Search Results - "Böhlen, T."

Dosimetric verification in water of a Monte Carlo treatment planning tool for proton, helium, carbon and oxygen ion beams at the Heidelberg Ion Beam Therapy Center by Tessonnier, T, Böhlen, T T, Ceruti, F, Ferrari, A, Sala, P, Brons, S, Haberer, T, Debus, J, Parodi, K, Mairani, A

“…The introduction of 'new' ion species in particle therapy needs to be supported by a thorough assessment of their dosimetric properties and by treatment…”
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The FLUKA Code: Developments and Challenges for High Energy and Medical Applications by Böhlen, T.T., Cerutti, F., Chin, M.P.W., Fassò, A., Ferrari, A., Ortega, P.G., Mairani, A., Sala, P.R., Smirnov, G., Vlachoudis, V.

“…The FLUKA Monte Carlo code is used extensively at CERN for all beam-machine interactions, radioprotection calculations and facility design of forthcoming…”
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Distributions of secondary particles in proton and carbon-ion therapy: a comparison between GATE/Geant4 and FLUKA Monte Carlo codes by Robert, C, Dedes, G, Battistoni, G, Böhlen, T T, Buvat, I, Cerutti, F, Chin, M P W, Ferrari, A, Gueth, P, Kurz, C, Lestand, L, Mairani, A, Montarou, G, Nicolini, R, Ortega, P G, Parodi, K, Prezado, Y, Sala, P R, Sarrut, D, Testa, E

“…Monte Carlo simulations play a crucial role for in-vivo treatment monitoring based on PET and prompt gamma imaging in proton and carbon-ion therapies. The…”
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A joint physics and radiobiology DREAM team vision – Towards better response prediction models to advance radiotherapy by Vens, C., van Luijk, P., Vogelius, R.I., El Naqa, I., Humbert-Vidan, L., von Neubeck, C., Gomez-Roman, N., Bahn, E., Brualla, L., Böhlen, T.T., Ecker, S., Koch, R., Handeland, A., Pereira, S., Possenti, L., Rancati, T., Todor, D., Vanderstraeten, B., Van Heerden, M., Ullrich, W., Jackson, M., Alber, M., Marignol, L.

“…•Optimal RT outcomes requires accurate robust predictive radiation oncology models.•Present challenges in model and data quality must be addressed to improve…”
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Investigating the robustness of ion beam therapy treatment plans to uncertainties in biological treatment parameters by Böhlen, T T, Brons, S, Dosanjh, M, Ferrari, A, Fossati, P, Haberer, T, Patera, V, Mairani, A

“…Uncertainties in determining clinically used relative biological effectiveness (RBE) values for ion beam therapy carry the risk of absolute and relative…”
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Commissioning of pencil beam and Monte Carlo dose engines for non-isocentric treatments in scanned proton beam therapy by Carlino, A, Böhlen, T, Vatnitsky, S, Grevillot, L, Osorio, J, Dreindl, R, Palmans, H, Stock, M, Kragl, G

“…This work describes the dosimetric commissioning of the treatment planning system (TPS) RayStation v6.1 from RaySearch Laboratories (Stockholm, Sweden) for a…”
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Data-driven RBE parameterization for helium ion beams by Mairani, A, Magro, G, Dokic, I, Valle, S M, Tessonnier, T, Galm, R, Ciocca, M, Parodi, K, Ferrari, A, Jäkel, O, Haberer, T, Pedroni, P, Böhlen, T T

“…Helium ion beams are expected to be available again in the near future for clinical use. A suitable formalism to obtain relative biological effectiveness (RBE)…”
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Development of the Flair tool for FLUKA Treatment Planning Verification by Kozłowska, W, Böhlen, T, Ferrari, A, Georg, D, Mairani, A, Sala, P, Vlachoudis, V

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The FIRST experiment at GSI by Pleskac, R., Abou-Haidar, Z., Agodi, C., Alvarez, M.A.G., Aumann, T., Battistoni, G., Bocci, A., Böhlen, T.T., Boudard, A., Brunetti, A., Carpinelli, M., Cirrone, G.A.P., Cortes-Giraldo, M.A., Cuttone, G., De Napoli, M., Durante, M., Fernández-García, J.P., Finck, C., Golosio, B., Gallardo, M.I., Iarocci, E., Iazzi, F., Ickert, G., Introzzi, R., Juliani, D., Krimmer, J., Kurz, N., Labalme, M., Leifels, Y., Le Fevre, A., Leray, S., Marchetto, F., Monaco, V., Morone, M.C., Oliva, P., Paoloni, A., Piersanti, L., Quesada, J.M., Raciti, G., Randazzo, N., Romano, F., Rossi, D., Rousseau, M., Sacchi, R., Sala, P., Sarti, A., Scheidenberger, C., Schuy, C., Sciubba, A., Sfienti, C., Simon, H., Sipala, V., Spiriti, E., Stuttge, L., Tropea, S., Younis, H., Patera, V.

