Search Results - "BAERTSCHI, Alex J"

Apelin is expressed in intimal smooth muscle cells and promotes their phenotypic transition by Cardoso Dos Santos, Luís Miguel, Azar, Pascal, Brun, Cécile, König, Stéphane, Roatti, Angela, Baertschi, Alex J., Chaabane, Chiraz, Bochaton-Piallat, Marie-Luce

“…During atherosclerotic plaque formation, smooth muscle cells (SMCs) switch from a contractile/differentiated to a synthetic/dedifferentiated phenotype. We…”
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Forkhead Transcription Factors Coordinate Expression of Myocardial KATP Channel Subunits and Energy Metabolism by Philip-Couderc, Pierre, Tavares, Nadia Isidoro, Roatti, Angela, Lerch, René, Montessuit, Christophe, Baertschi, Alex J

“…Coordinate adaptation of myocyte metabolism and function is fundamental to survival of the stressed heart, but the mechanisms for this coordination remain…”
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Relative Contributions of Connexins 40 and 43 to Atrial Impulse Propagation in Synthetic Strands of Neonatal and Fetal Murine Cardiomyocytes by Beauchamp, Philippe, Yamada, Kathryn A, Baertschi, Alex J, Green, Karen, Kanter, Evelyn M, Saffitz, Jeffrey E, Kléber, André G

“…Atrial tissue expresses both connexin 40 (Cx40) and 43 (Cx43) proteins. To assess the relative roles of Cx40 and Cx43 in atrial electrical propagation, we…”
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Increased Expression of Adenosine Triphosphate-Sensitive K+ Channels in Mitral Dysfunction by Raeis-Dauvé, Véronique, PhD, Philip-Couderc, Pierre, PhD, Faggian, Giuseppe, MD, Tessari, Maddalena, MS, Roatti, Angela, MS, Milano, Aldo D., MD, Bochaton-Piallat, Marie-Luce, PhD, Baertschi, Alex J., PhD

“…Objectives The aim of this study was to test whether adenosine triphosphate-sensitive K+ (KATP) channel expression relates to mechanical and hypoxic stress…”
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Central Venous Hypoxemia Is a Determinant of Human Atrial ATP-Sensitive Potassium Channel Expression: Evidence for a Novel Hypoxia-Inducible Factor 1α-Forkhead Box Class O Signaling Pathway by Raeis, Véronique, Philip-Couderc, Pierre, Roatti, Angela, Habre, Walid, Sierra, Jorge, Kalangos, Afksendyios, Beghetti, Maurice, Baertschi, Alex J

“…ATP-sensitive potassium channels couple cell excitability to energy metabolism, thereby providing life-saving protection of stressed cardiomyocytes. The…”
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Increased expression of adenosine triphosphate-sensitive K+ channels in mitral dysfunction: mechanically stimulated transcription and hypoxia-induced protein stability? by Raeis-Dauvé, Véronique, Philip-Couderc, Pierre, Faggian, Giuseppe, Tessari, Maddalena, Roatti, Angela, Milano, Aldo D, Bochaton-Piallat, Marie-Luce, Baertschi, Alex J

“…The aim of this study was to test whether adenosine triphosphate-sensitive K(+) (KATP) channel expression relates to mechanical and hypoxic stress within the…”
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Angiotensin II and tumour necrosis factor α as mediators of ATP-dependent potassium channel remodelling in post-infarction heart failure by Isidoro Tavares, Nadia, Philip-Couderc, Pierre, Baertschi, Alex J., Lerch, René, Montessuit, Christophe

“…Aims Angiotensin II (Ang II) and tumour necrosis factor α (TNFα) are involved in the progression from compensated hypertrophy to heart failure. Here, we test…”
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Expression and function of ATP-dependent potassium channels in late post-infarction remodeling by Isidoro Tavares, Nadia, Philip-Couderc, Pierre, Papageorgiou, Irène, Baertschi, Alex J, Lerch, René, Montessuit, Christophe

“…Abstract Myocardial remodeling late after infarction is associated with increased incidence of fatal arrhythmias. Heterogeneous prolongation of the action…”
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Pore loop-mutated rat KIR6.1 and KIR6.2 suppress KATP current in rat cardiomyocytes by van Bever, Laurianne, Poitry, Serge, Faure, Cécile, Norman, Robert I, Roatti, Angela, Baertschi, Alex J

