Search Results - "BABIKER, A. G."

Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort by Walker, AS, Dr, Ford, D, PhD, Gilks, CF, Prof, Munderi, P, MBChB, Ssali, F, MBChB, Reid, A, MBChB, Katabira, E, Prof, Grosskurth, H, Prof, Mugyenyi, P, Prof, Hakim, J, Prof, Darbyshire, JH, Prof, Gibb, DM, Prof, Babiker, AG, Prof

“…Summary Background Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination…”
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Predictors of CD4 cell recovery following initiation of antiretroviral therapy among HIV‐1 positive patients with well‐estimated dates of seroconversion by Stirrup, OT, Copas, AJ, Phillips, AN, Gill, MJ, Geskus, RB, Touloumi, G, Young, J, Bucher, HC, Babiker, AG, Kelleher, Tony, Cooper, David, Grey, Pat, Finlayson, Robert, Bloch, Mark, Kelleher, Tony, Ramacciotti, Tim, Gelgor, Linda, Smith, Don, Zangerle, Robert, Gill, John, Lutsar, Irja, Chêne, Geneviève, Dabis, Francois, Thiebaut, Rodolphe, Costagliola, Dominique, Guiguet, Marguerite, Vanhems, Philippe, Chaix, Marie‐Laure, Ghosn, Jade, Meyer, Laurence, Boufassa, Faroudy, Hamouda, Osamah, Meixenberger, Karolin, Bannert, Norbert, Bartmeyer, Barbara, Antoniadou, Anastasia, Chrysos, Georgios, Daikos, Georgios L., Pantazis, Nikos, Katsarou, Olga, Rezza, Giovanni, Dorrucci, Maria, Monforte, Antonella, Luca, Andrea, Prins, Maria, Geskus, Ronald, Helm, Jannie, Schuitemaker, Hanneke, Sannes, Mette, Brubakk, Oddbjorn, Kran, Anne‐Marte, Rosinska, Magdalena, Muga, Roberto, Tor, Jordi, Olalla, Patricia, Cayla, Joan, Amo, Julia, Moreno, Santiago, Monge, Susana, Amo, Julia, Romero, Jorge, Pérez‐Hoyos, Santiago, Sönnerborg, Anders, Bucher, C, Günthard, Huldrych, Scherrer, Alexandra, Malyuta, Ruslan, Murphy, Gary, Porter, Kholoud, Johnson, Anne, Babiker, Abdel, Pillay, Deenan, Morrison, Charles, Salata, Robert, Mugerwa, Roy, Chipato, Tsungai, Price, Matt A., Gilmour, Jill, Kamali, Anatoli, Karita, Etienne

“…Objectives To investigate factors that predict speed of recovery and long‐term CD4 cell count in HIV‐1 seroconverters initiating combination antiretroviral…”
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Early antiretroviral treatment reduces risk of bacille Calmette-Guérin immune reconstitution adenitis by RABIE, H, VIOLARI, A, GIBB, D. M, COTTON, M. F, DUONG, T, MADHI, S. A, JOSIPOVIC, D, INNES, S, DOBBELS, E, LAZARUS, E, PANCHIA, R, BABIKER, A. G

“…SETTING: Two centres in Soweto and Cape Town, South Africa.OBJECTIVE: To assess the effects of timing of initiation of antiretroviral treatment (ART) and other…”
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Demographic and HIV‐specific characteristics of participants enrolled in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial by Sharma, S, Babiker, AG, Emery, S, Gordin, FM, Lundgren, JD, Neaton, JN, Bakowska, E, Schechter, M, Wiselka, MJ, Wolff, MJ

“…Objectives The risks and benefits of initiating antiretroviral treatment (ART) at high CD4 cell counts have not been reliably quantified. The Strategic Timing…”
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Gas exchange of root hemi-parasite Striga hermonthica and its host Sorghum bicolor under short-term soil water stress by Inoue, T, Yamauchi, Y, Eltayeb, A. H, Samejima, H, Babiker, A. G. T, Sugimoto, Y

“…The gas exchange of the upper fully expanded leaf of the root parasite Striga hermonthica and of its host Sorghum bicolor was measured under wet and dry…”
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Virological and immunological outcomes at 3 years after starting antiretroviral therapy with regimens containing non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or both in INITIO: open-label randomised trial by Yeni, P, Cooper, D A, Aboulker, J P, Babiker, A G, Carey, D, Darbyshire, J H, Floridia, M, Girard, P M, Goodall, R L, Hooker, M H, Mijch, A, Meiffredy, V, Salzberger, B

“…Antiretroviral therapy has greatly reduced HIV mortality and morbidity. However, the best sequence of regimens and implications of initial regimen for…”
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Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group by Easton, D F, Peto, J, Babiker, A G

