Diospyrone, a new coumarinylbinaphthoquinone from Diospyros canaliculata (Ebenaceae): structure and antimicrobial activity

Diospyrone, a new coumarinylbinaphthoquinone from Diospyros canaliculata (Ebenaceae): structure and antimicrobial activity

A new binaphthoquinone bearing two 4-hydroxy-5-methylcoumarin-3-yl units has been isolated from the stem bark of Diospyros canaliculata De Wildeman in addition to five known compounds: lupenone, betulinic acid, gerberinol, plumbagin and canaliculatin. Their structures were established on the basis o...

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Bibliographic Details
Published in:Bulletin of the Chemical Society of Ethiopia Vol. 19; no. 1; pp. 81 - 88
Main Authors: J.G. Tangmouo, D. Lontsi, F.N. Ngounou, V. Kuete, A.L. Meli, R.N. Manfouo, H.W. Kamdem, P. Tane, V. Penlap Beng, B.L.Sondengam, J.D. Connolly
Format: Journal Article
Language:English
Published: Chemical Society of Ethiopia 01-06-2005
Subjects:
Bacteria
Diospyrone
Diospyros canaliculata
Ebenaceae
Yeasts
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Summary:A new binaphthoquinone bearing two 4-hydroxy-5-methylcoumarin-3-yl units has been isolated from the stem bark of Diospyros canaliculata De Wildeman in addition to five known compounds: lupenone, betulinic acid, gerberinol, plumbagin and canaliculatin. Their structures were established on the basis of 1D (1H, 13C and DEPT) and 2D (1H-1H COSY, HMQC and HMBC) NMR experiments. Some of the above compounds showed a significant antimicrobial activity against bacteria and yeasts.
ISSN:1011-3924
1726-801X