Search Results - "Bäckman, M."

Kappa Opioid Receptors on Dopaminergic Neurons Are Necessary for Kappa-Mediated Place Aversion by CHEFER, Vladimir I, BÄCKMAN, Cristina M, GIGANTE, Eduardo D, SHIPPENBERG, Toni S

“…Kappa-opioid receptor (KOR) agonists have dysphoric properties in humans and are aversive in rodents. This has been attributed to the activation of KORs within…”
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Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model by Meng, Xianze, Zhang, Yu, Lao, Lixing, Saito, Rikka, Li, Aihui, Bäckman, Cristina M., Berman, Brian M., Ren, Ke, Wei, Pin-Kang, Zhang, Rui-Xin

“…IL-17 is up-regulated in spinal astrocytes during inflammation and facilitates behavioral hyperalgesia through promoting phosphorylation of NR1, the essential…”
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Characterization of a mouse strain expressing Cre recombinase from the 3′ untranslated region of the dopamine transporter locus by Bäckman, Cristina M., Malik, Nasir, Zhang, YaJun, Shan, Lufei, Grinberg, Alex, Hoffer, Barry J., Westphal, Heiner, Tomac, Andreas C.

“…Dopamine (DA) neurotransmission has been implicated in several neurological and psychiatric disorders. The dopamine transporter (DAT) is highly expressed in…”
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Nogo receptor 1 regulates formation of lasting memories by Karlén, Alexandra, Karlsson, Tobias E, Mattsson, Anna, Lundströmer, Karin, Codeluppi, Simone, Pham, Therese M, Bäckman, Cristina M, Ögren, Sven Ove, Åberg, Elin, Hoffman, Alexander F, Sherling, Michael A, Lupica, Carl R, Hoffer, Barry J, Spenger, Christian, Josephson, Anna, Brené, Stefan, Olson, Lars

“…Formation of lasting memories is believed to rely on structural alterations at the synaptic level. We had found that increased neuronal activity down-regulates…”
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NMDA receptors on non-dopaminergic neurons in the VTA support cocaine sensitization by Luo, Yu, Good, Cameron H, Diaz-Ruiz, Oscar, Zhang, YaJun, Hoffman, Alexander F, Shan, Lufei, Kuang, Serena Y, Malik, Nasir, Chefer, Vladimir I, Tomac, Andreas C, Lupica, Carl R, Bäckman, Cristina M

“…The initiation of behavioral sensitization to cocaine and other psychomotor stimulants is thought to reflect N-methyl-D-aspartate receptor (NMDAR)-mediated…”
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Gene expression patterns in mouse cortical penumbra after focal ischemic brain injury and reperfusion by Sarabi, Arezou S., Shen, Hui, Wang, Yun, Hoffer, Barry J., Bäckman, Cristina M.

“…Ischemic stress in the brain causes acute and massive cell death in the targeted core area followed by a second phase of damage in the neighboring penumbra…”
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PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice by YAJUN ZHANG, GRANHOLM, Ann-Charlotte, BÄCKMAN, Cristina M, HUH, Kyounghee, LUFEI SHAN, DIAZ-RUIZ, Oscar, MALIK, Nasir, OLSON, Lars, HOFFER, Barry J, LUPICA, Carl R, HOFFMAN, Alexander F

“…Clinical trials in Parkinson's disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host…”
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Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease by Good, Cameron H., Hoffman, Alexander F., Hoffer, Barry J., Chefer, Vladimir I., Shippenberg, Toni S., Bäckman, Cristina M., Larsson, Nils‐Göran, Olson, Lars, Gellhaar, Sandra, Galter, Dagmar, Lupica, Carl R.

“…ABSTRACT Parkinson's disease (PD) involves progressive loss of nigrostriatal dopamine (DA) neurons over an extended period of time. Mitochondrial damage may…”
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Identification of a Human Nuclear Receptor Defines a New Signaling Pathway for CYP3A Induction by Bertilsson, Goran, Heidrich, Jessica, Svensson, Kristian, Asman, Michael, Jendeberg, Lena, Sydow-Backman, Mona, Ohlsson, Rolf, Postlind, Hans, Blomquist, Patrik, Berkenstam, Anders

“…Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene expression of key metabolic enzymes…”
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Effect of self-managed lifestyle treatment on glycemic control in patients with type 2 diabetes by Dwibedi, Chinmay, Mellergård, Emelia, Gyllensten, Amaru Cuba, Nilsson, Kristoffer, Axelsson, Annika S., Bäckman, Malin, Sahlgren, Magnus, Friend, Stephen H., Persson, Sofie, Franzén, Stefan, Abrahamsson, Birgitta, Carlsson, Katarina Steen, Rosengren, Anders H.

