Search Results - "Büttner, H"

Ultrahigh-Throughput ESI-MS: Sampling Pushed to Six Samples per Second by Acoustic Ejection Mass Spectrometry by Häbe, Tim T, Liu, Chang, Covey, Tom R, Simon, Roman P, Reindl, Wolfgang, Büttner, Frank H, Winter, Martin, Bischoff, Daniel, Luippold, Andreas H, Runge, Frank

“…We present an acoustic ejection mass spectrometry (AEMS) setup for contactless electrospray ionization mass spectrometry (ESI-MS)-based sample injection at a…”
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Advances in high‐throughput mass spectrometry in drug discovery by Dueñas, Maria Emilia, Peltier‐Heap, Rachel E, Leveridge, Melanie, Annan, Roland S, Büttner, Frank H, Trost, Matthias

“…High‐throughput (HT) screening drug discovery, during which thousands or millions of compounds are screened, remains the key methodology for identifying active…”
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The petrogenesis of highly fractionated gem-bearing pegmatites of Malawi: evidence from mica and tourmaline chemistry and finite step trace element modelling by Chakraborty, Tuhin, Büttner, Steffen H., Costin, Gelu, Kankuzi, Charles F.

“…Late-Pan-African granitic pegmatites in Malawi host gem mineralization (tourmaline, beryl/aquamarine/heliodor). We use major and trace element chemistry of…”
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Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays by Gerstberger, Thomas, Berger, Helmut, Büttner, Frank H., Gmachl, Michael, Kessler, Dirk, Koegl, Manfred, Lucas, Simon, Martin, Laetitia J., Mayer, Moriz, McConnell, Darryl B., Mitzner, Sophie, Scholz, Guido, Treu, Matthias, Wolkerstorfer, Bernhard, Zahn, Stephan, Zak, Krzysztof M., Jaeger, Philipp A., Ettmayer, Peter

“…Identifying promising chemical starting points for small molecule inhibitors of active, GTP-loaded KRAS “on” remains of great importance to clinical oncology…”
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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule by Tautermann, Christofer S, Binder, Florian, Büttner, Frank H, Eickmeier, Christian, Fiegen, Dennis, Gross, Ulrike, Grundl, Marc A, Heilker, Ralf, Hobson, Scott, Hoerer, Stefan, Luippold, Andreas, Mack, Volker, Montel, Florian, Peters, Stefan, Bhattacharya, Supriyo, Vaidehi, Nagarajan, Schnapp, Gisela, Thamm, Sven, Zeeb, Markus

“…Protein tyrosine phosphatase non-receptor type 5 (PTPN5, STEP) is a brain specific phosphatase that regulates synaptic function and plasticity by modulation of…”
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Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism by Dahms, Sven O, Schnapp, Gisela, Winter, Martin, Büttner, Frank H, Schlepütz, Marco, Gnamm, Christian, Pautsch, Alexander, Brandstetter, Hans

“…Inhibitors of the proprotein convertase furin might serve as broad-spectrum antiviral therapeutics. High cellular potency and antiviral activity against acute…”
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Tolerance of clinical vancomycin-resistant Enterococcus faecium isolates against UV-C light from a mobile source by Knobling, B, Franke, G, Belmar Campos, C, Büttner, H, Christner, M, Klupp, E M, Maurer, P M, Knobloch, J K

“…Admission to a room previously occupied by patients carrying environmentally robust pathogens implies an increased risk of acquiring those pathogens…”
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Living phosphatic stromatolites in a low‐phosphorus environment: Implications for the use of phosphorus as a proxy for phosphate levels in paleo‐systems by Büttner, Steffen H., Isemonger, Eric W., Isaacs, Michelle, Niekerk, Deon, Sipler, Rachel E., Dorrington, Rosemary A.

“…In the geological record, fossil phosphatic stromatolites date back to the Great Oxidation Event in the Paleoproterozoic, but living phosphatic stromatolites…”
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Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates by Klupp, E.-M., Both, A., Belmar Campos, C., Büttner, H., König, C., Christopeit, M., Christner, M., Aepfelbacher, M., Rohde, H.

“…Vancomycin-resistant enterococci (VRE) are of ever-increasing importance, most notably in high-risk patient populations. Therapy options are often limited for…”
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Rock Maker: an MS Excel™ spreadsheet for the calculation of rock compositions from proportional whole rock analyses, mineral compositions, and modal abundance by Büttner, Steffen H.