“…We discuss the problem of describing multiple group comparisons in survival analysis using the Cox model, and in matched case-control studies. The standard…”
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Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial by Mugyenyi, P, Walker, A S, Hakim, J, Munderi, P, Gibb, D M, Kityo, C, Reid, A, Grosskurth, H, Darbyshire, J H, Ssali, F, Bray, D, Katabira, E, Babiker, A G, Gilks, C F, Kabuye, G, Nsibambi, D, Kasirye, R, Zalwango, E, Nakazibwe, M, Kikaire, B, Nassuna, G, Massa, R, Fadhiru, K, Namyalo, M, Zalwango, A, Generous, L, Khauka, P, Rutikarayo, N, Nakahima, W, Mugisha, A, Todd, J, Levin, J, Muyingo, S, Ruberantwari, A, Kaleebu, P, Yirrell, D, Ndembi, N, Lyagoba, F, Hughes, P, Aber, M, Lara, A Medina, Foster, S, Amurwon, J, Wakholi, B Nyanzi, Whitworth, J, Wangati, K, Amuron, B, Kajungu, D, Nakiyingi, J, Omony, W, Tumukunde, D, Otim, T, Kabanda, J, Musana, H, Akao, J, Kyomugisha, H, Byamukama, A, Sabiiti, J, Komugyena, J, Wavamunno, P, Mukiibi, S, Drasiku, A, Byaruhanga, R, Labeja, O, Katundu, P, Tugume, S, Awio, P, Namazzi, A, Bakeinyaga, G T, Katabira, H, Abaine, D, Tukamushaba, J, Anywar, W, Ojiambo, W, Angweng, E, Murungi, S, Haguma, W, Atwiine, S, Kigozi, J, Namale, L, Mukose, A, Mulindwa, G, Atwiine, D, Muhwezi, A, Nimwesiga, E, Barungi, G, Takubwa, J, Mwebesa, D, Kagina, G, Mulindwa, M, Ahimbisibwe, F

“…Summary Background HIV antiretroviral therapy (ART) is often managed without routine laboratory monitoring in Africa; however, the effect of this approach is…”
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Impact of missing data due to drop-outs on estimators for rates of change in longitudinal studies: a simulation study by Touloumi, G., Babiker, A. G., Pocock, S. J., Darbyshire, J. H.

“…Many cohort studies and clinical trials are designed to compare rates of change over time in one or more disease markers in several groups. One major problem…”
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Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48‐week randomized comparison with abacavir/zidovudine/lamivudine in HIV‐infected Ugandan adults with low CD4 cell counts by Munderi, P, Walker, AS, Kityo, C, Babiker, AG, Ssali, F, Reid, A, Darbyshire, JH, Grosskurth, H, Mugyenyi, P, Gibb, DM, Gilks, CF

“…Background Triple nucleoside reverse transcriptase inhibitor regimens have advantages as first‐line antiretroviral therapy (ART), avoiding hepatotoxicity and…”
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Bivariate modelling of longitudinal measurements of two human immunodeficiency type 1 disease progression markers in the presence of informative drop-outs by Pantazis, N., Touloumi, G., Walker, A. S., Babiker, A. G.

“…The main statistical problem in many epidemiological studies which involve repeated measurements of surrogate markers is the frequent occurrence of missing…”
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Report from the First EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) General Assembly meeting, 9–11 November 2017, Rome, Italy by Zangari, P, Palma, P, Cotugno, N, Rojo, P, Tagarro, A, Pepponi, I, De Rossi, A, Kuhn, L, Pahwa, S, Cameron, M, Nastouli, E, Watters, S, Marceline, AG, McCoy, LE, Persaud, D, Violari, A, Chan, M, Babiker, AG, Foster, C, Ananworanich, J, Giaquinto, C, Rossi, P

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Estimation and comparison of rates of change in longitudinal studies with informative drop-outs by Touloumi, G., Pocock, S. J., Babiker, A. G., Darbyshire, J. H.

“…Many cohort studies and clinical trials have designs which involve repeated measurements of disease markers. One problem in such longitudinal studies, when the…”
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A comparison of two methods for the estimation of precision with incomplete longitudinal data, jointly modelled with a time-to-event outcome by Touloumi, G., Babiker, A. G., Kenward, M. G., Pocock, S. J., Darbyshire, J. H.

“…Several methods for the estimation and comparison of rates of change in longitudinal studies with staggered entry and informative drop‐outs have been recently…”
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Randomization-based methods for correcting for treatment changes: examples from the Concorde trial by White, Ian R., Babiker, Abdel G., Walker, Sarah, Darbyshire, Janet H.

“…We develop analysis methods for clinical trials with time‐to‐event outcomes which correct for treatment changes during follow‐up, yet are based on comparisons…”
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Age as a determinant of survival in HIV infection by Babiker, A.G, Peto, T, Porter, K, Walker, A.S, Darbyshire, J.H

“…Age is a major determinant of mortality for many diseases including HIV infection, yet the effect of age is rarely studied directly. In this article, we review…”
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Effects of powder and aqueous extracts of Euphorbia hirta on Phelipanche ramosa germination and haustorium initiation by Abdelhalim, Tilal S., Babiker, A. G. T., Finckh, Maria R.

“…Phelipanche ramosa, a root parasitic weed, is a copious seed producer. A series of laboratory experiments was undertaken to investigate the effects of powder…”
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Determinants of survival following HIV-1 seroconversion after the introduction of HAART by Porter, Kholoud, Babiker, Abdel, Bhaskaran, Krishnan, Darbyshire, Janet, Pezzotti, Patrizio, Porter, Kholoud, Walker, A Sarah

“…Highly active antiretroviral therapy (HAART) was introduced in 1997. We aimed to assess the continuing effect of this treatment on survival and progression to…”
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A proposed charter for clinical trial data monitoring committees: helping them to do their job well by Grant, A M, Altman, D G, Babiker, A G, Campbell, M K

“…Formal monitoring of data from randomised controlled trials (RCTs) is becoming more common. Wide variation exists in the structure and organisation of data…”
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Impact of covariate omission and categorization from the Fine–Gray model in randomized-controlled trials by Bakoyannis, Giorgos, Chu, Fang-I., Babiker, Abdel G. A., Touloumi, Giota

“…In this paper, we study the statistical issues related to the omission and categorization of important covariates in the context of the Fine–Gray model in…”
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