Search Results - "BACKMAN, H"

systemPipeR: NGS workflow and report generation environment by H Backman, Tyler W, Girke, Thomas

“…Next-generation sequencing (NGS) has revolutionized how research is carried out in many areas of biology and medicine. However, the analysis of NGS data…”
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ChemMine tools: an online service for analyzing and clustering small molecules by Backman, Tyler W. H., Cao, Yiqun, Girke, Thomas

“…ChemMine Tools is an online service for small molecule data analysis. It provides a web interface to a set of cheminformatics and data mining tools that are…”
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ClusterCAD: a computational platform for type I modular polyketide synthase design by Eng, Clara H, Backman, Tyler W H, Bailey, Constance B, Magnan, Christophe, García Martín, Héctor, Katz, Leonard, Baldi, Pierre, Keasling, Jay D

“…Abstract ClusterCAD is a web-based toolkit designed to leverage the collinear structure and deterministic logic of type I modular polyketide synthases (PKSs)…”
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Previous pre‐eclampsia, gestational diabetes mellitus and the risk of cardiovascular disease: A nested case–control study in Sweden by Hildén, Karin, Magnuson, Anders, Montgomery, Scott, Schwarcz, Erik, Hanson, Ulf, Simmons, David, Backman, Helena

“…Objective Pre‐eclampsia and gestational diabetes mellitus (GDM) are two common pregnancy complications that affect birth outcomes and are associated with a…”
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Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression by Zou, Zhen, Saha, Tusar T, Roy, Sourav, Shin, Sang Woon, Backman, Tyler W H, Girke, Thomas, White, Kevin P, Raikhel, Alexander S

“…Juvenile hormone III (JH) plays a key role in regulating the reproduction of female mosquitoes. Microarray time-course analysis revealed dynamic changes in…”
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BayFlux: A Bayesian method to quantify metabolic Fluxes and their uncertainty at the genome scale by Backman, Tyler W. H, Schenk, Christina, Radivojevic, Tijana, Ando, David, Singh, Jahnavi, Czajka, Jeffrey J, Costello, Zak, Keasling, Jay D, Tang, Yinjie, Akhmatskaya, Elena, Garcia Martin, Hector

“…Metabolic fluxes, the number of metabolites traversing each biochemical reaction in a cell per unit time, are crucial for assessing and understanding cell…”
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Severe Asthma in a General Population Study: Prevalence and Clinical Characteristics by Rönnebjerg, Lina, Axelsson, Malin, Kankaanranta, Hannu, Backman, Helena, Rådinger, Madeleine, Lundbäck, Bo, Ekerljung, Linda

“…Current guidelines primarily use medication levels to distinguish severe asthma from other types of asthma. In addition, severe asthma must also be…”
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fmcsR: mismatch tolerant maximum common substructure searching in R by Wang, Yan, Backman, Tyler W H, Horan, Kevin, Girke, Thomas

“…The ability to accurately measure structural similarities among small molecules is important for many analysis routines in drug discovery and chemical…”
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Non-response did not affect prevalence estimates of asthma and respiratory symptoms - results from a postal questionnaire survey of the general population by Räisänen, P., Hedman, L., Andersson, M., Stridsman, C., Lindberg, A., Lundbäck, B., Rönmark, E., Backman, H.

“…A high participation rate is warranted in order to ensure validity in surveys of the general population. However, participation rates in such studies have…”
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Evaluation of the global lung function initiative 2012 reference values for spirometry in a Swedish population sample by Backman, Helena, Lindberg, Anne, Sovijärvi, Anssi, Larsson, Kjell, Lundbäck, Bo, Rönmark, Eva

“…The Global Lung Function Initiative 2012 (GLI) reference values are currently endorsed by several respiratory societies but evaluations of applicability for…”
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Association of Electronic Cigarette Use With Smoking Habits, Demographic Factors, and Respiratory Symptoms by Hedman, Linnea, Backman, Helena, Stridsman, Caroline, Bosson, Jenny A, Lundbäck, Magnus, Lindberg, Anne, Rönmark, Eva, Ekerljung, Linda