“…Cardiomyocytes express mRNA for all major subunits of ATP-sensitive potassium (K(ATP)) channels: KIR6.1, KIR6.2, SUR1A, SUR2A, and SUR2B. It has remained…”
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Differential sensitivity of atrial and ventricular KATP channels to metabolic inhibition by POITRY, Serge, VAN BEVER, Laurianne, COPPEX, Fabrice, ROATTI, Angela, BAERTSCHI, Alex J

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Intracellular targeting of truncated secretory peptides in the mammalian heart and brain by Brun, Cécile, Philip‐Couderc, Pierre, Raggenbass, Mario, Roatti, Angela, Baertschi, Alex J.

“…ABSTRACT Secretory polypeptides are vital for nervous system function, sleep, reproduction, growth, and metabolism. Ribosomes scanning the 5′‐end of mRNA…”
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Peptidyl-Glycine α-Amidating Monooxygenase Targeting and Shaping of Atrial Secretory Vesicles: Inhibition by Mutated N-Terminal ProANP and PBA by Labrador, Vénus, Brun, Cécile, König, Stéphane, Roatti, Angela, Baertschi, Alex J

“…ANP (atrial natriuretic peptide) is widely recognized as an important vasorelaxant, diuretic, and cardioprotective hormone. Little is known, however, about how…”
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Plasmalemmal KATP channels shape triggered calcium transients in metabolically impaired rat atrial myocytes by Baumann, Philippe, Poitry, Serge, Roatti, Angela, Baertschi, Alex J

“…The relative role of plasmalemmal and mitochondrial ATP-sensitive K(+) (K(ATP)) channels in calcium homeostasis of the atrium is little understood…”
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Acid Prohormone Sequence Determines Size, Shape, and Docking of Secretory Vesicles in Atrial Myocytes by Baertschi, Alex J, Monnier, Dominique, Schmidt, Uta, Levitan, Edwin S, Fakan, Stanislas, Roatti, Angela

“…ABSTRACT—How vesicles are born in the trans-Golgi network and reach their docking sites at the plasma membrane is still largely unknown and is investigated in…”
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A novel K(ATP) current in cultured neonatal rat atrial appendage cardiomyocytes by Baron, A, van Bever, L, Monnier, D, Roatti, A, Baertschi, A J

“…The functional and pharmacological properties of ATP-sensitive K(+) (K(ATP)) channels were studied in primary cultured neonatal rat atrial appendage…”
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A Novel K ATP Current in Cultured Neonatal Rat Atrial Appendage Cardiomyocytes by Baron, Anne, van Bever, Laurianne, Monnier, Dominique, Roatti, Angela, Baertschi, Alex J.

“…Abstract —The functional and pharmacological properties of ATP-sensitive K + (K ATP ) channels were studied in primary cultured neonatal rat atrial appendage…”
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Sulfonylurea receptor ligands modulate stretch-induced ANF secretion in rat atrial myocyte culture by Jiao, J H, Baumann, P, Baron, A, Roatti, A, Pence, R A, Baertschi, A J

“…Stretch-induced atrial natriuretic factor (ANF) secretion was studied in cultures of neonate atrial appendage myocytes. Stretch, applied for 40 min by…”
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Abstract 140: Nuclear Targeting Apelin Induces Phenotypic Transition of Vascular Smooth Muscle Cells by Bochaton-Piallat, Marie-Luce, Chaabane, Chiraz, Brun, Cécile, König, Stéphane, Audigier, Yves, Baertschi, Alex J

“…Abstract only Apelin, and its receptor APJ, are a peptidic system playing a crucial role in vascular diseases. However, the role of apelin in atherogenesis and…”
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Role of endothelin receptor subtypes in volume-stimulated ANF secretion by Baertschi, A J, Pedrazzini, T, Aubert, J F, Roatti, A, Pence, R A

“…The role of endothelin (ET) receptors was tested in volume-stimulated atrial natriuretic factor (ANF) secretion in conscious rats. Mean ANF responses to slow…”
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Neural Control of the Endocrine Rat Heart by Jiao, Jin-Hua, Baertschi, Alex J.

“…Although atrial stretch is the accepted stimulus for atrial natriuretic factor (ANF), in vivo studies suggest a stretch-independent, neurally induced ANF…”
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