Search Results - "Böhmer, Wesley"

Hydrogen‐Borrowing Alcohol Bioamination with Coimmobilized Dehydrogenases by Böhmer, Wesley, Knaus, Tanja, Mutti, Francesco G.

“…The amination of alcohols is an important transformation in chemistry. The redox‐neutral (i.e., hydrogen‐borrowing) asymmetric amination of alcohols is enabled…”
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Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω‐Transaminases by Böhmer, Wesley, Volkov, Alexey, Engelmark Cassimjee, Karim, Mutti, Francesco G.

“…Compared with biocatalysis in aqueous media, the use of enzymes in neat organic solvents enables increased solubility of hydrophobic substrates and can lead to…”
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Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines by Tseliou, Vasilis, Masman, Marcelo F., Böhmer, Wesley, Knaus, Tanja, Mutti, Francesco G.

“…Biocatalytic asymmetric amination of ketones, by using amine dehydrogenases (AmDHs) or transaminases, is an efficient method for the synthesis of α‐chiral…”
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Parallel Interconnected Kinetic Asymmetric Transformation (PIKAT) with an Immobilized ω-Transaminase in Neat Organic Solvent by Böhmer, Wesley, Koenekoop, Lucien, Simon, Timothée, Mutti, Francesco G

“…Comprising approximately 40% of the commercially available optically active drugs, α-chiral amines are pivotal for pharmaceutical manufacture. In this context,…”
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Highly efficient production of chiral amines in batch and continuous flow by immobilized ω-transaminases on controlled porosity glass metal-ion affinity carrier by Böhmer, Wesley, Knaus, Tanja, Volkov, Alexey, Slot, Thierry K., Shiju, N. Raveendran, Engelmark Cassimjee, Karim, Mutti, Francesco G.

“…•High retention of transaminase activity upon immobilization via Fe(III) affinity binding onto polymer-coated controlled porosity glass beads.•Optimization of…”
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Front Cover Picture: Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω‐Transaminases (Adv. Synth. Catal. 9/2020) by Böhmer, Wesley, Volkov, Alexey, Engelmark Cassimjee, Karim, Mutti, Francesco G.

“…The front cover picture, provided by Francesco Mutti's group and created by Verena Resch, illustrates the application of immobilized ω‐transaminases for the…”
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