Search Results - "B.A. Fenerich"

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    A DEPLEÇÃO DA PROTEÍNA IRS2 RESULTA EM COMPROMETIMENTO DA DIFERENCIAÇÃO ERITROIDE E MEGACARIOCÍTICA EM MODELO MURINO

    A DEPLEÇÃO DA PROTEÍNA IRS2 RESULTA EM COMPROMETIMENTO DA DIFERENCIAÇÃO ERITROIDE E MEGACARIOCÍTICA EM MODELO MURINO by B.A. Fenerich, A.B. Alves-Silva, N.P. Fonseca, J.C. Fernandes, J.L. Coelho-Silva, T.M. Bianco, C.L.A. Silva, P.S. Scheucher, L.L. Figueiredo-Pontes, E.M. Rego, J.A. Machado-Neto, F. Traina

    Published in Hematology, Transfusion and Cell Therapy (01-11-2020)
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    PS1450 THE PHARMACOLOGICAL IGF1R‐IRS1/2 INHIBITOR OSI‐906 REDUCES ERYTHROID PROGENITORS AND INHIBITS STAT3 IN JAK2V617F KNOCKIN‐MYELOPROLIFERATIVE NEOPLASM MICE

    PS1450 THE PHARMACOLOGICAL IGF1R‐IRS1/2 INHIBITOR OSI‐906 REDUCES ERYTHROID PROGENITORS AND INHIBITS STAT3 IN JAK2V617F KNOCKIN‐MYELOPROLIFERATIVE NEOPLASM MICE by Fernandes, J.C., Fenerich, B.A., Coelho‐Silva, J.L., Silva, A.B. Alves, Scheucher, P.S., Chahud, F., Rego, E.M., Figueiredo‐Pontes, L.L., Machado‐Neto, J.A., Traina, F.

    Published in HemaSphere (01-06-2019)
    “…Background: The recurrent V617F mutation in JAK2 confers growth factor‐independent proliferation for hematopoietic cells and plays an important role in the…”
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