Search Results - "Bès, Cédric"

Physicochemical and Biological Characterization of RTXM83, a New Rituximab Biosimilar by Cerutti, María L., Pesce, Analía, Bès, Cédric, Seigelchifer, Mauricio

“…Background RTXM83 is a rituximab biosimilar with proven clinical safety and efficacy. It is the first rituximab biosimilar developed and approved in South…”
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Localization of the Discontinuous Immunodominant Region Recognized by Human Anti-thyroperoxidase Autoantibodies in Autoimmune Thyroid Diseases by Bresson, Damien, Cerutti, Martine, Devauchelle, Gérard, Pugnière, Martine, Roquet, Francoise, Bes, Cédric, Bossard, Carine, Chardès, Thierry, Péraldi-Roux, Sylvie

“…The discontinuous immunodominant region (IDR) recognized by autoantibodies directed against the thyroperoxidase (TPO) molecule, a major autoantigen in…”
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Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG1 antibody with specificity for the CDR3-like loop on the D1 domain of the CD4 molecule by TROADEC, Samuel, BES, Cédric, CHARDES, Thierry, CHENTOUF, Myriam, NGUYEN, Brigitte, BRIANT, Laurence, JACQUET, Chantal, CHEBLI, Karim, PUGNIERE, Martine, ROQUET, Francoise, CERUTTI, Martine

“…A baculovirus-expressed chimeric recombinant IgG1 (rIgG1) antibody, with Cgamma1 and Ckappa human constant domains, was derived from the murine monoclonal…”
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Recombinant Anti-CD4 Antibody 13B8.2 Blocks Membrane-Proximal Events by Excluding the Zap70 Molecule and Downstream Targets SLP-76, PLCγ1, and Vav-1 from the CD4-Segregated Brij 98 Detergent-Resistant Raft Domains by Chentouf, Myriam, Ghannam, Soufiane, Bès, Cédric, Troadec, Samuel, Cérutti, Martine, Chardès, Thierry

“…The biological effects of rIgG1 13B8.2, directed against the CDR3-like loop on the D1 domain of CD4, are partly due to signals that prevent NF-κB nuclear…”
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The human anti-thyroid peroxidase autoantibody repertoire in Graves' and Hashimoto's autoimmune thyroid diseases by Chardès, Thierry, Chapal, Nicolas, Bresson, Damien, Bès, Cédric, Giudicelli, Véronique, Lefranc, Marie-Paule, Péraldi-Roux, Sylvie

“…Human anti-thyroid peroxidase (TPO) autoantibodies (aAb) are generated during autoimmune thyroid diseases (AITD). Within recent years, increasing knowledge of…”
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Application of the Spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding by Laune, Daniel, Molina, Franck, Ferrières, Gaëlle, Villard, Sylvie, Bès, Cédric, Rieunier, François, Chardès, Thierry, Granier, Claude

“…Overlapping peptide scans prepared by Spot synthesis have been used to map interaction sites in several systems. Here we report our experience with this…”
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Biological actvities on T lymphoycytes of a baculovirus-expressed IgG1 antibody with specificities for the CDR3-like region of the CD4 molecule by Troadec, Samuel, Bès, Cédric, Chentouf, Myriam, Nguyen, Brigitte, Jacquet, Chantal, Chebli, Karim, Pugnière, Martine, Roquet, Françoise, Cerutti, Martine, Chardès, Thierry

“…A baculovirus-expressed chimeric recombinant IgG1 (rIgG1) antibody, with Cgamma1 and Ckappa human constant domains, was derived from the murine monoclonal…”
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PIN-bodies: A new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase by Bès, Cédric, Troadec, Samuel, Chentouf, Myriam, Breton, Hélène, Dominique Lajoix, Anne, Heitz, Frédéric, Gross, René, Plückthun, Andreas, Chardès, Thierry

“…By inserting the CB1 paratope-derived peptide (PDP) from the anti-CD4 13B8.2 antibody binding pocket into each of the three exposed loops of the protein…”
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Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains by Chentouf, Myriam, Ghannam, Soufiane, Bès, Cédric, Troadec, Samuel, Cérutti, Martine, Chardès, Thierry

“…The biological effects of rIgG(1) 13B8.2, directed against the CDR3-like loop on the D1 domain of CD4, are partly due to signals that prevent NF-kappaB nuclear…”
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Biological activities on T lymphocytes of a baculovirus-expressed chimeric recombinant IgG 1 antibody with specificity for the CDR3- like loop on the D1 domain of the CD4 molecule by Troadec, Samuel, Bès, Cédric, Chentouf, Myriam, Nguyen, Brigitte, Briant, Laurence, Jacquet, Chantal, Chebli, Karim, Pugnière, Martine, Roquet, Françoise, Cerutti, Martine, Chardès, Thierry

