori) is a pathogen that can remain in the stomach of an infected person for their entire life. As a result, this leads to the…”
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Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis
Published in Molecules (Basel, Switzerland) (14-12-2022)“…Protozoan parasites, such as and , cause the most prevalent infections in humans in developing countries and provoke significant morbidity and mortality in…”
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Imidazole Carbamates as a Promising Alternative for Treating Trichomoniasis: In Vitro Effects on the Growth and Gene Expression of Trichomonas vaginalis
Published in Molecules (Basel, Switzerland) (31-05-2024)“…Metronidazole (MTZ) is the most common drug used against ( ) infections; however, treatment failures and high rates of recurrence of trichomoniasis have been…”
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9
Differential transcriptional response of plasmacytoid dendritic cells in mice with lupus
Published in The Journal of immunology (1950) (01-05-2020)“…Systemic lupus erythematosus (SLE) is an autoimmune, chronic and multi-systemic disease. SLE patients present high levels of type I IFN, which is mainly…”
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Influence of Adherence to the Mediterranean Diet and Level of Physical Activity with Liver Steatosis in People Aged > 50 Years and with a BMI > 25 kg/m2: Association with Biochemical Markers
Published in Nutrients (23-06-2024)“…Background: The main objective of this study is to determine the accuracy of different biochemical markers of hepatic steatosis and to correlate liver…”
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Liposomes Bearing Non-Bilayer Phospholipid Arrangements Induce Specific IgG Anti-Lipid Antibodies by Activating NK1.1+, CD4+ T Cells in Mice
Published in Membranes (Basel) (23-06-2022)“…Liposomes are artificial models of cellular membranes that are used as delivery systems for genes, drugs and protein antigens. We have previously used them to…”
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Anti-Lipid IgG Antibodies Are Produced via Germinal Centers in a Murine Model Resembling Human Lupus
Published in Frontiers in immunology (29-09-2016)“…Anti-lipid IgG antibodies are produced in some mycobacterial infections and in certain autoimmune diseases [such as anti-phospholipid syndrome, systemic lupus…”
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Kinetic and Molecular Docking Studies to Determine the Effect of Inhibitors on the Activity and Structure of Fused G6PD::6PGL Protein from Trichomonas vaginalis
Published in Molecules (Basel, Switzerland) (09-02-2022)“…Trichomoniasis is a sexually transmitted disease with a high incidence worldwide, affecting 270 million people. Despite the existence of a catalog of available…”
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Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia : Biochemical and In Silico Characterization of a New Druggable Target
Published in International journal of molecular sciences (15-07-2023)“…Giardiasis, which is caused by infection, is a relevant cause of morbidity and mortality worldwide. Because no vaccines are currently available to treat…”
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Differential activation of innate and adaptive lymphocytes during latent or active infection with Mycobacterium tuberculosis
Published in Microbiology and immunology (01-10-2022)“…Most individuals infected with Mycobacterium tuberculosis (Mtb) have latent tuberculosis (TB), which can be diagnosed with tests (such as the QuantiFERON‐TB…”
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Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2012)“…Objective Spondylarthritides (SpA), including ankylosing spondylitis (AS), are common inflammatory rheumatic diseases that are strongly associated with…”
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The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation
Published in Journal of leukocyte biology (01-09-2020)“…Mast cell activation through the high‐affinity IgE receptor (FcεRI) plays a central role in allergic reactions. FcεRI‐mediated activation triggers multiple…”
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Effects of Single and Double Mutants in Human Glucose-6-Phosphate Dehydrogenase Variants Present in the Mexican Population: Biochemical and Structural Analysis
Published in International journal of molecular sciences (15-04-2020)“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most frequent human enzymopathy, affecting over 400 million people globally. Worldwide, 217…”
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A Review Study of the Participation of Late Domains in Sorting and Transport of Viral Factors to Exosomes
Published in Life (Basel, Switzerland) (01-08-2023)“…Cellular communication depends heavily on the participation of vesicular systems generated by most cells of an organism. Exosomes play central roles in this…”
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Silver-pig skin nanocomposites and mesenchymal stem cells: suitable antibiofilm cellular dressings for wound healing
Published in Journal of nanobiotechnology (10-01-2018)“…Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often…”
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