Search Results - "Będzińska, Agnieszka"
-
1
Strong activation of p53 by actinomycin D and nutlin-3a overcomes the resistance of cancer cells to the pro-apoptotic activity of the FAS ligand
Published in Apoptosis (London) (01-10-2024)“…The FAS ligand (FASLG) is expressed on lymphocytes, which employ it to activate death receptors on target cells. Cancer cells are generally resistant to…”
Get full text
Journal Article -
2
Klotho-mediated changes in the expression of Atg13 alter formation of ULK1 complex and thus initiation of ER- and Golgi-stress response mediated autophagy
Published in Apoptosis (London) (01-02-2020)“…In the previous paper of our group, we have demonstrated that one of the crucial factors involved in the crosstalk between autophagy and apoptosis is klotho…”
Get full text
Journal Article -
3
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes
Published in Chemico-biological interactions (01-04-2024)“…Transcriptomic analyses have revealed hundreds of p53-regulated genes; however, these studies used a limited number of cell lines and p53-activating agents…”
Get full text
Journal Article -
4
The Strong Activation of p53 Tumor Suppressor Drives the Synthesis of the Enigmatic Isoform of DUSP13 Protein
Published in Biomedicines (28-06-2024)“…The p53 tumor suppressor protein activates various sets of genes depending on its covalent modifications, which are controlled by the nature and intensity of…”
Get full text
Journal Article -
5
Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes
Published in Cells (Basel, Switzerland) (21-01-2020)“…Immunosenescence in monocytes has been shown to be associated with several biochemical and functional changes, including development of senescence-associated…”
Get full text
Journal Article