Search Results - "BABA, Kazuhiko"
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Hydrogen Absorption Mechanism into Iron in Aqueous Solution Including Metal Cations by Laser Ablation Tests and First-principles Calculations
Published in ISIJ International (15-04-2021)“…In order to clarify the effect of metal cations (Zn2+, Mg2+, Na+) in aqueous solution on hydrogen absorption into iron, the amount of hydrogen absorption from…”
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Deschloroclozapine exhibits an exquisite agonistic effect at lower concentration compared to clozapine-N-oxide in hM3Dq expressing chemogenetically modified rats
Published in Frontiers in neuroscience (30-11-2023)“…Within the realm of chemogenetics, a particular form of agonists targeting designer receptors exclusively activated by designer drugs (DREADDs) has emerged…”
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Expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of Kamikihi-to in female rats
Published in Frontiers in pharmacology (30-08-2022)“…Hypothalamo-neurohypophysial oxytocin (OXT) plays an essential role in reproduction and in several socio-physiological functions, including stress reduction,…”
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Presynaptic glutamatergic transmission and feedback system of oxytocinergic neurons in the hypothalamus of a rat model of adjuvant arthritis
Published in Molecular pain (2020)“…The neurohypophysial hormone oxytocin (OXT) is synthesized in the hypothalamic paraventricular and supraoptic nuclei. Recently, some studies have considered…”
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Novel Gas-Liquid Interfacial Plasmas for Synthesis of Metal Nanoparticles
Published in Plasma processes and polymers (14-11-2009)“…Spatially and temporally stable gas‐liquid interfacial plasmas are created using ionic liquids as electrodes of a direct‐current (DC) discharge under a low gas…”
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Upregulation of the hypothalamo-neurohypophysial system and activation of vasopressin neurones attenuates hyperalgesia in a neuropathic pain model rat
Published in Scientific reports (29-07-2022)“…Arginine vasopressin (AVP) is a hypothalamic neurosecretory hormone well known as an antidiuretic, and recently reported to be involved in pain modulation. The…”
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Heat hypersensitivity is attenuated with altered expression level of spinal astrocytes after sciatic nerve injury in TRPV1 knockout mice
Published in Neuroscience research (01-09-2021)“…•Heat sensitivity was attenuated in TRPV1 knockout mice after partial sciatic nerve ligation.•Astrogliosis was impaired in TRPV1 knockout mice after partial…”
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The neurohypophysial oxytocin and arginine vasopressin system is activated in a knee osteoarthritis rat model
Published in Journal of neuroendocrinology (01-08-2020)“…Osteoarthritis (OA) causes chronic joint pain and significantly impacts daily activities. Hence, developing novel treatment options for OA has become an…”
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Chemogenetic activation of endogenous arginine vasopressin exerts anorexigenic effects via central nesfatin-1/NucB2 pathway
Published in The journal of physiological sciences (16-06-2021)“…We examined whether the chemogenetic activation of endogenous arginine vasopressin (AVP) affects central nesfatin-1/NucB2 neurons, using a transgenic rat line…”
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Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Published in Communications biology (05-09-2022)“…Oxytocin is involved in pain transmission, although the detailed mechanism is not fully understood. Here, we generate a transgenic rat line that expresses…”
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Acute Mono-Arthritis Activates the Neurohypophysial System and Hypothalamo-Pituitary Adrenal Axis in Rats
Published in Frontiers in endocrinology (Lausanne) (11-02-2020)“…Various types of acute/chronic nociceptive stimuli cause neuroendocrine responses such as activation of the hypothalamo-neurohypophysial [oxytocin (OXT) and…”
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Oestrogen-dependent hypothalamic oxytocin expression with changes in feeding and body weight in female rats
Published in Communications biology (05-09-2022)“…Oxytocin (OXT) is produced in the hypothalamic nuclei and secreted into systemic circulation from the posterior pituitary gland. In the central nervous system,…”
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Transient receptor potential vanilloid 1 and 4 double knockout leads to increased bone mass in mice
Published in Bone Reports (01-06-2020)“…Calcium balance is important in bone homeostasis. The transient receptor potential vanilloid (TRPV) channel is a nonselective cation channel permeable to…”
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Oxytocin‐monomeric red fluorescent protein 1 synthesis in the hypothalamus under osmotic challenge and acute hypovolemia in a transgenic rat line
Published in Physiological reports (01-09-2020)“…We generated a transgenic rat line that expresses oxytocin (OXT)‐monomeric red fluorescent protein 1 (mRFP1) fusion gene to visualize the dynamics of OXT. In…”
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Antiangiogenic cancer therapy using tumor vasculature-targeted liposomes encapsulating 3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one, SU5416
Published in Cancer letters (08-11-2008)“…Abstract Previously, we identified angiogenic vessel-homing peptide Ala-Pro-Arg-Pro-Gly (APRPG), and showed that APRPG-modified liposomes could selectively…”
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Anti‐neovascular therapy by liposomal drug targeted to membrane type‐1 matrix metalloproteinase
Published in International journal of cancer (10-01-2004)“…Because membrane type‐1 matrix metalloproteinase (MT1‐MMP) is expressed specifically on the angiogenic endothelium as well as tumor cells, an agent possessing…”
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Improvement of solubility and oral bioavailability of a poorly water-soluble drug, TAS-301, by its melt-adsorption on a porous calcium silicate
Published in Journal of pharmaceutical sciences (01-02-2002)“…The aim of the present study was to improve the solubility and oral bioavailability of a poorly water-soluble drug, 3-bis(4-methoxyphenyl)…”
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Dynamical In Situ Study of Morphological Variations on Stainless Steel in a Sour Corrosive Environment
Published in Corrosion (Houston, Tex.) (01-10-2022)“…It is still unclear how environmentally assisted cracking, especially sulfide stress cracking (SSC), is caused by corrosion and fracture behavior. In this…”
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Foreword
Published in Chemical and Pharmaceutical Bulletin (01-05-2022)Get full text
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