Search Results - "Bégueret, Hugues"

Three-dimensional culture model to distinguish normal from malignant human bronchial epithelial cells by FESSART, Delphine, BEGUERET, Hugues, DELOM, Frederic

“…In the present study, we have developed an in vitro three-dimensional model to differentiate normal lung cells from lung cancer cells in order to study the…”
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SOX10, GATA3, GCDFP15, Androgen Receptor, and Mammaglobin for the Differential Diagnosis Between Triple-negative Breast Cancer and TTF1-negative Lung Adenocarcinoma by Laurent, Elodie, Begueret, Hugues, Bonhomme, Benjamin, Veillon, Rémi, Thumerel, Matthieu, Velasco, Valérie, Brouste, Véronique, Hoppe, Stéphanie, Fournier, Marion, Grellety, Thomas, MacGrogan, Gaëtan

“…Triple-negative breast cancer (TNBC) patients have an increased risk of developing visceral metastases and other primary nonbreast cancers, particularly lung…”
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Neuroendocrine phenotype as an acquired resistance mechanism in ALK-rearranged lung adenocarcinoma by Caumont, Charline, Veillon, Rémi, Gros, Audrey, Laharanne, Elodie, Bégueret, Hugues, Merlio, Jean-Philippe

“…Highlights • We report a case of acquired neuroendocrine phenotype after crizotinib therapy. • ALK -rearrangement was associated with resistance to crizotinib…”
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Secretion of protein disulphide isomerase AGR2 confers tumorigenic properties by Fessart, Delphine, Domblides, Charlotte, Avril, Tony, Eriksson, Leif A, Begueret, Hugues, Pineau, Raphael, Malrieux, Camille, Dugot-Senant, Nathalie, Lucchesi, Carlo, Chevet, Eric, Delom, Frederic

“…The extracellular matrix (ECM) plays an instrumental role in determining the spatial orientation of epithelial polarity and the formation of lumens in…”
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Targeting the mitochondrial trifunctional protein restrains tumor growth in oxidative lung carcinomas by Amoedo, Nivea Dias, Sarlak, Saharnaz, Obre, Emilie, Esteves, Pauline, Bégueret, Hugues, Kieffer, Yann, Rousseau, Benoît, Dupis, Alexis, Izotte, Julien, Bellance, Nadège, Dard, Laetitia, Redonnet-Vernhet, Isabelle, Punzi, Giuseppe, Rodrigues, Mariana Figueiredo, Dumon, Elodie, Mafhouf, Walid, Guyonnet-Dupérat, Véronique, Gales, Lara, Palama, Tony, Bellvert, Floriant, Dugot-Senan, Nathalie, Claverol, Stéphane, Baste, Jean-Marc, Lacombe, Didier, Rezvani, Hamid Reza, Pierri, Ciro Leonardo, Mechta-Grigoriou, Fatima, Thumerel, Matthieu, Rossignol, Rodrigue

“…Metabolic reprogramming is a common hallmark of cancer, but a large variability in tumor bioenergetics exists between patients. Using high-resolution…”
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Parallel FISH and immunohistochemical studies of ALK status in 3244 non-small-cell lung cancers reveal major discordances by Cabillic, Florian, Gros, Audrey, Dugay, Frédéric, Begueret, Hugues, Mesturoux, Laura, Chiforeanu, Dan Cristian, Dufrenot, Leila, Jauffret, Vincent, Dachary, Dominique, Corre, Romain, Lespagnol, Alexandra, Soler, Gwendoline, Dagher, Julien, Catros, Véronique, Le Calve, Michèle, Merlio, Jean-Philippe, Belaud-Rotureau, Marc-Antoine

“…Anaplastic lymphoma kinase (ALK) rearrangements occur in 1% to 7% of non-small-cell lung cancers (NSCLCs). Crizotinib, an ALK inhibitor, has been demonstrated…”
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Lung histopathology of non‐infectious pulmonary complications after allogeneic haematopoietic stem cell transplantation by Meignin, Veronique, Thivolet‐Bejui, Francoise, Kambouchner, Marianne, Hussenet, Claire, Bondeelle, Louise, Mitchell, Andrew, Chagnon, Karine, Begueret, Hugues, Segers, Valerie, Cottin, Vincent, Tazi, Abdellatif, Chevret, Sylvie, Danel, Claire, Bergeron, Anne

