Search Results - "BACHMAN, Eric S"
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Hypothalamic Orexin Stimulates Feeding-Associated Glucose Utilization in Skeletal Muscle via Sympathetic Nervous System
Published in Cell metabolism (02-12-2009)“…Hypothalamic neurons containing orexin (hypocretin) are activated during motivated behaviors and active waking. We show that injection of orexin-A into the…”
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Ravulizumab (ALXN1210) in patients with paroxysmal nocturnal hemoglobinuria: results of 2 phase 1b/2 studies
Published in Blood advances (11-09-2018)“…Ravulizumab (ALXN1210), a humanized monoclonal antibody to complement component C5, was engineered from eculizumab to have a substantially longer terminal…”
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3
Control of Cell Growth and Survival by Enzymes of the Fatty Acid Synthesis Pathway in HCT-116 Colon Cancer Cells
Published in Clinical cancer research (15-09-2008)“…Purpose: For many tumor cells, de novo lipogenesis is a requirement for growth and survival. A considerable body of work suggests that inhibition of this…”
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4
Angiotensin-Converting Enzyme and Male Fertility
Published in Proceedings of the National Academy of Sciences - PNAS (03-03-1998)“…The angiotensin-convering enzyme (ACE; EC 3.4.15.1) gene (Ace) encodes both a somatic isozyme found in blood and several other tissues, including the…”
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5
Splenectomy normalizes hematocrit in murine polycythemia vera
Published in PloS one (30-09-2009)“…Splenic enlargement (splenomegaly) develops in numerous disease states, although a specific pathogenic role for the spleen has rarely been described. In…”
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6
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
Published in Science (American Association for the Advancement of Science) (02-08-2002)“…Excessive caloric intake is thought to be sensed by the brain, which then activates thermogenesis as a means of preventing obesity. The sympathetic nervous…”
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7
β-Adrenergic Receptors, Diet-induced Thermogenesis, and Obesity
Published in The Journal of biological chemistry (08-08-2003)Get full text
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8
A School-Based Intervention for Diabetes Risk Reduction
Published in The New England journal of medicine (28-10-2010)“…To the Editor: The HEALTHY Study Group (July 29 issue) 1 found that a school-based intervention did not result in greater decreases in overweight and obesity…”
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9
Male-female differences in fertility and blood pressure in ACE-deficient mice
Published in Nature (London) (11-05-1995)“…Angiotensin-converting enzyme (ACE) is a dipeptidyl carboxy-peptidase that generates the vasoconstricting peptide angiotensin II and inactivates the…”
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The Metabolic and Cardiovascular Effects of Hyperthyroidism Are Largely Independent of β-Adrenergic Stimulation
Published in Endocrinology (Philadelphia) (01-06-2004)“…Hyperthyroidism and states of adrenergic hyperactivity have many common clinical features, suggesting similar pathogenic mechanisms of action. The widespread…”
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11
LIK066, a Dual SGLT1/2 Inhibitor, Reduces Weight and Improves Multiple Incretin Hormones in Clinical Proof-of-Concept Studies in Obese Patients With or Without Diabetes
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Background: LIK066 is a potent dual inhibitor of SGLT1/2 (IC50: 20.6 and 0.58 nM for SGLT1 and SGLT2). We studied mechanistic effects of dual SGLT1/2…”
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12
(beta)AR signaling required for diet-induced thermogenesis and obesity resistance
Published in Science (American Association for the Advancement of Science) (02-08-2002)“…Excessive caloric intake is thought to be sensed by the brain, which then activates thermogenesis as a means of preventing obesity. The sympathetic nervous…”
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13
βAR signaling required for diet-induced thermogenesis and obesity resistance
Published in Science (American Association for the Advancement of Science) (02-08-2002)“…Excessive caloric intake is thought to be sensed by the brain, which then activates thermogenesis as a means of preventing obesity. The sympathetic nervous…”
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14
Effects of different doses of galanthamine, a long-acting acetylcholinesterase inhibitor, on memory in mice
Published in Psychopharmacology (01-01-1990)“…The effects of galanthamine, a long-acting acetylcholinesterase inhibitor, on passive avoidance and a modified Morris swim task were studied in mice. Lesions…”
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15
Developmental regulation of adult cortical morphology and behavior: an animal model for mental retardation
Published in International journal of developmental neuroscience (01-06-1994)“…The purpose of this study was to examine the behavioral performance in adult mice which, as neonates, had received lesions to cortically projecting,…”
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16
betaAR signaling required for diet-induced thermogenesis and obesity resistance
Published in Science (American Association for the Advancement of Science) (02-08-2002)“…Excessive caloric intake is thought to be sensed by the brain, which then activates thermogenesis as a means of preventing obesity. The sympathetic nervous…”
Get full text
Journal Article