“…The lack of effective, scalable solutions for lifestyle treatment is a global clinical problem, causing severe morbidity and mortality. We developed a method…”
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Early post-treatment with 9-cis retinoic acid reduces neurodegeneration of dopaminergic neurons in a rat model of Parkinson's disease by Yin, Lian-Hu, Shen, Hui, Diaz-Ruiz, Oscar, Bäckman, Cristina M, Bae, Eunkyung, Yu, Seong-Jin, Wang, Yun

“…Retinoic acid (RA) is a biologically active derivative of vitamin A. Previous studies have demonstrated that RA has protective effects against damage caused by…”
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l -Dopa induced dyskinesias in Parkinsonian mice: Disease severity or l -Dopa history by Shan, Lufei, Diaz, Oscar, Zhang, Yajun, Ladenheim, Bruce, Cadet, Jean-Lud, Chiang, Yung-Hsiao, Olson, Lars, Hoffer, Barry J, Bäckman, Cristina M

“…Abstract In Parkinson’s disease, the efficacy of l -Dopa treatment changes over time, as dyskinesias emerge with previously beneficial doses. Using MitoPark…”
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Psychiatric symptoms of children and adolescents with juvenile neuronal ceroid lipofuscinosis by Bäckman, M. L., Santavuori, P. R., Åberg, L. E., Aronen, E. T.

“…Background  Juvenile neuronal ceroid lipofuscinosis (JNCL) is one of the most common neurodegenerative disorders in childhood and adolescence. The clinical…”
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Effect of a novel non-thiazolidinedione peroxisome proliferator-activated receptor α/γ agonist on glucose uptake by HU, X, FENG, Y, LIU, X, ZHAO, X.-F, YU, J.-H, YANG, Y.-S, SYDOW-BACKMAN, M, HORLING, J, ZIERATH, J. R, LENG, Y

“…The effect of the benzopyran derivative T33, a novel non-thiazolidinedione agent, was studied on peroxisome proliferator-activated receptors (PPARs), insulin…”
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Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons by Freed, William J, Chen, Jia, Bäckman, Cristina M, Schwartz, Catherine M, Vazin, Tandis, Cai, Jingli, Spivak, Charles E, Lupica, Carl R, Rao, Mahendra S, Zeng, Xianmin

“…We initiated differentiation of human embryonic stem cells (hESCs) into dopamine neurons, obtained a purified population of neuronal precursor cells by cell…”
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Identification of lignans by liquid chromatography-electrospray ionization ion-trap mass spectrometry by Eklund, Patrik C, Backman, M. Josefin, Kronberg, Leif Å, Smeds, Annika I, Sjöholm, Rainer E

“…The fragmentation pattern of 30 compounds belonging to different classes of the lignan family was studied by liquid chromatography-electrospray ionization…”
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Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features by Pellinen, Teijo, Paavolainen, Lassi, Martín-Bernabé, Alfonso, Papatella Araujo, Renata, Strell, Carina, Mezheyeuski, Artur, Backman, Max, La Fleur, Linnea, Brück, Oscar, Sjölund, Jonas, Holmberg, Erik, Välimäki, Katja, Brunnström, Hans, Botling, Johan, Moreno-Ruiz, Pablo, Kallioniemi, Olli, Micke, Patrick, Östman, Arne

“…Cancer-associated fibroblasts (CAFs) are molecularly heterogeneous mesenchymal cells that interact with malignant cells and immune cells and confer anti- and…”
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Molecular dynamics simulations of swift heavy ion induced defect recovery in SiC by Backman, M., Toulemonde, M., Pakarinen, O.H., Juslin, N., Djurabekova, F., Nordlund, K., Debelle, A., Weber, W.J.

“…► Swift heavy ions in SiC studied in molecular dynamics simulations. ► Heating due to swift heavy ions modeled by the inelastic thermal spike model. ►…”
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Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson's disease by Farrand, Ariana Q, Gregory, Rebecca A, Bäckman, Cristina M, Helke, Kristi L, Boger, Heather A

“…Abstract Mitochondrial dysfunction has been implicated in the degeneration of dopamine (DA) neurons in Parkinson's disease (PD). In addition, animal models of…”
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Willingness to try new foods as predicted by social representations and attitude and trait scales by Bäckström, A., Pirttilä-Backman, A.-M., Tuorila, H.

“…The structure and predictive ability of social representation of new foods were investigated and compared with instruments measuring relevant attitudes and…”
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