“…There is an ongoing debate about whether electronic cigarettes (e-cigarettes) are the solution to the tobacco epidemic or a new public health threat. Large…”
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Occupation, socioeconomic status and chronic obstructive respiratory diseases – The EpiLung study in Finland, Estonia and Sweden by Jalasto, Juuso, Lassmann-Klee, Paul, Schyllert, Christian, Luukkonen, Ritva, Meren, Mari, Larsson, Matz, Põlluste, Jaak, Sundblad, Britt-Marie, Lindqvist, Ari, Krokstad, Steinar, Kankaanranta, Hannu, Kauppi, Paula, Sovijärvi, Anssi, Haahtela, Tari, Backman, Helena, Lundbäck, Bo, Piirilä, Päivi

“…To study occupational groups and occupational exposure in association with chronic obstructive respiratory diseases. In early 2000s, structured interviews on…”
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High incidence and persistence of airborne allergen sensitization up to age 19 years by Rönmark, E., Warm, K., Bjerg, A., Backman, H., Hedman, L., Lundbäck, B.

“…Background Longitudinal population‐based studies about the natural history of allergic sensitization are rare. The aim was to study incidence and persistence…”
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The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization by Morrell, William C, Birkel, Garrett W, Forrer, Mark, Lopez, Teresa, Backman, Tyler W. H, Dussault, Michael, Petzold, Christopher J, Baidoo, Edward E. K, Costello, Zak, Ando, David, Alonso-Gutierrez, Jorge, George, Kevin W, Mukhopadhyay, Aindrila, Vaino, Ian, Keasling, Jay D, Adams, Paul D, Hillson, Nathan J, Garcia Martin, Hector

“…Although recent advances in synthetic biology allow us to produce biological designs more efficiently than ever, our ability to predict the end result of these…”
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The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism by Birkel, Garrett W, Ghosh, Amit, Kumar, Vinay S, Weaver, Daniel, Ando, David, Backman, Tyler W H, Arkin, Adam P, Keasling, Jay D, Martín, Héctor García

“…Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the…”
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Large-scale bioactivity analysis of the small-molecule assayed proteome by Backman, Tyler William H, Evans, Daniel S, Girke, Thomas

“…This study presents an analysis of the small molecule bioactivity profiles across large quantities of diverse protein families represented in PubChem BioAssay…”
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Hand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study by Strandkvist, Viktor Johansson, Backman, Helena, Röding, Jenny, Stridsman, Caroline, Lindberg, Anne

“…Cardiovascular diseases and skeletal muscle dysfunction are common comorbidities in COPD. Hand grip strength (HGS) is related to general muscle strength and is…”
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Ischemic ECG abnormalities are associated with an increased risk for death among subjects with COPD, also among those without known heart disease by Nilsson, Ulf, Blomberg, Anders, Johansson, Bengt, Backman, Helena, Eriksson, Berne, Lindberg, Anne

“…An abstract, including parts of the results, has been presented at an oral session at the European Respiratory Society International Conference, London, UK,…”
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Update of ASRP: the Arabidopsis Small RNA Project database by Backman, Tyler W.H, Sullivan, Christopher M, Cumbie, Jason S, Miller, Zachary A, Chapman, Elisabeth J, Fahlgren, Noah, Givan, Scott A, Carrington, James C, Kasschau, Kristin D

“…Development of the Arabidopsis Small RNA Project (ASRP) Database, which provides information and tools for the analysis of microRNA, endogenous siRNA and other…”
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Determinants of Severe Asthma – A Long-Term Cohort Study in Northern Sweden by Backman, Helena, Stridsman, Caroline, Hedman, Linnea, Ronnebjerg, Lina, Nwaru, Bright I, Sandstrom, Thomas, Kankaanranta, Hannu, Lindberg, Anne, Ronmark, Eva

“…Background: Risk factors for severe asthma are not well described. The aim was to identify clinical characteristics and risk factors at study entry that are…”
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