Search Results - "BAE, O.‐N."

Identification of aldo-keto reductase (AKR7A1) and glutathione S-transferase pi (GSTP1) as novel renal damage biomarkers following exposure to mercury by Shin, Y-J, Kim, K-A, Kim, E-S, Kim, J-H, Kim, H-S, Ha, M, Bae, O-N

“…The kidney is one of the main targets for toxicity induced by xenobiotics. Sensitive detection of early impairment is critical to assess chemical-associated…”
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Doxorubicin‐induced platelet cytotoxicity: a new contributory factor for doxorubicin‐mediated thrombocytopenia by KIM, E.‐J., LIM, K.‐M., KIM, K.‐Y., BAE, O.‐N., NOH, J.‐Y., CHUNG, S.‐M., SHIN, S., YUN, Y.‐P., CHUNG, J.‐H.

“…Background: Doxorubicin (DOX) is a widely used anticancer drug for solid tumors and hematologic malignancy, but its active use is hampered by serious adverse…”
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Procoagulant and prothrombotic effects of the herbal medicine, Dipsacus asper and its active ingredient, dipsacus saponin C, on human platelets by SONG, J.‐S., LIM, K.‐M., KANG, S., NOH, J.‐Y., KIM, K., BAE, O.‐N., CHUNG, J.‐H.

“…Background:  In spite of the growing popularity of herbal medicines and natural food supplements, their effects on cardiovascular homeostasis remain largely…”
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Association of quinone-induced platelet anti-aggregation with cytotoxicity by KIM, Se-Ryun, LEE, Joo-Young, LEE, Moo-Yeol, CHUNG, Seung-Min, BAE, Ok-Nam, CHUNG, Jin-Ho

“…Various anti-platelet drugs, including quinones, are being investigated as potential treatments for cardiovascular disease because of their ability to prevent…”
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Arsenic-Induced Dysfunction in Relaxation of Blood Vessels by Lee, Moo-Yeol, Jung, Byung-In, Chung, Seung-Min, Bae, Ok-Nam, Lee, Joo-Young, Park, Jung-Duck, Yang, Ji-Sun, Lee, Hyomin, Chung, Jin-Ho

“…Several epidemiological studies have suggested that exposure to arsenic is strongly correlated with the development of cardiovascular diseases such as…”
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Inorganic Arsenite Potentiates Vasoconstriction through Calcium Sensitization in Vascular Smooth Muscle by Lee, Moo-Yeol, Lee, Young-Ho, Lim, Kyung-Min, Chung, Seung-Min, Bae, Ok-Nam, Kim, Heon, Lee, Choong-Ryeol, Park, Jung-Duck, Chung, Jin-Ho

“…Chronic exposure to arsenic is well known as the cause of cardiovascular diseases such as hypertension. To investigate the effect of arsenic on blood vessels,…”
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Menadione induces endothelial dysfunction mediated by oxidative stress and arylation by Lee, Joo-Young, Bae, Ok-Nam, Chung, Seung-Min, Lee, Moo-Yeol, Chung, Jin-Ho

“…Our previous studies showed that menadione causes endothelial dysfunction which results in decreased relaxation and increased contraction of blood vessels…”
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Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity by Jun, Eun-Ah, Lim, Kyung-Min, Kim, KeunYoung, Bae, Ok-Nam, Noh, Ji-Yoon, Chung, Kyu-Hyuck, Chung, Jin-Ho

“…Abstract Despite the wide use of silver nanoparticles (nano Ag), its toxicity still remains poorly understood. In this report, nano Ag induced an increase in…”
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ADVERSE CONSEQUENCES OF ERYTHROCYTE EXPOSURE TO MENADIONE: INVOLVEMENT OF REACTIVE OXYGEN SPECIES GENERATION IN PLASMA by Chung, Seung-Min, Lee, Joo-Young, Lee, Moo-Yoel, Bae, Ok-Nam, Chung, Jin-Ho

“…Previous studies demonstrated that menadione, a representative quinone compound, reacts nonenzymatically with thiols in plasma, resulting in the generation of…”
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Lead-Induced Procoagulant Activation of Erythrocytes through Phosphatidylserine Exposure May Lead To Thrombotic Diseases by Shin, Jung-Hun, Lim, Kyung-Min, Noh, Ji-Yoon, Bae, Ok-Nam, Chung, Seung-Min, Lee, Moo-Yeol, Chung, Jin-Ho

