Search Results - "Böhm, Sebastian W"

Functional Characterization of Glycoprotein H Chimeras Composed of Conserved Domains of the Pseudorabies Virus and Herpes Simplex Virus 1 Homologs by Böhm, Sebastian W, Backovic, Marija, Klupp, Barbara G, Rey, Felix A, Mettenleiter, Thomas C, Fuchs, Walter

“…Membrane fusion is indispensable for entry of enveloped viruses into host cells. The conserved core fusion machinery of the Herpesviridae consists of…”
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Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H by Böhm, Sebastian W, Eckroth, Elisa, Backovic, Marija, Klupp, Barbara G, Rey, Felix A, Mettenleiter, Thomas C, Fuchs, Walter

“…Enveloped viruses utilize membrane fusion for entry into, and release from, host cells. For entry, members of the Herpesviridae require at least three envelope…”
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A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A) by Böhm, Sebastian W, Backovic, Marija, Klupp, Barbara G, Rey, Felix A, Mettenleiter, Thomas C, Fuchs, Walter

“…Glycoprotein gH is essential for herpesvirus-induced membrane fusion during entry and cell-to-cell spread. Structural analyses of gH homologues revealed a…”
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