Search Results - "Böhm, Manfred"

Blood Pressure Reduction and Diabetes Insipidus in Transgenic Rats Deficient in Brain Angiotensinogen by Schinke, Martina, Baltatu, Ovidiu, Böhm, Manfred, Peters, Jörg, Rascher, Wolfgang, Bricca, Giampiero, Lippoldt, Andrea, Ganten, Detlev, Bader, Michael

“…Angiotensin produced systemically or locally in tissues such as the brain plays an important role in the regulation of blood pressure and in the development of…”
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Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN) by Monti, J, Schinke, M, Böhm, M, Ganten, D, Bader, M, Bricca, G

“…TGR(ASrAOGEN)680, a newly developed transgenic rat line with specific downregulation of astroglial synthesis of angiotensinogen, exhibits decreased brain…”
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Differential Gene Expression of Renin and Angiotensinogen in the TGR(mREN-2)27 Transgenic Rat by Lee, Min, Bohm, Manfred, Kim, Shokei, Bachmann, Sebastian, Bachmann, Jurgen, Bader, Michael, Ganten, Detlev

“…Transgenic rats carrying the murine Ren-2 gene represent a monogenetic model of hypertension characterized by low plasma renin and high extrarenal expression…”
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Permanent Inhibition of Angiotensinogen Synthesis by Antisense RNA Expression by Schinke, Martina, Bohm, Manfred, Bricca, Giampiero, Ganten, Detlev, Bader, Michael

“…The renin-angiotensin system plays a pivotal role in blood pressure regulation. Recent molecular biological findings led to the new concept that in addition to…”
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Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype by Lecce, Laura, Xu, Yang, V'Gangula, Bhargavi, Chandel, Nirupama, Pothula, Venu, Caudrillier, Axelle, Santini, Maria Paola, d'Escamard, Valentina, Ceholski, Delaine K, Gorski, Przemek A, Ma, Lijiang, Koplev, Simon, Bjørklund, Martin Mæng, Björkegren, Johan Lm, Boehm, Manfred, Bentzon, Jacob Fog, Fuster, Valentin, Kim, Ha Won, Weintraub, Neal L, Baker, Andrew H, Bernstein, Emily, Kovacic, Jason C

“…Endothelial-mesenchymal transition (EndMT) is associated with various cardiovascular diseases and in particular with atherosclerosis and plaque instability…”
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Circadian Blood Pressure Variation in Transgenic Hypertensive Rats by Lemmer, Björn, Mattes, Andreas, Böhm, Manfred, Ganten, Detlev

“…Automatic, around-the-clock blood pressure measurements have increased our understanding of hypertension in humans. Patients with essential hypertension…”
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Pilot study to evaluate the safety and effectiveness of etidronate treatment for arterial calcification due to deficiency of CD73 (ACDC) by Ferrante, Elisa A, Cudrici, Cornelia D, Rashidi, Mahmood, Fu, Yi-Ping, Huffstutler, Rebecca, Carney, Katherine, Chen, Marcus Y, St Hilaire, Cynthia, Smith, Kevin, Bagheri, Hadi, Katz, James D, Ferreira, Carlos R, Gahl, William A, Boehm, Manfred, Brofferio, Alessandra

“…Background: Arterial calcification due to deficiency of CD73 (ACDC; OMIM 211800) is a rare genetic disease resulting in calcium deposits in arteries and small…”
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Stem cell-derived motor neurons from spinal and bulbar muscular atrophy patients by Grunseich, Christopher, Zukosky, Kristen, Kats, Ilona R, Ghosh, Laboni, Harmison, George G, Bott, Laura C, Rinaldi, Carlo, Chen, Ke-lian, Chen, Guibin, Boehm, Manfred, Fischbeck, Kenneth H

“…Abstract Spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) is a motor neuron disease caused by polyglutamine repeat expansion in the androgen…”
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Tissue renin-angiotensin systems. Their role in cardiovascular disease by Lee, M A, Böhm, M, Paul, M, Ganten, D

“…The identification of the components of the renin-angiotensin system (RAS) in various extrarenal tissues suggested the existence of local renin-angiotensin…”
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Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27 by Lee, M A, Böhm, M, Paul, M, Bader, M, Ganten, U, Ganten, D

“…Transgenic techniques represent powerful tools for the study of gene-related mechanisms of diseases such as hypertension, which results from a complex…”
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Suboptimal hydration remodels metabolism, promotes degenerative diseases, and shortens life by Allen, Michele D., Springer, Danielle A., Burg, Maurice B., Boehm, Manfred, Dmitrieva, Natalia I.

