Search Results - "BACH, Doris"
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Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)
Published in Lancet neurology (01-07-2011)“…Summary Background Clazosentan, an endothelin receptor antagonist, significantly and dose-dependently reduced angiographic vasospasm after aneurysmal…”
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MicroRNAs associated with the efficacy of photodynamic therapy in biliary tract cancer cell lines
Published in International journal of molecular sciences (05-11-2014)“…Photodynamic therapy (PDT) is a palliative treatment option for unresectable hilar biliary tract cancer (BTC) showing a considerable benefit for survival and…”
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Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients
Published in International journal of molecular sciences (07-12-2016)“…Extensive stromal interaction is one reason for the dismal outcome of biliary tract cancer (BTC) patients. Epithelial to mesenchymal transition (EMT) is…”
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Comprehensive analysis of alterations in the miRNome in response to photodynamic treatment
Published in Journal of photochemistry and photobiology. B, Biology (05-03-2013)“…Microarray-based analysis of miRNA expression patterns confirmed by quantitative RT–PCR provides the initial comprehensive characterisation of the miRNome in…”
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Incremental prognostic value of a novel metabolite‐based biomarker score in congestive heart failure patients
Published in ESC Heart Failure (01-10-2020)“…Aims The Cardiac Lipid Panel (CLP) is a newly discovered panel of metabolite‐based biomarkers that has shown to improve the diagnostic value of N terminal pro…”
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Predictive value of alexithymia: a prospective study in somatizing patients
Published in Psychotherapy and psychosomatics (1995)“…In the present study, the potential role of alexithymia in predicting the long-term treatment outcome was investigated prospectively in 30 patients with…”
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Biomarker‐based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo‐DHF trial
Published in European journal of heart failure (01-09-2018)“…Background Myocardial fibrosis is characterized by excessive cross‐linking and deposition of collagen type I and is involved in left ventricular stiffening and…”
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Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling
Published in Stroke (1970) (01-06-2012)“…Clazosentan, an endothelin receptor antagonist, has been shown to reduce vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). CONSCIOUS-3 assessed…”
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Predictive value of metabolomic biomarkers for cardiovascular disease risk: a systematic review and meta-analysis
Published in Biomarkers (17-02-2020)“…Background: Metabolomic analysis aids in the identification of novel biomarkers by revealing the metabolic dysregulations underlying cardiovascular disease…”
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Abstract P412: Toward A Biomarker Kit Suitable For Clinical Practice; A Novel Metabolomic Biomarker Risk Score Improves The Prognostic Value Of Cardiovascular Mortality In Elderly Congestive Heart Failure Patients
Published in Circulation (New York, N.Y.) (03-03-2020)“…Abstract only Aims: The Cardiac Lipid Panel (CLP) is a newly discovered panel of metabolite-based biomarkers that has previously shown to improve the…”
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Oral ponesimod in relapsing–remitting multiple sclerosis: a randomised phase II trial
Published in Journal of neurology, neurosurgery and psychiatry (01-11-2014)“…Objective This double-blind, placebo-controlled, dose-finding phase IIb study evaluated the efficacy and safety of ponesimod, an oral selective S1P1 receptor…”
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Supervised exercise training in patients with advanced heart failure and left ventricular assist device: A multicentre randomized controlled trial (Ex‐VAD trial)
Published in European journal of heart failure (01-12-2023)“…Aims Small studies and observations suggested that exercise training may improve peak oxygen consumption (peakVO2) in patients with advanced heart failure and…”
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Cellular mechanisms of metabolic syndrome-related atrial decompensation in a rat model of HFpEF
Published in Journal of molecular and cellular cardiology (01-02-2018)“…Heart failure (HF) with preserved ejection fraction (HFpEF) is present in about 50% of HF patients. Atrial remodeling is common in HFpEF and associated with…”
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Transcutaneous vaccination via laser microporation
Published in Journal of controlled release (10-09-2012)“…Driven by constantly increasing knowledge about skin immunology, vaccine delivery via the cutaneous route has recently gained renewed interest. Considering its…”
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Effect of a group logotherapeutic program for older adults on mental health indicators
Published in Journal of humanistic counseling (04-03-2024)“…Abstract The study aimed to evaluate a logotherapeutic program for its potential to improve mental well‐being in the elderly. Group logotherapy programs…”
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Reactivating Occupational Therapy: A Method to improve Cognitive Performance in Geriatric Patients
Published in Age and ageing (01-05-1995)“…In this prospective treatment study, the effects of two different occupational therapy strategies were compared in two samples of long-term geriatric…”
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Randomised trial of clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid hemorrhage undergoing surgical clipping (CONSCIOUS-2)
Published in Acta neurochirurgica. Supplement (01-01-2013)“…We report here results of a randomized, double-blind, placebo-controlled study ( http://www.ClinicalTrials.gov , NCT00558311) that investigated the effect of…”
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Activated hedgehog pathway is a potential target for pharmacological intervention in biliary tract cancer
Published in Molecular and cellular biochemistry (01-11-2014)“…Hedgehog (Hh) signalling contributes to carcinogenesis and represents a valid druggable target in human cancers, possibly also in biliary tract cancer (BTC)…”
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Acute Hemodynamic Effects of Single-Dose Sildenafil When Added to Established Bosentan Therapy in Patients With Pulmonary Arterial Hypertension: Results of the COMPASS-1 Study
Published in Journal of clinical pharmacology (01-11-2009)“…This study investigated the acute pharmacodynamic effects of sildenafil in patients with pulmonary arterial hypertension (PAH) and concomitant bosentan…”
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Comparative immunogenicity of a PreS/S hepatitis B vaccine in non- and low responders to conventional vaccine
Published in Vaccine (05-04-2006)“…Conventional hepatitis B vaccines do not elicit adequate antibody production in 5–10% vaccinees. This trial tests the ability of a third-generation vaccine,…”
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