Search Results - "Bárcena, J Antonio"

Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer by Rodríguez-Hernández, María A., de la Cruz-Ojeda, P, López-Grueso, Mª José, Navarro-Villarán, Elena, Requejo-Aguilar, Raquel, Castejón-Vega, Beatriz, Negrete, María, Gallego, Paloma, Vega-Ochoa, Álvaro, Victor, Victor M., Cordero, Mario D., Del Campo, José A., Bárcena, J. Antonio, Padilla, C. Alicia, Muntané, Jordi

“…Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals, evasion of apoptosis, cellular stress, and sustained…”
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NOX1 and PRDX6 synergistically support migration and invasiveness of hepatocellular carcinoma cells through enhanced NADPH oxidase activity by Lagal, Daniel J., Bárcena, J. Antonio, Requejo-Aguilar, Raquel, Padilla, C. Alicia, Leto, Thomas L.

“…•NOX1 activity promotes hallmarks of metastasis including cell migration and invasion.•PRDX6 contributes to these pro-metastatic pathways through direct…”
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Loss of PRDX6 Aborts Proliferative and Migratory Signaling in Hepatocarcinoma Cell Lines by Lagal, Daniel J, López-Grueso, María J, Pedrajas, José R, Leto, Thomas L, Bárcena, J Antonio, Requejo-Aguilar, Raquel, Padilla, C Alicia

“…Peroxiredoxin 6 (PRDX6), the only mammalian 1-Cys member of the peroxiredoxin family, has peroxidase, phospholipase A2 (PLA2), and lysophosphatidylcholine…”
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Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells by González, Raúl, López-Grueso, M José, Muntané, Jordi, Bárcena, J Antonio, Padilla, C Alicia

“…Nitric oxide (NO) plays relevant roles in signal transduction in physiopathology and its effects are dependent on several environmental factors. NO has both…”
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A surface protein of Streptococcus suis serotype 2 identified by proteomics protects mice against infection by Mandanici, Francesca, Gómez-Gascón, Lidia, Garibaldi, Manuela, Olaya-Abril, Alfonso, Luque, Inmaculada, Tarradas, Carmen, Mancuso, Giuseppe, Papasergi, Salvatore, Bárcena, J. Antonio, Teti, Giuseppe, Beninati, Concetta, Rodríguez-Ortega, Manuel J.

“…Streptococcus suis serotype 2 is a major Gram-positive swine pathogen, causing also zoonoses. We describe here the immunoprotective activity in an in vivo…”
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One Single In-frame AUG Codon Is Responsible for a Diversity of Subcellular Localizations of Glutaredoxin 2 in Saccharomyces cerevisiae by Porras, Pablo, Padilla, C. Alicia, Krayl, Martin, Voos, Wolfgang, Bárcena, J. Antonio

“…Glutaredoxins belong to a family of small proteins with glutathione-dependent disulfide oxidoreductase activity involved in cellular defense against oxidative…”
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Structure and function of yeast glutaredoxin 2 depend on postranslational processing and are related to subcellular distribution by Porras, Pablo, McDonagh, Brian, Pedrajas, Jose Rafael, Bárcena, J. Antonio, Padilla, C. Alicia

“…We have previously shown that glutaredoxin 2 (Grx2) from Saccharomyces cerevisiae localizes at 3 different subcellular compartments, cytosol, mitochondrial…”
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Redox Regulation Of Metabolic And Signaling Pathways By Thioredoxin And Glutaredoxin In Nitric Oxide Treated Hepatoblastoma Cells by Peña, C Alicia Padilla, González, Raúl, López-Grueso, María J, Antonio Bárcena, J

“…NO has an antiproliferative action on HepG2 cells and Thioredoxin (Trx) and Glutaredoxin (Grx) have denitrosilase and deglutathionylase activities. To…”
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Redox regulation of c‐Jun DNA binding by reversible S‐glutathiolation by Klatt, Peter, Molina, Estela Pineda, Lacoba, Mario Garcia, Padilla, C. Alicia, Martínez‐Galisteo, Emilia, