Search Results - "Bönisch, Clemens"

JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions by Procida, Tara, Friedrich, Tobias, Jack, Antonia P M, Peritore, Martina, Bönisch, Clemens, Eberl, H Christian, Daus, Nadine, Kletenkov, Konstantin, Nist, Andrea, Stiewe, Thorsten, Borggrefe, Tilman, Mann, Matthias, Bartkuhn, Marek, Hake, Sandra B

“…Histone variants differ in amino acid sequence, expression timing and genomic localization sites from canonical histones and convey unique functions to…”
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The histone variant H2A.Bbd is enriched at sites of DNA synthesis by Sansoni, Viola, Casas-Delucchi, Corella S, Rajan, Malini, Schmidt, Andreas, Bönisch, Clemens, Thomae, Andreas W, Staege, Martin S, Hake, Sandra B, Cardoso, M Cristina, Imhof, Axel

“…Histone variants play an important role in shaping the mammalian epigenome and their aberrant expression is frequently observed in several types of cancer…”
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Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y by Wiedemann, Sonja M, Mildner, Silke N, Bönisch, Clemens, Israel, Lars, Maiser, Andreas, Matheisl, Sarah, Straub, Tobias, Merkl, Rainer, Leonhardt, Heinrich, Kremmer, Elisabeth, Schermelleh, Lothar, Hake, Sandra B

“…Nucleosomal incorporation of specialized histone variants is an important mechanism to generate different functional chromatin states. Here, we describe the…”
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Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines by Horsch, Marion, Aguilar-Pimentel, Juan Antonio, Bönisch, Clemens, Côme, Christophe, Kolster-Fog, Cathrine, Jensen, Klaus T, Lund, Anders H, Lee, Icksoo, Grossman, Lawrence I, Sinkler, Christopher, Hüttemann, Maik, Bohn, Erwin, Fuchs, Helmut, Ollert, Markus, Gailus-Durner, Valérie, de Angelis, Martin Hrabĕ, Beckers, Johannes

“…We established a selection strategy to identify new models for an altered airway inflammatory response from a large compendium of mutant mouse lines that were…”
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Histone H2A variants in nucleosomes and chromatin: more or less stable? by Bönisch, Clemens, Hake, Sandra B

“…In eukaryotes, DNA is organized together with histones and non-histone proteins into a highly complex nucleoprotein structure called chromatin, with the…”
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Vererbung von Merkmalen außerhalb der primären Sequenz der DNA by Bönisch, Clemens, Huypens, Peter, Beckers, Johannes

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H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements by Zink, Lisa-Maria, Delbarre, Erwan, Eberl, H Christian, Keilhauer, Eva C, Bönisch, Clemens, Pünzeler, Sebastian, Bartkuhn, Marek, Collas, Philippe, Mann, Matthias, Hake, Sandra B

“…Histone chaperones prevent promiscuous histone interactions before chromatin assembly. They guarantee faithful deposition of canonical histones and…”
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Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure by García-Giménez, José Luis, Òlaso, Gloria, Hake, Sandra B, Bönisch, Clemens, Wiedemann, Sonja M, Markovic, Jelena, Dasí, Francisco, Gimeno, Amparo, Pérez-Quilis, Carme, Palacios, Oscar, Capdevila, Mercè, Viña, José, Pallardó, Federico V

“…Here we report that chromatin, the complex and dynamic eukaryotic DNA packaging structure, is able to sense cellular redox changes. Histone H3, the only…”
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Dexamethasone treatment alters insulin, leptin, and adiponectin levels in male mice as observed in DIO but does not lead to alterations of metabolic phenotypes in the offspring by Bönisch, Clemens, Irmler, Martin, Brachthäuser, Laura, Neff, Frauke, Bamberger, Mareike T., Marschall, Susan, Hrabě de Angelis, Martin, Beckers, Johannes

“…Epigenetic inheritance (EI) of metabolic phenotypes via the paternal lineage has been shown in rodent models of diet-induced obesity (DIO). However, the…”
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ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression by Ratnakumar, Kajan, Duarte, Luis F, LeRoy, Gary, Hasson, Dan, Smeets, Daniel, Vardabasso, Chiara, Bönisch, Clemens, Zeng, Tianying, Xiang, Bin, Zhang, David Y, Li, Haitao, Wang, Xiaowo, Hake, Sandra B, Schermelleh, Lothar, Garcia, Benjamin A, Bernstein, Emily

“…The histone variant macroH2A generally associates with transcriptionally inert chromatin; however, the factors that regulate its chromatin incorporation remain…”
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H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization by Bönisch, Clemens, Schneider, Katrin, Pünzeler, Sebastian, Wiedemann, Sonja M, Bielmeier, Christina, Bocola, Marco, Eberl, H Christian, Kuegel, Wolfgang, Neumann, Jürgen, Kremmer, Elisabeth, Leonhardt, Heinrich, Mann, Matthias, Michaelis, Jens, Schermelleh, Lothar, Hake, Sandra B

“…The histone variant H2A.Z has been implicated in many biological processes, such as gene regulation and genome stability. Here, we present the identification…”
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Chromatin proteomics and epigenetic regulatory circuits by Bönisch, Clemens, Nieratschker, Sonja M, Orfanos, Nikos K, Hake, Sandra B

“…Many phenotypic changes of eukaryotic cells due to changes in gene expression depend on alterations in chromatin structure. Processes involved in the…”
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Degradation of hsp70 and Other mRNAs in Drosophila via the 5′–3′ Pathway and Its Regulation by Heat Shock by Bönisch, Clemens, Temme, Claudia, Moritz, Bodo, Wahle, Elmar

“…Two general pathways of mRNA decay have been characterized in yeast. Both start with deadenylation. The major pathway then proceeds via cap hydrolysis and…”
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The histone methyltransferase Dot1 is required for DNA damage repair and proper development in Dictyostelium by Müller-Taubenberger, Annette, Bönisch, Clemens, Fürbringer, Marlis, Wittek, Finni, Hake, Sandra B.

“…► Dot1-dependent histone H3 K79 methylation is conserved in Dictyostelium discoideum. ► Dot1 is important for development and DNA damage repair processes in D…”
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Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines: e0134503 by Horsch, Marion, Aguilar-Pimentel, Juan Antonio, Bonisch, Clemens, Come, Christophe, Kolster-Fog, Cathrine, Jensen, Klaus T, Lund, Anders H, Lee, Icksoo, Grossman, Lawrence I, Sinkler, Christopher

“…We established a selection strategy to identify new models for an altered airway inflammatory response from a large compendium of mutant mouse lines that were…”
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