Search Results - "Böker, Kai Oliver"
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Current Methods for Skeletal Muscle Tissue Repair and Regeneration
Published in BioMed research international (01-01-2018)“…Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of muscle loss, this regeneration needs interventional support…”
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Extracellular Vesicles Allow Epigenetic Mechanotransduction between Chondrocytes and Osteoblasts
Published in International journal of molecular sciences (10-12-2021)“…MicroRNAs (miRNAs) can be transported in extracellular vesicles (EVs) and are qualified as possible messengers for cell-cell communication. In the context of…”
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The Interaction between microRNAs and the Wnt/β-Catenin Signaling Pathway in Osteoarthritis
Published in International journal of molecular sciences (13-09-2021)“…Osteoarthritis (OA) is a chronic disease affecting the whole joint, which still lacks a disease-modifying treatment. This suggests an incomplete understanding…”
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Reduced Cell Adhesion on LightPLAS-Coated Implant Surfaces in a Three-Dimensional Bioreactor System
Published in International journal of molecular sciences (18-07-2023)“…Most implants used in trauma surgery are made of steel and remain inside the body only temporarily. The strong tissue interaction of such implants sometimes…”
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Laser Ablated Periodic Nanostructures on Titanium and Steel Implants Influence Adhesion and Osteogenic Differentiation of Mesenchymal Stem Cells
Published in Materials (10-08-2020)“…Metal implants used in trauma surgeries are sometimes difficult to remove after the completion of the healing process due to the strong integration with the…”
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Osteogenic Effect of Pregabalin in Human Primary Mesenchymal Stem Cells, Osteoblasts, and Osteosarcoma Cells
Published in Life (Basel, Switzerland) (28-03-2022)“…Seventy million patients worldwide are suffering from epilepsy. The long-term use of antiepileptic drugs causes the alteration of the bone tissue and its…”
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Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9
Published in Molecular therapy. Methods & clinical development (15-06-2018)“…Research on cell-free vesicles revealed a multitude of characteristics, in particular of microvesicles and exosomes, that range from their potential as…”
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Biomechanical investigation of positive reduction in the femoral neck fracture: a finite element analysis
Published in Frontiers in bioengineering and biotechnology (09-10-2024)“…Gotfried positive reduction offers an alternative strategy for femoral neck fracture (FNF) when achieving anatomical reduction is challenging. However, the…”
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Identification and characterization of human xylosyltransferase II promoter single nucleotide variants
Published in Biochemical and biophysical research communications (20-03-2015)“…The human isoenzymes xylosyltransferase-I and -II (XT-I, XT-II) catalyze the rate-limiting step in proteoglycan biosynthesis. Therefore, serum XT activity,…”
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The HIFα-Stabilizing Drug Roxadustat Increases the Number of Renal Epo-Producing Sca-1 + Cells
Published in Cells (Basel, Switzerland) (21-02-2022)“…Inhibition of the prolyl-4-hydroxylase domain (PHD) enzymes, leading to the stabilization of hypoxia-inducible factor (HIF) α as well as to the stimulation of…”
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First description of the complete human xylosyltransferase-I promoter region
Published in BMC genetics (05-12-2014)“…Human xylosyltransferase-I (XT-I) catalyzes the rate-limiting step in proteoglycan glycosylation. An increase in XYLT1 mRNA expression and serum XT activity is…”
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