“…A baculovirus-expressed chimeric recombinant IgG 1 (rIgG 1) antibody, with Cγ 1 and Cκ human constant domains, was derived from the murine monoclonal antibody…”
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Localization of the discontinous immunodominant region recognized by human anti-thyroperoxidase autoantibodies in autoimmune thyroid diseases by Bresson, Damien, Cerutti, Martine, Devauchelle, Gerard, Pugnière, Martine, Roquet, Françoise, Bès, Cédric, Bossard, Carine, Chardès, Thierry, Péraldi-Roux, Sylvie

“…The discontinuous immunodominant region (IDR) recognized by autoantibodies directed against the thyroperoxidase (TPO) molecule, a major autoantigen in…”
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Mapping the Paratope of Anti-CD4 Recombinant Fab 13B8.2 by Combining Parallel Peptide Synthesis and Site-directed Mutagenesis by Bès, Cédric, Briant-Longuet, Laurence, Cerutti, Martine, Heitz, Frédéric, Troadec, Samuel, Pugnière, Martine, Roquet, Françoise, Molina, Franck, Casset, Florence, Bresson, Damien, Péraldi-Roux, Sylvie, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…We analyzed antigen-binding residues from the variable domains of anti-CD4 antibody 13B8.2 using the Spot method of parallel peptide synthesis. Sixteen amino…”
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Synthetic Peptides Derived from the Variable Regions of an Anti-CD4 Monoclonal Antibody Bind to CD4 and Inhibit HIV-1 Promoter Activation in Virus-infected Cells by Monnet, Céline, Laune, Daniel, Laroche-Traineau, Jeanny, Biard-Piechaczyk, Martine, Briant, Laurence, Bès, Cédric, Pugnière, Martine, Mani, Jean-Claude, Pau, Bernard, Cerutti, Martine, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…The monoclonal antibody (mAb) ST40, specific for the immunoglobulin complementarity-determining region (CDR) 3-like loop in domain 1 of the CD4 molecule,…”
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Corrigendum to: Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1 (FEBS 25428) : [ FEBS Letters 508 (2001) 67–74] by Bès, Cédric, Briant-Longuet, Laurence, Cerruti, Martine, De Berardinis, Piergiuseppe, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

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Corrigendum to: Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR‐H1‐derived peptide CB1 (FEBS 25428): FEBS Letters 508 (2001) 67–74 by Bès, Cédric, Briant-Longuet, Laurence, Cerruti, Martine, De Berardinis, Piergiuseppe, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

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Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR‐H1‐derived peptide CB1 1 by Bès, Cédric, Briant-Longuet, Laurence, Cerruti, Martine, DeBerardinis, Piergiuseppe, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…A systematic exploration of the V H 2/V κ 12–13 variable domains of the anti‐CD4 monoclonal antibody (mAb) 13B8.2 was performed by the Spot method to screen…”
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Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR‐H1‐derived peptide CB11 by Bès, Cédric, Briant-Longuet, Laurence, Cerruti, Martine, DeBerardinis, Piergiuseppe, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…A systematic exploration of the VH2/Vκ12–13 variable domains of the anti‐CD4 monoclonal antibody (mAb) 13B8.2 was performed by the Spot method to screen for…”
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The human anti-thyroid peroxidase autoantibody repertoire in Graves'and Hashimoto's autoimmune thyroid disease by Chardès, Thierry, Chapal, Nicolas, Bresson, Damien, Bès, Cédric, Giudicelli, Véronique, Lefranc, Marie-Paule, Peraldi-Roux, Sylvie

“…Human anti-thyroid peroxidase (TPO) autoantibodies (aAb) are generated during autoimmune thyroid diseases (AITD). Within recent years, increasing knowledge of…”
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Efficient CD4 binding and immunosuppressive properties of the 13B8.2 monoclonal antibody are displayed by its CDR-H1-derived peptide CB1 by Bès, Cédric, Briant-Longuet, Laurence, Cerruti, Martine, DeBerardinis, Piergiuseppe, Devauchelle, Gérard, Devaux, Christian, Granier, Claude, Chardès, Thierry

“…A systematic exploration of the V H2/V κ12–13 variable domains of the anti-CD4 monoclonal antibody (mAb) 13B8.2 was performed by the Spot method to screen for…”
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The chimeric mouse-human anti-CD4 Fab 13B8.2 expressed in baculovirus inhibits both antigen presentation and HIV-1 promoter activation by Bès, C, Cerutti, M, Briant-Longuet, L, Bresson, D, Peraldi-Roux, S, Pugnière, M, Mani, J C, Pau, B, Devaux, C, Granier, C, Devauchelle, G, Chardès, T

“…The anti-CD4 mAb 13B8.2, directed against the CDR3-like loop of the D1 domain of CD4, inhibits signal transduction pathways leading to both T cell activation…”
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