Search Results - "Büscher, Dirk"

Risk of tumorigenicity in mesenchymal stromal cell–based therapies—Bridging scientific observations and regulatory viewpoints by Barkholt, Lisbeth, Flory, Egbert, Jekerle, Veronika, Lucas-Samuel, Sophie, Ahnert, Peter, Bisset, Louise, Büscher, Dirk, Fibbe, Willem, Foussat, Arnaud, Kwa, Marcel, Lantz, Olivier, Mačiulaitis, Romaldas, Palomäki, Tiina, Schneider, Christian K, Sensebé, Luc, Tachdjian, Gérard, Tarte, Karin, Tosca, Lucie, Salmikangas, Paula

“…Abstract In the past decade, the therapeutic value of mesenchymal stromal cells (MSCs) has been studied in various indications, thereby taking advantage of…”
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Requirement of IFN-gamma-mediated indoleamine 2,3-dioxygenase expression in the modulation of lymphocyte proliferation by human adipose-derived stem cells by DelaRosa, Olga, Lombardo, Eleuterio, Beraza, Aitor, Mancheño-Corvo, Pablo, Ramirez, Cristina, Menta, Ramón, Rico, Laura, Camarillo, Eva, García, Laura, Abad, José Luis, Trigueros, Cesar, Delgado, Mario, Büscher, Dirk

“…Human adipose-derived mesenchymal stem cells (hASCs) are mesenchymal stem cells (MSCs) with reduced immunogenicity and capability to modulate immune responses…”
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Generation of recombinant hyperimmune globulins from diverse B-cell repertoires by Keating, Sheila M., Mizrahi, Rena A., Adams, Matthew S., Asensio, Michael A., Benzie, Emily, Carter, Kyle P., Chiang, Yao, Edgar, Robert C., Gautam, Bishal K., Gras, Ashley, Leong, Jackson, Leong, Renee, Lim, Yoong Wearn, Manickam, Vishal A., Medina-Cucurella, Angelica V., Niedecken, Ariel R., Saini, Jasmeen, Simons, Jan Fredrik, Spindler, Matthew J., Stadtmiller, Kacy, Tinsley, Brendan, Wagner, Ellen K., Wayham, Nicholas, Tracy, LaRee, Lundberg, Carina Vingsbo, Büscher, Dirk, Terencio, Jose Vicente, Roalfe, Lucy, Pearce, Emma, Richardson, Hayley, Goldblatt, David, Ramjag, Anushka T., Carrington, Christine V. F., Simmons, Graham, Muench, Marcus O., Chamow, Steven M., Monroe, Bryan, Olson, Charles, Oguin, Thomas H., Lynch, Heather, Jeanfreau, Robert, Mosher, Rachel A., Walch, Matthew J., Bartley, Christopher R., Ross, Carl A., Meyer, Everett H., Adler, Adam S., Johnson, David S.

“…Plasma-derived polyclonal antibody therapeutics, such as intravenous immunoglobulin, have multiple drawbacks, including low potency, impurities, insufficient…”
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Toll-like receptor-mediated signaling in human adipose-derived stem cells: implications for immunogenicity and immunosuppressive potential by Lombardo, Eleuterio, DelaRosa, Olga, Mancheño-Corvo, Pablo, Menta, Ramón, Ramírez, Cristina, Büscher, Dirk

“…Human adipose-derived stem cells (hASCs) are mesenchymal stem cells with reduced immunogenicity and the capability to modulate immune responses. These…”
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Activation of Notch Signaling Pathway Precedes Heart Regeneration in Zebrafish by Raya, Ángel, Koth, Christopher M., Büscher, Dirk, Kawakami, Yasuhiko, Itoh, Tohru, Raya, R. Marina, Sternik, Gabriel, Tsai, Huai-Jen, Rodríguez-Esteban, Concepción, Izpisúa-Belmonte, Juan Carlos

“…Several vertebrates display the ability to regenerate parts of their body after amputation. During this process, differentiated cells reenter the cell cycle…”
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Intralymphatic Administration of Adipose Mesenchymal Stem Cells Reduces the Severity of Collagen-Induced Experimental Arthritis by Mancheño-Corvo, Pablo, Lopez-Santalla, Mercedes, Menta, Ramon, DelaRosa, Olga, Mulero, Francisca, Del Rio, Borja, Ramirez, Cristina, Büscher, Dirk, Bueren, Juan A, Lopez-Belmonte, Juan, Dalemans, Wilfried, Garin, Marina I, Lombardo, Eleuterio

“…Mesenchymal stem cells (MSCs) are multipotent stromal cells with immunomodulatory properties. They have emerged as a very promising treatment for autoimmunity…”
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Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis by Lopez-Santalla, Mercedes, Mancheño-Corvo, Pablo, Escolano, Amelia, Menta, Ramon, DelaRosa, Olga, Abad, Jose Luis, Büscher, Dirk, Redondo, Juan M, Bueren, Juan A, Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I

“…Mesenchymal stem cells (MSCs) have a large potential in cell therapy for treatment of inflammatory and autoimmune diseases, thanks to their immunomodulatory…”
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Notch activity acts as a sensor for extracellular calcium during vertebrate left-right determination by Izpisúa Belmonte, Juan Carlos, Raya, Ángel, Kawakami, Yasuhiko, Rodríguez-Esteban, Concepción, Ibañes, Marta, Rasskin-Gutman, Diego, Rodríguez-León, Joaquín, Büscher, Dirk, Feijó, José A

“…During vertebrate embryo development, the breaking of the initial bilateral symmetry is translated into asymmetric gene expression around the node and/or in…”
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Endoscopic submucosal injection of adipose-derived mesenchymal stem cells ameliorates TNBS-induced colitis in rats and prevents stenosis by Martín Arranz, Eduardo, Martín Arranz, María Dolores, Robredo, Tomás, Mancheño-Corvo, Pablo, Menta, Ramón, Alves, Francisco Javier, Suárez de Parga, Jose Manuel, Mora Sanz, Pedro, de la Rosa, Olga, Büscher, Dirk, Lombardo, Eleuterio, de Miguel, Fernando

“…Mesenchymal stem cells have potential applications in inflammatory bowel disease due to their immunomodulatory properties. Our aim was to evaluate the…”
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MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb by Izpisúa Belmonte, Juan Carlos, Kawakami, Yasuhiko, Rodríguez-León, Joaquín, Koth, Christopher M, Büscher, Dirk, Itoh, Tohru, Raya, Ángel, Ng, Jennifer K, Esteban, Concepción Rodríguez, Takahashi, Shigeru, Henrique, Domingos, Schwarz, May-Fun, Asahara, Hiroshi

“…The mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) and phosphatidylinositol-3-OH kinase (PI3K)/Akt pathways are involved in…”
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Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling by Ribeiro, Inês, Kawakami, Yasuhiko, Büscher, Dirk, Raya, Angel, Rodríguez-León, Joaquín, Morita, Masanobu, Rodríguez Esteban, Concepción, Izpisúa Belmonte, Juan Carlos

“…The heart forms from a linear tube that is subject to complex remodeling during embryonic development. Hallmarks of this remodeling are the looping of the…”
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Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos by Raya, Angel, Kawakami, Yasuhiko, Rodriguez-Esteban, Concepcion, Buscher, Dirk, Koth, Christopher M, Itoh, Tohru, Morita, Masanobu, Raya, R Marina, Dubova, Ilir, Bessa, Joaquin Grego, de la Pompa, Jose Luis, Izpisua Belmonte, Juan Carlos

“…Left-sided expression of Nodal in the lateral plate mesoderm is a conserved feature necessary for the establishment of normal left-right asymmetry during…”
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The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10 by Ng, J K, Kawakami, Y, Buescher, D, Raya, A, Itoh, T, Koth, C M, Rodriguez-Esteban, C, Rodriguez-Leon, J, Garrity, D M, Fishman, M C, Belmonte, JCI

“…A major gap in our knowledge of development is how the growth and identity of tissues and organs are linked during embryogenesis. The vertebrate limb is one of…”
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Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression by Suzuki, Atsushi, Sekiya, Sayaka, Büscher, Dirk, Izpisúa Belmonte, Juan Carlos, Taniguchi, Hideki

“…Although the T-box family of transcription factors function in many different tissues, their role in liver development is unknown. Here we show that Tbx3 , the…”
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The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development by Takahashi, M, Tamura, K, Büscher, D, Masuya, H, Yonei-Tamura, S, Matsumoto, K, Naitoh-Matsuo, M, Takeuchi, J, Ogura, K, Shiroishi, T, Ogura, T, Izpisúa Belmonte, J C

“…We have determined that Strong's Luxoid (lstJ) [corrected] mice have a 16 bp deletion in the homeobox region of the Alx-4 gene. This deletion, which leads to a…”
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Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses by González, Manuel A, Gonzalez–Rey, Elena, Rico, Laura, Büscher, Dirk, Delgado, Mario

“…Background & Aims Crohn's disease is a chronic disease characterized by severe T-helper (Th)1 cell–driven inflammation of the colon partially caused by a loss…”
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Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses by González, Manuel A., Gonzalez–Rey, Elena, Rico, Laura, Büscher, Dirk, Delgado, Mario

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Expression profile ofGli family members andShh in normal and mutant mouse limb development by Büscher, Dirk, Rüther, Ulrich

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Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development by Büscher, Dirk, Bosse, Birgit, Heymer, Joachim, Rüther, Ulrich

“…Sonic hedgehog ( Shh) expression in the developing limb is associated with the zone of polarising activity (ZPA), and both are restricted to the posterior part…”
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Human progenitor cells derived from cardiac adipose tissue ameliorate myocardial infarction in rodents by Bayes-Genis, Antoni, Soler-Botija, Carolina, Farré, Jordi, Sepúlveda, Pilar, Raya, Angel, Roura, Santiago, Prat-Vidal, Cristina, Gálvez-Montón, Carolina, Montero, José Anastasio, Büscher, Dirk, Belmonte, Juan Carlos Izpisúa

“…Abstract Myocardial infarction caused by vascular occlusion results in the formation of nonfunctional fibrous tissue. Cumulative evidence indicates that cell…”
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