Search Results - "Böker, K. H."

Distinct roles of free leptin, bound leptin and soluble leptin receptor during the metabolic‐inflammatory response in patients with liver cirrhosis by OCKENGA, J., TIETGE, U. J. F., BÖKER, K. H. W., MANNS, M. P., BRABANT, G., BAHR, M. J.

“…Summary Background Alteration of the leptin system appears to play a role in the inflammatory–metabolic response in catabolic diseases such as chronic liver…”
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Real‐world use, effectiveness and safety of anti‐viral treatment in chronic hepatitis C genotype 3 infection by Cornberg, M., Petersen, J., Schober, A., Mauss, S., Böker, K. H. W., Link, R., Günther, R., Serfert, Y., Pfeiffer‐Vornkahl, H., Manns, M. P., Sarrazin, C., Hüppe, D., Berg, T., Niederau, C.

“…Summary Background Treatment of chronic hepatitis C genotype 3 (GT3) is more challenging compared with other genotypes. Since 2014, several new treatment…”
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Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation by Arkenau, H T, Stichtenoth, D O, Frölich, J C, Manns, M P, Böker, K H W

“…Chronic liver diseases are accompanied by changes in splanchnic and systemic circulation. These changes are characterised by a reduction in peripheral vascular…”
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Comparison of matrix metalloproteinase expression in normal and cirrhotic human liver by LICHTINGHAGEN, R, BREITENSTEIN, K, ARNDT, B, KÜHBACHER, T, BÖKER, K. H. W

“…To study the extend of ongoing tissue remodelling in end-stage cirrhosis, the expression of different matrix metalloproteinases [interstitial collagenase…”
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Hypermetabolism in clinically stable patients with liver cirrhosis by Muller, M.J, Bottcher, J, Selberg, O, Weselmann, S, Boker, K.H.W, Schwarze, M, Muhlen, A. von zur, Manns, M.P

“…Background: Hypermetabolism has a negative effect on prognosis in patients with liver cirrhosis. Its exact prevalence and associations with clinical data, the…”
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Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under hbig immunoglobulin after liver transplantation by Tillmann, Hans L., Trautwein, Christian, Bock, Thomas, Böker, Klaus H., Jäckel, Elmar, Glowienka, Medea, Oldhafer, Karl, Bruns, Insa, Gauthier, Josee, Condreay, Lynn D., Raab, Hans‐Rudolf, Manns, Michael P.

“…Famciclovir (FCV) and lamivudine (LAM) reduce viral replication in patients with recurrent hepatitis B virus (HBV) infection after orthotopic liver…”
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Differential distribution of five members of the matrix metalloproteinase family and one inhibitor (TIMP-1) in human liver and skin by Geisler, S, Lichtinghagen, R, Böker, K H, Veh, R W

“…Matrix metalloproteinases represent a family of zinc-dependent proteolytic enzymes thought to be involved in normal and disease-related tissue remodeling…”
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Improvement of acute and chronic renal dysfunction in liver transplant patients after substitution of calcineurin inhibitors by mycophenolate mofetil by BARKMANN, A, NASHAN, B, SCHLITT, H. J, SCHMIDT, H. H. J, BÖKER, K. H. W, EMMANOUILIDIS, N, ROSENAU, J, BAHR, M. J, HOFFMANN, M. W, MANNS, M. P, KLEMPNAUER, J

“…Renal dysfunction caused by treatment with the calcineurin inhibitors (CNI) is a major problem in the long-term course after liver transplantation. In 22 liver…”
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Improved outcome of chronic hepatitis B after heart transplantation by long-term antiviral therapy by Potthoff, A., Tillmann, H. L., Bara, C., Deterding, K., Pethig, K., Meyer, S., Haverich, A., Böker, K. H. W., Manns, M. P., Wedemeyer, H.

“…Chronic hepatitis B progresses to cirrhosis in the majority of immunosuppressed patients. The outcome of long‐term antiviral therapy in HBV‐infected organ…”
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Long‐term outcome of hepatitis C virus infection after liver transplantation by Böker, K. H., Dalley, G., Bahr, M. J., Maschek, H., Tillmann, H. L., Trautwein, C., Oldhaver, K., Bode, U., Pichlmayr, R., Manns, M. P.