“…Rock Maker is a simple software tool that computes bulk rock compositions resulting from mixing or unmixing of rocks or minerals. The calculations describe the…”
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Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitors by Winter, Martin, Simon, Roman P., Wang, Yuting, Bretschneider, Tom, Bauer, Margit, Magarkar, Aniket, Reindl, Wolfgang, Fernández-Montalván, Amaury, Montel, Florian, Büttner, Frank H.

“…Recent advances in label-free high-throughput screening via matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) offer…”
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MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein-Ligand Interactions at High Throughput by Simon, Roman P, Winter, Martin, Kleiner, Carola, Wehrle, Lucie, Karnath, Michael, Ries, Robert, Zeeb, Markus, Schnapp, Gisela, Fiegen, Dennis, Häbe, Tim T, Runge, Frank, Bretschneider, Tom, Luippold, Andreas H, Bischoff, Daniel, Reindl, Wolfgang, Büttner, Frank H

“…Demonstration of in vitro target engagement for small-molecule ligands by measuring binding to a molecular target is an established approach in early drug…”
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Polar-Soft-Mode-Driven Structural Phase Transition in SrTiO3 by Bussmann-Holder, A, Büttner, H, Bishop, A R

“…The structural phase transition of SrTiO3 at 105 K, which has been believed to be independent of the ferroelectric soft mode [Phys. Rev. 177, 858 (1969)], is…”
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A novel process to separate submicron particles from gases — a cascade of packed columns by Heidenreich, S, Vogt, U, Büttner, H, Ebert, F

“…A novel process using a cascade of packed columns to separate submicron particles from gases with high efficiency is presented. The process is based on the…”
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New constraints on archetypal South African kimberlite petrogenesis from quenched glass-rich melt inclusions in olivine megacrysts by Howarth, Geoffrey H., Büttner, Steffen H.

“…The evaluation of primary kimberlite compositions is hindered by significant melt modifications during ascent through the lithosphere by entrainment of…”
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Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation by Hou, Wu-Shiun, Li, Zhenqiang, Büttner, Frank H, Bartnik, Eckart, Brömme, Dieter

“…Cathepsin K is a potent extracellular matrix-degrading protease that requires interactions with soluble glycosaminolycans for its collagenolytic activity in…”
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Chronische Koronarverschlüsse: Wann und wie revaskularisieren? by Mashayekhi, K., Büttner, H. J.

“…Zusammenfassung Chronische Koronarverschlüsse („chronic total occlusions“, CTO) liegen bei rund 20 % der PCI (perkutane Koronarintervention)-Patienten und bei…”
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Correction to: The petrogenesis of highly fractionated gem‑bearing pegmatites of Malawi: evidence from mica and tourmaline chemistry and finite step trace element modelling by Chakraborty, Tuhin, Büttner, Steffen H., Costin, Gelu, Kankuzi, Charles F.

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Retrograde Recanalization of Chronic Total Occlusions in Europe: Procedural, In-Hospital, and Long-Term Outcomes From the Multicenter ERCTO Registry by Galassi, Alfredo R, Sianos, Georgios, Werner, Gerald S, Escaned, Javier, Tomasello, Salvatore D, Boukhris, Marouane, Castaing, Marine, Büttner, Joachim H, Bufe, Alexander, Kalnins, Artis, Spratt, James C, Garbo, Roberto, Hildick-Smith, David, Elhadad, Simon, Gagnor, Andrea, Lauer, Bernward, Bryniarski, Leszek, Christiansen, Evald H, Thuesen, Leif, Meyer-Geßner, Markus, Goktekin, Omer, Carlino, Mauro, Louvard, Yves, Lefèvre, Thierry, Lismanis, Aigars, Gelev, Valery L, Serra, Antonio, Marzà, Francesco, Di Mario, Carlo, Reifart, Nicolaus

“…A retrograde approach improves the success rate of percutaneous coronary interventions (PCIs) for chronic total occlusions (CTOs). The authors describe the…”
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Phase diagram of an asymmetric spin ladder by Chen, S, Büttner, H, Voit, J

“…We investigate an asymmetric zigzag spin ladder with different exchange integrals on both legs using bosonization and renormalization group approaches. When…”
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