“…Aims Non‐infectious pulmonary complications (NIPCs) occur frequently following allogeneic haematopoietic stem cell transplantation (HSCT). As there is no…”
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Short-range interactions between fibrocytes and CD8 + T cells in COPD bronchial inflammatory response by Eyraud, Edmée, Maurat, Elise, Sac-Epée, Jean-Marc, Henrot, Pauline, Zysman, Maeva, Esteves, Pauline, Trian, Thomas, Dupuy, Jean-William, Leipold, Alexander, Saliba, Antoine-Emmanuel, Begueret, Hugues, Girodet, Pierre-Olivier, Thumerel, Matthieu, Hustache-Castaing, Romain, Marthan, Roger, Levet, Florian, Vallois, Pierre, Contin-Bordes, Cécile, Berger, Patrick, Dupin, Isabelle

“…Bronchi of chronic obstructive pulmonary disease (COPD) are the site of extensive cell infiltration, allowing persistent contact between resident cells and…”
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Circulating fibrocytes as a new tool to predict lung cancer progression after surgery? by Henrot, Pauline, Beaufils, Fabien, Thumerel, Matthieu, Eyraud, Edmée, Boudoussier, Augustin, Begueret, Hugues, Maurat, Elise, Girodet, Pierre-Olivier, Marthan, Roger, Berger, Patrick, Dupin, Isabelle, Zysman, Maéva

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Solid papillary mesothelial tumor by Churg, Andrew, Le Stang, Nolwenn, Dacic, Sanja, Pissaloux, Daniel, Begueret, Hugues, Dartigues, Peggy, Giusiano-Courcambeck, Sophie, Sequeiros, Ruth, Pairon, Jean-Claude, Tirode, Franck, Galateau-Sallé, Francoise

“…We report nine examples of a previously undescribed type of peritoneal circumscribed nodular mesothelial tumor characterized by nests or sheets of mesothelial…”
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Deciphering Unexpected Vascular Locations of Scedosporium spp. and Lomentospora prolificans Fungal Infections, France by Vignals, Carole, Emmerich, Joseph, Begueret, Hugues, Garcia-Hermoso, Dea, Martin-Blondel, Guillaume, Angoulvant, Adela, Blez, Damien, Bruneval, Patrick, Cassaing, Sophie, Catherinot, Emilie, Cahen, Pierre, Moluçon-Chabrot, Cécile, Chevenet, Carole, Delhaes, Laurence, Escaut, Lélia, Faruch, Marie, Grenouillet, Frédéric, Larosa, Fabrice, Limousin, Lucie, Longchampt, Elisabeth, Mellot, François, Nourrisson, Céline, Bougnoux, Marie-Elisabeth, Lortholary, Olivier, Roux, Antoine, Rozenblum, Laura, Puges, Mathilde, Lanternier, Fanny, Bronnimann, Didier

“…Scedosporium spp. and Lomentospora prolificans are emerging non-Aspergillus filamentous fungi. The Scedosporiosis/lomentosporiosis Observational Study we…”
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Role of YKL-40 in Bronchial Smooth Muscle Remodeling in Asthma by BARA, Imane, OZIER, Annaig, WOODS, Joanne, DE LARA, Jose-Manuel Tunon, MARTHAN, Roger, BERGER, Patrick, GIRODET, Pierre-Olivier, CARVALHO, Gabrielle, CATTIAUX, Jennifer, BEGUERET, Hugues, THUMEREL, Matthieu, OUSOVA, Olga, KOLBECK, Roland, COYLE, Anthony J

“…Bronchial remodeling, including increased bronchial smooth muscle (BSM) mass, contributes to bronchial obstruction in asthma. However, its mechanisms are…”
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Lung intragraft donor-specific antibodies as a risk factor for graft loss by Visentin, Jonathan, Chartier, Albane, Massara, Layal, Linares, Gabriel, Guidicelli, Gwendaline, Blanchard, Elodie, Parrens, Marie, Begueret, Hugues, Dromer, Claire, Taupin, Jean-Luc