“…Lead (Pb) is a ubiquitous heavy metal pollutant in various environmental media, especially in food and drinking water. In human blood, about 95% of lead is…”
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Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation by Yang, Kwan Yeol, Hwang, Du Hyeong, Yousaf, Abid Mehmood, Kim, Dong Wuk, Shin, Young-Jun, Bae, Ok-Nam, Kim, Yong-Il, Kim, Jong Oh, Yong, Chul Soon, Choi, Han-Gon

“…The purpose of this study was to develop a novel silymarin-loaded solid nanoparticle system with enhanced oral bioavailability and an ability to provide…”
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Vascular smooth muscle dysfunction induced by monomethylarsonous acid (MMA super(I) super(I) super(I)): A contributing factor to arsenic-associated cardiovascular diseases by Bae, O-N, Lim, E-K, Lim, K-M, Noh, J-Y, Chung, S-M, Lee, M-Y, Yun, Y-P, Kwon, S-C, Lee, J-H, Nah, S-Y, Chung, J-H

“…While arsenic in drinking water is known to cause various cardiovascular diseases in human, exact mechanism still remains elusive. Recently,…”
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Trivalent methylated arsenical-induced phosphatidylserine exposure and apoptosis in platelets may lead to increased thrombus formation by Bae, Ok-Nam, Lim, Kyung-Min, Noh, Ji-Yoon, Chung, Seung-Min, Kim, Se-Hwan, Chung, Jin-Ho

“…Trivalent methylated metabolites of arsenic, monomethylarsonous acid (MMAIII) and dimethylarsinous acid (DMAIII), have been found highly reactive and toxic in…”
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Enhancement of Platelet Aggregation and Thrombus Formation by Arsenic in Drinking Water: A Contributing Factor to Cardiovascular Disease by Lee, Moo-Yeol, Bae, Ok-Nam, Chung, Seung-Min, Kang, Kyu-Tae, Lee, Joo-Young, Chung, Jin-Ho

“…Arsenic in drinking water is a worldwide health problem that is associated with cardiovascular disease, but the cause is currently unknown. Arsenic effects on…”
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Co-oxidation-mediated xenobiotic activation and cytotoxicity by 12-lipoxygenase in intact platelets by Lim, Kyung-Min, Kim, Jung-Sun, Bae, Ok-Nam, Noh, Ji-Yoon, Chung, Seung-Min, Chung, Ka-Young, Chung, Jin-Ho

“…Abstract Peroxidase-mediated co-oxidation process has been suggested as a major alternative pathway for xenobiotic bioactivation other than hepatic cytochrome…”
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Generation of free radical by interaction of iron with thiols in human plasma and its possible significance by Chung, Ka-Young, Lee, Seung-Jin, Chung, Seung-Min, Lee, Moo-Yeol, Bae, Ok-Nam, Chung, Jin-Ho

“…It has been reported that iron can generate reactive oxygen species (ROS) with thiols. In this study, we examined the interaction of iron with thiols in plasma…”
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Prediction of residual stress in the welding zone of dissimilar metals using data-based models and uncertainty analysis by Lim, Dong Hyuk, Bae, In Ho, Na, Man Gyun, Kim, Jin Weon

“…Since welding residual stress is one of the major factors in the generation of primary water stress-corrosion cracking (PWSCC), it is essential to examine the…”
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Antithrombotic activity of LB30057, a newly synthesized direct thrombin inhibitor by Kang, Kyu-Tae, Jung, Byoung-In, Bae, Ok-Nam, Lee, Moo-Yeol, Chung, Seung-Min, Lee, Joo-Young, Lee, Sang-Koo, Kim, In-Chul, Chung, Jin-Ho

“…An amidrazonophenylalanine derivative, LB30057, inhibits the catalytic activity of thrombin potently by interaction with the active site of thrombin, and has…”
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The roles of ATP and calcium in morphological changes and cytotoxicity induced by 1,4-benzoquinone in platelets by Lee, Sun-Ku, Chung, Seung-Min, Lee, Moo-Yoel, Lee, Joo-Young, Ok-Nam Bae, Chung, Jin-Ho

“…To understand the mechanism of 1,4-benzoquinone-induced cytotoxicity in platelets, the roles of ATP and calcium in platelet toxicity and morphological changes…”
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TEMPERATURE-DEPENDENT QUINONE CYTOTOXICITY IN PLATELETS INVOLVES ARYLATION by Kang, Young-Ah, Bae, Ok-Nam, Lee, Moo-Yeol, Chung, Seung-Min, Lee, Joo-Young, Chung, Jin-Ho

“…Menadione (MEN), a representative quinone compound, produces cytotoxicity in many cells by arylation with protein thiols and oxidative stress due to redox…”
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