“…The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at the SIS accelerator of GSI laboratory in Darmstadt has been designed for the…”
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Performance of the reconstruction algorithms of the FIRST experiment pixel sensors vertex detector by Rescigno, R., Finck, Ch, Juliani, D., Spiriti, E., Baudot, J., Abou-Haidar, Z., Agodi, C., Alvarez, M.A.G., Aumann, T., Battistoni, G., Bocci, A., Böhlen, T.T., Boudard, A., Brunetti, A., Carpinelli, M., Cirrone, G.A.P., Cortes-Giraldo, M.A., Cuttone, G., De Napoli, M., Durante, M., Gallardo, M.I., Golosio, B., Iarocci, E., Iazzi, F., Ickert, G., Introzzi, R., Krimmer, J., Kurz, N., Labalme, M., Leifels, Y., Le Fevre, A., Leray, S., Marchetto, F., Monaco, V., Morone, M.C., Oliva, P., Paoloni, A., Patera, V., Piersanti, L., Pleskac, R., Quesada, J.M., Randazzo, N., Romano, F., Rossi, D., Rousseau, M., Sacchi, R., Sala, P., Sarti, A., Scheidenberger, C., Schuy, C., Sciubba, A., Sfienti, C., Simon, H., Sipala, V., Tropea, S., Vanstalle, M., Younis, H.

“…Hadrontherapy treatments use charged particles (e.g. protons and carbon ions) to treat tumors. During a therapeutic treatment with carbon ions, the beam…”
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A Monte Carlo-based treatment planning tool for proton therapy by Mairani, A, Böhlen, T T, Schiavi, A, Tessonnier, T, Molinelli, S, Brons, S, Battistoni, G, Parodi, K, Patera, V

“…In the field of radiotherapy, Monte Carlo (MC) particle transport calculations are recognized for their superior accuracy in predicting dose and fluence…”
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In response to the comments to the paper 'Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation' by T. Friedrich et al by Mairani, A., Böhlen, T. T., Dokic, I., Cabal, G., Brons, S., Haberer, T.

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On the influence of model parametrization in elastic full waveform tomography by Köhn, D., De Nil, D., Kurzmann, A., Przebindowska, A., Bohlen, T.

“…SUMMARY Elastic Full Waveform Tomography (FWT) aims to reduce the misfit between recorded and modelled data, to deduce a very detailed model of elastic…”
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Benchmarking nuclear models of FLUKA and GEANT4 for carbon ion therapy by Böhlen, T T, Cerutti, F, Dosanjh, M, Ferrari, A, Gudowska, I, Mairani, A, Quesada, J M

“…As carbon ions, at therapeutic energies, penetrate tissue, they undergo inelastic nuclear reactions and give rise to significant yields of secondary fragment…”
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FLUKA and PENELOPE simulations of 10keV to 10MeV photons in LYSO and soft tissue by Chin, M.P.W., Böhlen, T.T., Fassò, A., Ferrari, A., Ortega, P.G., Sala, P.R.

“…Monte Carlo simulations of electromagnetic particle interactions and transport by FLUKA and PENELOPE were compared. 10keV to 10MeV incident photon beams…”
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FLUKA particle therapy tool for Monte Carlo independent calculation of scanned proton and carbon ion beam therapy by Kozłowska, Wioletta S, Böhlen, Till T, Cuccagna, Caterina, Ferrari, Alfredo, Fracchiolla, Francesco, Magro, Giuseppe, Mairani, Andrea, Schwarz, Marco, Vlachoudis, Vasilis, Georg, Dietmar

“…While Monte Carlo (MC) codes are considered as the gold standard for dosimetric calculations, the availability of user friendly MC codes suited for particle…”
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Lateral response heterogeneity of Bragg peak ionization chambers for narrow-beam photon and proton dosimetry by Kuess, Peter, Böhlen, Till T, Lechner, Wolfgang, Elia, Alessio, Georg, Dietmar, Palmans, Hugo

“…Large area ionization chambers (LAICs) can be used to measure output factors of narrow beams. Dose area product measurements are proposed as an alternative to…”
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A phenomenological relative biological effectiveness approach for proton therapy based on an improved description of the mixed radiation field by Mairani, A, Dokic, I, Magro, G, Tessonnier, T, Bauer, J, Böhlen, T T, Ciocca, M, Ferrari, A, Sala, P R, Jäkel, O, Debus, J, Haberer, T, Abdollahi, A, Parodi, K

“…Proton therapy treatment planning systems (TPSs) are based on the assumption of a constant relative biological effectiveness (RBE) of 1.1 without taking into…”
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Dose- and Volume-Limiting Late Toxicity of FLASH Radiotherapy in Cats with Squamous Cell Carcinoma of the Nasal Planum and in Mini Pigs by Rohrer Bley, Carla, Wolf, Friederike, Gonçalves Jorge, Patrik, Grilj, Veljko, Petridis, Ioannis, Petit, Benoit, Böhlen, Till T, Moeckli, Raphael, Limoli, Charles, Bourhis, Jean, Meier, Valeria, Vozenin, Marie-Catherine

“…The FLASH effect is characterized by normal tissue sparing without compromising tumor control. Although demonstrated in various preclinical models, safe…”
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Model‐based control of mechanical ventilation: design and clinical validation by Martinoni, E.P., Pfister, Ch. A., Stadler, K.S., Schumacher, P.M., Leibundgut, D., Bouillon, T., Böhlen, T., Zbinden, A.M.

“…We developed a model‐based control system using end‐tidal carbon dioxide fraction (FE′CO2) to adjust a ventilator during clinical anaesthesia. We studied 16…”
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