Hospital Surveillance of Childhood Bacterial Meningitis in Senegal and the Introduction of Haemophilus influenzae Type b Conjugate Vaccine

Bacterial meningitis is an important cause of morbidity and mortality in children living in low-resource settings. Pediatric bacterial meningitis cases < 5 years of age were identified through a regional hospital surveillance system for 3 years after introduction of routine immunization with Haem...

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Bibliographic Details
Published in:	The American journal of tropical medicine and hygiene Vol. 83; no. 6; pp. 1330 - 1335
Main Authors:	BA, Osseynou, FLEMING, Jessica A, BA, Mady, DIALLO, Ndiouga, WEISS, Noel S, DIEYE, Yakou, MUTOMBO WA MUTOMBO, Boniface, BA, Mamadou, FAFA CISSE, Moussa, GAYE DIALLO, Aissatou, SOW, Iyane, SLACK, Mary P. E, COUMBA FAYE, Pape
Format:	Journal Article
Language:	English
Published:	Deerfield, IL American Society of Tropical Medecine and Hygiene 01-12-2010 The American Society of Tropical Medicine and Hygiene
Subjects:	Anti-Bacterial Agents - therapeutic use Bacteria Bacterial diseases Bacterial diseases of the nervous system. Bacterial myositis Biological and medical sciences Child Haemophilus influenzae Haemophilus Vaccines - immunology Hospitals Human bacterial diseases Humans Infectious diseases Medical sciences Meningitis, Bacterial - drug therapy Meningitis, Bacterial - epidemiology Meningitis, Bacterial - microbiology Meningitis, Bacterial - prevention & control Neisseria meningitidis Population Surveillance Senegal - epidemiology Streptococcus pneumoniae Time Factors Vaccines, Conjugate - immunology Senegal Africa Senegal, Dakar Human Nervous system diseases Mixed vaccine Haemophilus influenzae Infection Pasteurellaceae Bacterial meningitis Surveillance Bacteriosis Bacteria Tropical medicine Hospital Child
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Summary:	Bacterial meningitis is an important cause of morbidity and mortality in children living in low-resource settings. Pediatric bacterial meningitis cases < 5 years of age were identified through a regional hospital surveillance system for 3 years after introduction of routine immunization with Haemophilus influenzae type b (Hib) conjugate vaccine in Senegal in July 2005. Cases from the national pediatric hospital were also tracked from 2002 to 2008. The regional surveillance system recorded 1,711 suspected pediatric bacterial meningitis cases. Of 214 laboratory-confirmed cases, 108 (50%) were caused by Streptococcus pneumoniae, 42 (20%) to Hib, and 13 (6%) to Neisseria meningitidis. There was a 98% reduction in the number of hospitalized Hib meningitis cases from Dakar Region in 2008 compared with 2002. The surveillance system provides important information to the Ministry of Health as they consider self-funding Hib vaccine and introducing pneumococcal vaccine.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0002-9637 1476-1645
DOI:	10.4269/ajtmh.2010.10-0346