Search Results - "BAŞPINAR KÜÇÜK, Hatice"
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Asymmetric Brønsted Acid Catalyzed Cycloadditions-Efficient Enantioselective Synthesis of Pyrazolidines, Pyrazolines, and 1,3-Diamines from N-Acyl Hyrazones and Alkenes
Published in Angewandte Chemie International Edition (14-12-2012)“…A general, metal‐free, highly enantioselective Brønsted acid catalyzed [3+2] cycloaddition between hydrazones and alkenes has been developed that affords…”
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Cytotoxic Activity and Docking Studies of 2-arenoxybenzaldehyde N-acyl Hydrazone and 1,3,4-Oxadiazole Derivatives against Various Cancer Cell Lines
Published in Molecules (Basel, Switzerland) (27-10-2022)“…To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro…”
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Mechanism and Selectivity of N‑Triflylphosphoramide Catalyzed (3+ + 2) Cycloaddition between Hydrazones and Alkenes
Published in Journal of the American Chemical Society (01-10-2014)“…Brønsted acid catalyzed (3+ + 2) cycloadditions between hydrazones and alkenes provide a general approach to pyrazolidines. The acidity of the Brønsted acid is…”
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Transition-metal-free intramolecular Friedel-Crafts reaction by alkene activation: A method for the synthesis of some novel xanthene derivatives
Published in Beilstein journal of organic chemistry (2021)“…In this work, new derivatives (substituted 9-methyl-9-arylxanthenes) of xanthene compounds ( ) of possible biological significance were synthesized by…”
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Intramolecular Friedel–Crafts Reaction with Trifluoroacetic Acid: Synthesizing Some New Functionalized 9‑Aryl/Alkyl Thioxanthenes
Published in ACS omega (19-03-2024)“…In this study, a series of halogen-substituted thioxanthenes were synthesized because the most important and biologically active derivatives of xanthenes are…”
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New Strategy for the Synthesis of Some Valuable Chiral 1,3-Diols with High Enantiomeric Purity: New Organocatalyst, Asymmetric Aldol Reaction, and Reduction
Published in ACS omega (19-03-2024)“…Chiral 1,3-diols are highly valuable molecules used in industries such as pharmaceuticals, cosmetics, and agriculture. Therefore, in this study, a new strategy…”
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Novel N‑Acyl Hydrazone Compounds as Promising Anticancer Agents: Synthesis and Molecular Docking Studies
Published in ACS omega (06-06-2023)“…In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-oxo pentanoate with different substituted groups 1a-e, were…”
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Synthesis and biological activity of new 1,3-dioxolanes as potential antibacterial and antifungal compounds
Published in Molecules (Basel, Switzerland) (01-08-2011)“…A series of new enantiomerically pure and racemic 1,3-dioxolanes 1-8 was synthesized in good yields and short reaction times by the reaction of salicylaldehyde…”
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Detailed studies on the reduction of aliphatic 3-, 4-, 6-, and 13-oximino esters: Synthesis of novel isomeric amino esters, oximino alcohols, and amino alcohols
Published in Synthetic communications (17-11-2017)“…The preparation of novel 3-, 4-, 6-, and 13-amino-tetradecanoic acid methyl esters (2a-d) obtained by the reduction of 3-, 4-, 6-, and 13-oximino-tetradecanoic…”
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Synthesis of novel 1,2,3-thiadizoles and 1,2,3-selenadiazoles as new antimicrobial agents
Published in Phosphorus, sulfur, and silicon and the related elements (02-09-2019)“…A series of novel 1,2,3-thiadiazoles and 1,2,3-selenadiazoles having a long alkyl chain were synthesized by reacting semicarbazones with SOCl 2 and SeO 2 ,…”
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Synthesis of New Chiral and Racemic 1,3-Dioxolanes
Published in Journal of heterocyclic chemistry (01-09-2012)“…A series of chiral 1,3‐dioxolanes, 3–12, with >99% ee values, have been synthesized. This is the first study of chiral ketalization reaction starting from…”
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Practical synthesis of 2,5-disubstituted 1,3-dioxolane-4-ones and highly diastereoselective cis-2,5-disubstituted 1,3-dioxolane-4-ones from α-hydroxy acids catalyzed by N-triflylphosphoramide
Published in Tetrahedron letters (07-10-2015)“…[Display omitted] N-triflylphosphoramide (NTPA) was found to be an efficient Brønsted acid catalyst for the practical synthesis of 2,5-disubstituted…”
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Synthesis of new pyrazolidines by [3+2] cycloaddition: Anticancer, antioxidant activities, and molecular docking studies
Published in Journal of molecular structure (05-01-2024)“…•A series of novel pyrazolidine derivatives were synthesized by [3 + 2] cycloaddition.•All synthesized pyrazolidine compounds were evaluated for their…”
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Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •A new series of cylopentapyrazole bearing a 1,2,3-thiadiazole ring was designed and synthesized.•[3 + 2] cycloaddition with 4-methyl-[1,2,3]…”
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Asymmetric Synthesis of Chiral γ‐ and δ‐Amino Esters Using Trichlorosilane Activated with a Lewis Base Catalyst
Published in ChemistrySelect (Weinheim) (28-05-2020)“…Novel chiral γ‐ and δ‐ amino esters 2 a–k were synthesized by enantioselective reduction of N‐aryl γ‐ and δ‐imino esters with aryl, substituted aryl, and…”
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Enantioselective synthesis of 3-hydroxytetradecanoic acid and its methyl ester enantiomers as new antioxidants and enzyme inhibitors
Published in Monatshefte für Chemie (01-07-2013)“…Optically pure R and S enantiomers of 3-hydroxytetradecanoic acid and its methyl esters were synthesised by porcine pancreas lipase catalysed hydrolysis of…”
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Antibacterial and anti-biofilm activities of new chiral and racemic 1,3-Dioxolanes
Published in Istanbul journal of pharmacy (01-01-2015)“…We investigated the potential anti-microbial and anti-biofilm activities of previously synthesized 1,3-dioxolane derivatives against several pathogen…”
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An organocatalytic method for the synthesis of some novel xanthene derivatives by the intramolecular Friedel–Crafts reaction
Published in RSC advances (01-01-2017)“…An efficient organocatalytic method for the synthesis of new substituted 9-arylxanthenes ( 2a–2u ) starting from diarylcarbinol compounds with an arenoxy group…”
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