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Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade by Böhm, M, Lippoldt, A, Wienen, W, Ganten, D, Bader, M

“…TGR(mREN2)27 is a transgenic rat harboring the murine Ren-2 gene and exhibit fulminant hypertension and marked heart hypertrophy. In order to study the role of…”
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Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions by Böhm, M, Lee, M, Kreutz, R, Kim, S, Schinke, M, Djavidani, B, Wagner, J, Kaling, M, Wienen, W, Bader, M

“…To study the effect of angiotensin II receptor AT1 blockade on blood pressure, gene expression and pathomorphology of transgenic rats harbouring the mouse…”
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Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats by BADER, M, YI ZHAO, SANDER, M, MIN AE LEE, BACHMANN, J, BÖHM, M, BEHRUS DJAVIDANI, PETERS, J, MULLINS, J. J, GANTEN, D

“…A transgenic rat line, TGR(mREN2)27, was established by introducing the murine Ren-2 gene into the genome of rats by microinjection techniques. These rats…”
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Effects of angiotensin-converting enzyme inhibitors on tissue renin-angiotensin systems by Lee, Min A.E., Paul, Martin, Böhm, Manfred, Ganten, Detlev

“…The renin-angiotensin system (RAS) plays a major role in the control of blood pressure and cardiovascular homeostasis and is involved in the pathogenesis of a…”
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Human blood vessel organoids as a model of diabetic vasculopathy by Wimmer, Reiner A., Leopoldi, Alexandra, Aichinger, Martin, Wick, Nikolaus, Hantusch, Brigitte, Novatchkova, Maria, Taubenschmid, Jasmin, Hämmerle, Monika, Esk, Christopher, Bagley, Joshua A., Lindenhofer, Dominik, Chen, Guibin, Boehm, Manfred, Agu, Chukwuma A., Yang, Fengtang, Fu, Beiyuan, Zuber, Johannes, Knoblich, Juergen A., Kerjaschki, Dontscho, Penninger, Josef M.

“…The increasing prevalence of diabetes has resulted in a global epidemic 1 . Diabetes is a major cause of blindness, kidney failure, heart attacks, stroke and…”
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Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals by Bricca, Giampiero, Schinke, Martina, Böhm, Manfred, Monti, Jan, Hof, Holger, Ganten, Detlev, Bader, Michael

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Concepts for a model of good medical laboratory services by Haeckel, R, Böhm, M, Capel, P J, Høiby, N, Jansen, R T, Kallner, A, Kelly, A, Kruse-Jarres, J D, Küffer, H, Libeer, J C

“…Several international standards and corresponding interpretation documents for quality management systems have been published. Although these standards are…”
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Bone marrow–derived immune cells regulate vascular disease through a p27Kip1-dependent mechanism by Boehm, Manfred, Olive, Michelle, True, Andrea L., Crook, Martin F., San, Hong, Qu, Xuan, Nabel, Elizabeth G.

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Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression by Lubick, Kirk J., Robertson, Shelly J., McNally, Kristin L., Freedman, Brett A., Rasmussen, Angela L., Taylor, R. Travis, Walts, Avram D., Tsuruda, Seitaro, Sakai, Mizuki, Ishizuka, Mariko, Boer, Elena F., Foster, Erin C., Chiramel, Abhilash I., Addison, Conrad B., Green, Richard, Kastner, Daniel L., Katze, Michael G., Holland, Steven M., Forlino, Antonella, Freeman, Alexandra F., Boehm, Manfred, Yoshii, Kentaro, Best, Sonja M.

“…Type I interferon (IFN-α/β or IFN-I) signals through two receptor subunits, IFNAR1 and IFNAR2, to orchestrate sterile and infectious immunity. Cellular…”
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