Search Results - "BADIANG ALBERTI, Jennifer G"

Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding by EMMITTE, Kyle A, ADJEBANG, George M, JACKSON, Jeffrey R, KUNTZ, Kevin W, LANSING, Timothy J, MOOK, Robert A, NAILOR, Kristen E, POBANZ, Mark A, SMITH, Stephon C, SUNG, Chiu-Mei, CHEUNG, Mui, WEBB ANDREWS, C, BADIANG ALBERTI, Jennifer G, BAMBAL, Ramesh, CHAMBERLAIN, Stanley D, DAVIS-WARD, Ronda G, DICKSON, Hamilton D, HASSLER, Daniel F, HORNBERGER, Keith R

“…A series of thiophene PLK1 inhibitors was optimized for increased solubility and reduced protein binding through the appendage of basic amine functionality…”
Get full text

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines as EGFR and ErbB-2 inhibitors by Stevens, Kirk L., Alligood, Krystal J., Alberti, Jennifer G. Badiang, Caferro, Thomas R., Chamberlain, Stanley D., Dickerson, Scott H., Dickson, Hamilton D., Emerson, Holly K., Griffin, Robert J., Hubbard, Robert D., Keith, Barry R., Mullin, Robert J., Petrov, Kimberly G., Gerding, Roseanne M., Reno, Michael J., Rheault, Tara R., Rusnak, David W., Sammond, Douglas M., Smith, Stephon C., Uehling, David E., Waterson, Alex G., Wood, Edgar R.

“…A novel class of pyrrolidinyl-acetyleneic thieno[3,2- d]pyrimidines has been identified which potently inhibit the EGFR and ErbB-2 receptor tyrosine kinases…”
Get full text

Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: Potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like properties by Rheault, Tara R., Donaldson, Kelly H., Badiang-Alberti, Jennifer G., Davis-Ward, Ronda G., Andrews, C. Webb, Bambal, Ramesh, Jackson, Jeffrey R., Cheung, Mui

“…Potent inhibitors of PLK1 with acceptable solubility, mouse iv clearance, and reduced CYP450 inhibition were identified. Drug-like properties were improved…”
Get full text

Corrigendum to “Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding” [Bioorg. Med. Chem. Lett. 19 (2009) 1694] by Emmitte, Kyle A., Adjabeng, George M., Webb Andrews, C., Badiang Alberti, Jennifer G., Bambal, Ramesh, Chamberlain, Stanley D., Davis-Ward, Ronda G., Dickson, Hamilton D., Hassler, Daniel F., Hornberger, Keith R., Jackson, Jeffrey R., Kuntz, Kevin W., Lansing, Timothy J., Mook, Robert A., Nailor, Kristen E., Pobanz, Mark A., Smith, Stephon C., Sung, Chiu-Mei, Cheung, Mui

Get full text