“…Background In lung transplantation, the impact of donor-specific anti-HLA antibodies (DSA) on graft survival is recognized, but not all serum DSA appear to be…”
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Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma by Trian, Thomas, Benard, Giovanni, Begueret, Hugues, Rossignol, Rodrigue, Girodet, Pierre-Olivier, Ghosh, Debajyoti, Ousova, Olga, Vernejoux, Jean-Marc, Marthan, Roger, Tunon-de-Lara, José-Manuel, Berger, Patrick

“…Asthma and chronic obstructive pulmonary disease (COPD) are characterized by different patterns of airway remodeling, which all include an increased mass of…”
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French multicentric validation of ALK rearrangement diagnostic in 547 lung adenocarcinomas by Lantuejoul, Sylvie, Rouquette, Isabelle, Blons, Hélène, Le Stang, Nolwenn, Ilie, Marius, Begueret, Hugues, Grégoire, Valerie, Hofman, Paul, Gros, Audrey, Garcia, Stephane, Monhoven, Nathalie, Devouassoux-Shisheboran, Mojgan, Mansuet-Lupo, Audrey, Thivolet, Françoise, Antoine, Martine, Vignaud, Jean-Michel, Penault-Llorca, Frederique, Galateau-Sallé, Françoise, McLeer-Florin, Anne

“…Anaplastic lymphoma kinase (ALK) gene rearrangements in lung adenocarcinoma result in kinase activity targetable by crizotinib. Although fluorescence in situ…”
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NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity by Cardouat, Guillaume, Douard, Matthieu, Bouchet, Clément, Roubenne, Lukas, Kmecová, Zuzana, Esteves, Pauline, Brette, Fabien, Guignabert, Christophe, Tu, Ly, Campagnac, Marilyne, Robillard, Paul, Coste, Florence, Delcambre, Frédéric, Thumerel, Matthieu, Begueret, Hugues, Maurac, Arnaud, Belaroussi, Yaniss, Klimas, Jan, Ducret, Thomas, Quignard, Jean-François, Vacher, Pierre, Baudrimont, Isabelle, Marthan, Roger, Berger, Patrick, Guibert, Christelle, Freund-Michel, Véronique

“…Pulmonary hypertension (PH) is characterised by an increase in pulmonary arterial pressure, ultimately leading to right ventricular failure and death. We have…”
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Primary lung low-grade fibromyxoid sarcoma: A rare case with A diagnostic dilemma by Ayadi, Aida, Houcine, Yoldez, Moussa, Chirine, Rouis, Houda, Abid, Tarek, Hugues, Begueret, Le Loarer, François

“…Low-grade fibromyxoid sarcoma (LGFMS) is a rare, low-grade malignant soft tissue tumor that is often mistaken for benign or more rarely malignant tumor types…”
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Pulmonary hyalinizing granuloma: a multicenter study of 5 new cases and review of the 135 cases of the literature by Lhote, Raphael, Haroche, Julien, Duron, Loïc, Girard, Nicolas, Lafourcade, Marie Pierre, Martin, Michel, Begueret, Hugues, Taytard, André, Capron, Frédérique, Grenier, Philippe, Piette, Jean Charles, Cohen-Aubart, Fleur, Amoura, Zahir

“…Pulmonary hyalinizing granuloma (PHG) is a rare disease characterized by single or multiple benign lung nodules mimicking lung neoplasma. Histologic analysis…”
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Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients by Trian, Thomas, PhD, Allard, Benoit, PhD, Ozier, Annaig, MD, PhD, Maurat, Elise, Dupin, Isabelle, PhD, Thumerel, Matthieu, MD, Ousova, Olga, PhD, Gillibert-Duplantier, Jennifer, PhD, Le Morvan, Valérie, PhD, Begueret, Hugues, MD, PhD, Girodet, Pierre-Olivier, MD, PhD, Marthan, Roger, MD, PhD, Berger, Patrick, MD, PhD

“…Background Increase of bronchial smooth muscle (BSM) mass is a crucial feature of asthma remodeling. The mechanisms of such an increased BSM mass are complex…”
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Pathology of the mediastinum. Case 5. Well-differentiated neuroendocrine carcinoma. Atypical carcinoid by Bégueret, Hugues

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