“…We analyzed the long‐term clinical course of 71 patients with RNA‐positive hepatitis C virus (HCV) infection after liver transplantation. Patients with…”
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Hepatitis B virus mutations in the pre-S genome before and after liver transplantation by TRAUTWEIN, C, SCHREM, H, TILLMANN, H. L, KUBICKA, S, WALKER, D, BÖKER, K. H. W, MASCHEK, H.-J, PICHLMAYR, R, MANNS, M. P

“…Mutational changes in the pre-S region of hepatitis B virus (HBV) were analyzed in 20 patients who experienced HBV reinfection after orthotopic liver…”
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Prostaglandin E plus famciclovir--a new concept for the treatment of severe hepatitis B after liver transplantation by Böker, K H, Ringe, B, Krüger, M, Pichlmayr, R, Manns, M P

“…New concepts for the treatment of hepatitis B in immunocompromised patients are urgently needed. We describe our first experience with the new antiviral agent…”
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Tissue inhibitors of metalloproteinases in liver and serum/plasma in chronic active hepatitis C and HCV-induced cirrhosis by Böker, K H, Pehle, B, Steinmetz, C, Breitenstein, K, Bahr, M, Lichtinghagen, R

“…The development of liver cirrhosis can be described as a process of tissue remodeling, which involves increased matrix turnover. In order to determine whether…”
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Treatment of hepatitis B-related polyarteritis nodosa with famciclovir and interferon alfa-2b by Krüger, Martin, Böker, Klaus H.W., Zeidler, Henning, Manns, Michael P.

“…Background: The association between polyarteritis nodosa and viral hepatitis B infection is well established and still remains a therapeutic challenge…”
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Famciclovir treatment of chronic hepatitis B in heart transplant recipients : A prospective trial by WEDEMEYER, H, BÖKER, K. H. W, HAVERICH, A, MANNS, M. P, PETHIG, K, PETZOLD, D. R, FLEMMING, P, TILLMANN, H. L, VOLLMAR, J, BASTÜRK, M, GOLDMANN, E, GRIFFIN, K. E

“…Hepatitis B may take a rapid and aggressive course in patients under immunosuppression. Nucleoside analogues have been shown to suppress viral replication…”
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Hepatoma with severe non-islet cell tumor hypoglycemia by Tietge, Uwe J F, Schöfl, Christof, Ocran, Kenneth W, Wagner, Siegfried, Böker, Klaus H.W., Brabant, Georg, Zapf, Jürgen, Manns, Michael P

“…We report a 22-yr-old male patient with chronic hepatitis B and a large, well differentiated hepatoma who developed episodes of symptomatic fasting…”
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Persistence of Autoantibodies against Recombinant Mitochondrial and Nuclear Pore Proteins after Orthotopic Liver Transplantation for Primary Biliary Cirrhosis by Mattalia, Alberto, Lüttig, Birgit, Rosina, Floriano, Leung, Patrick S.C., Van de Water, Judy, Bauducci, Marzia, Ciancio, Alessia, Böker, Klaus H.W., Worman, Howard, Cooper, Ross L., Manns, Michael, Ansari, Aftab, Rizzetto, Mario, Gershwin, M.Eric

“…Primary biliary cirrhosis is an autoimmune disease characterized by high titer autoantibodies predominantly against mitochondrial antigens PDC-E2, BCOADC-E2…”
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Immunosuppression and the prognosis of patients suffering from myeloproliferative disorders after liver transplantation by Bahr, M.J, Rosenau, J, Tietge, U.J.F, Caselitz, M, Hofmann, M.W, Klempnauer, J, Böker, K.H.W, Strassburg, C.P, Manns, M.P

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Serum laminin P1 levels do not reflect critically elevated portal pressure in patients with liver cirrhosis by Bahr, M J, Böker, K H, Horn, W, Günzler, V, Manns, M P

“…Laminin P1 serum levels run parallel to the accumulation of hepatic extracellular matrix in patients with liver cirrhosis. Recent studies reported a…”
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Tacrolimus (FK 506) biotransformation in primary rat hepatocytes depends on extracellular matrix geometry by Bader, A, Knop, E, Böker, K H, Crome, O, Frühauf, N, Gonschior, A K, Christians, U, Esselmann, H, Pichlmayr, R, Sewing, K F

“…Established in vitro models for studies of hepatic drug biotransformation include the use of primary hepatocytes. In normal liver the space of Disse provides…”
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