Search Results - "Bäuerlein, Felix J. B."

In situ architecture of neuronal α-Synuclein inclusions by Trinkaus, Victoria A., Riera-Tur, Irene, Martínez-Sánchez, Antonio, Bäuerlein, Felix J. B., Guo, Qiang, Arzberger, Thomas, Baumeister, Wolfgang, Dudanova, Irina, Hipp, Mark S., Hartl, F. Ulrich, Fernández-Busnadiego, Rubén

“…The molecular architecture of α-Synuclein (α-Syn) inclusions, pathognomonic of various neurodegenerative disorders, remains unclear. α-Syn inclusions were long…”
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Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography by Rigort, Alexander, Bäuerlein, Felix J. B, Villa, Elizabeth, Eibauer, Matthias, Laugks, Tim, Baumeister, Wolfgang, Plitzko, Jürgen M

“…Cryoelectron tomography provides unprecedented insights into the macromolecular and supramolecular organization of cells in a close-to-living state. However…”
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Automated claustrum segmentation in human brain MRI using deep learning by Li, Hongwei, Menegaux, Aurore, Schmitz‐Koep, Benita, Neubauer, Antonia, Bäuerlein, Felix J. B., Shit, Suprosanna, Sorg, Christian, Menze, Bjoern, Hedderich, Dennis

“…In the last two decades, neuroscience has produced intriguing evidence for a central role of the claustrum in mammalian forebrain structure and function…”
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Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells by Bäuerlein, Felix J.B., Fernández-Busnadiego, Rubén, Baumeister, Wolfgang

“…Neurodegenerative diseases affect the lives of millions of people across the world, being particularly prevalent in the aging population. Despite huge research…”
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Linking the impact of aging on visual short-term memory capacity with changes in the structural connectivity of posterior thalamus to occipital cortices by Menegaux, Aurore, Bäuerlein, Felix J.B., Vania, Aliki, Napiorkowski, Natan, Neitzel, Julia, Ruiz-Rizzo, Adriana L., Müller, Hermann J., Sorg, Christian, Finke, Kathrin

“…Aging impacts both visual short-term memory (vSTM) capacity and thalamo-cortical connectivity. According to the Neural Theory of Visual Attention, vSTM depends…”
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Removing Contamination-Induced Reconstruction Artifacts from Cryo-electron Tomograms by Fernandez, Jose-Jesus, Laugks, Ulrike, Schaffer, Miroslava, Bäuerlein, Felix J.B., Khoshouei, Maryam, Baumeister, Wolfgang, Lucic, Vladan

“…Imaging of fully hydrated, vitrified biological samples by electron tomography yields structural information about cellular protein complexes in situ. Here we…”
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Towards Visual Proteomics at High Resolution by Bäuerlein, Felix J.B., Baumeister, Wolfgang

“…[Display omitted] •Cryo-ET provides high-resolution 3D images of the interior of cells.•Current implementations of cryo-ET do not yet realize the full…”
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In Situ Architecture and Cellular Interactions of PolyQ Inclusions by Bäuerlein, Felix J.B., Saha, Itika, Mishra, Archana, Kalemanov, Maria, Martínez-Sánchez, Antonio, Klein, Rüdiger, Dudanova, Irina, Hipp, Mark S., Hartl, F. Ulrich, Baumeister, Wolfgang, Fernández-Busnadiego, Rubén

“…Expression of many disease-related aggregation-prone proteins results in cytotoxicity and the formation of large intracellular inclusion bodies. To gain…”
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Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices by Jentoft, Ida M A, Bäuerlein, Felix J B, Welp, Luisa M, Cooper, Benjamin H, Petrovic, Arsen, So, Chun, Penir, Sarah Mae, Politi, Antonio Z, Horokhovskyi, Yehor, Takala, Iina, Eckel, Heike, Moltrecht, Rüdiger, Lénárt, Peter, Cavazza, Tommaso, Liepe, Juliane, Brose, Nils, Urlaub, Henning, Fernández-Busnadiego, Rubén, Schuh, Melina

“…Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to…”
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Autophagy preferentially degrades non-fibrillar polyQ aggregates by Zhao, Dorothy Y, Bäuerlein, Felix J B, Saha, Itika, Hartl, F Ulrich, Baumeister, Wolfgang, Wilfling, Florian

“…Aggregation of proteins containing expanded polyglutamine (polyQ) repeats is the cytopathologic hallmark of a group of dominantly inherited neurodegenerative…”
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Structural Basis of Vesicle Formation at the Inner Nuclear Membrane by Hagen, Christoph, Dent, Kyle C., Zeev-Ben-Mordehai, Tzviya, Grange, Michael, Bosse, Jens B., Whittle, Cathy, Klupp, Barbara G., Siebert, C. Alistair, Vasishtan, Daven, Bäuerlein, Felix J.B., Cheleski, Juliana, Werner, Stephan, Guttmann, Peter, Rehbein, Stefan, Henzler, Katja, Demmerle, Justin, Adler, Barbara, Koszinowski, Ulrich, Schermelleh, Lothar, Schneider, Gerd, Enquist, Lynn W., Plitzko, Jürgen M., Mettenleiter, Thomas C., Grünewald, Kay

“…Vesicular nucleo-cytoplasmic transport is becoming recognized as a general cellular mechanism for translocation of large cargoes across the nuclear envelope…”
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Aberrant Claustrum Microstructure in Humans after Premature Birth by Hedderich, Dennis M, Menegaux, Aurore, Li, Hongwei, Schmitz-Koep, Benita, Stämpfli, Philipp, Bäuml, Josef G, Berndt, Maria T, Bäuerlein, Felix J B, Grothe, Michel J, Dyrba, Martin, Avram, Mihai, Boecker, Henning, Daamen, Marcel, Zimmer, Claus, Bartmann, Peter, Wolke, Dieter, Sorg, Christian

“…Abstract Several observations suggest an impact of prematurity on the claustrum. First, the claustrum’s development appears to depend on transient subplate…”
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Micromachining tools and correlative approaches for cellular cryo-electron tomography by Rigort, Alexander, Bäuerlein, Felix J.B., Leis, Andrew, Gruska, Manuela, Hoffmann, Christian, Laugks, Tim, Böhm, Ulrike, Eibauer, Matthias, Gnaegi, Helmut, Baumeister, Wolfgang, Plitzko, Jürgen M.

“…A principal limitation of cryo-transmission electron microscopy performed on cells or tissues is the accessible specimen thickness. This is exacerbated in…”
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Integrative approaches for cellular cryo-electron tomography: correlative imaging and focused ion beam micromachining by Rigort, Alexander, Villa, Elizabeth, Bäuerlein, Felix J B, Engel, Benjamin D, Plitzko, Jürgen M

“…The application of cryo-electron tomography to cells and tissues is commonly referred to as "cellular tomography," and enables visualization of the…”
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Veranderte Zellintegritat des Claustrums bei fruhgeborenen Erwachsenen by Hedderich, Dennis, Berndt, Maria, Bauml, Josef, Reess, Tim, bauerlein, Felix JB, Wohlschlager, Afra, Boecker, Henning, Meng, Chun, Bartmann, Peter, Wolke, Dieter, Zimmer, Claus, Sorg, Christian

“…Hintergrund und Zielsetzung: Das claustrum ist eine struktur des Vorderhirns dessen Funktion weitgehend unbekannt ist und die mit subplate-Neuronen im rahmen…”
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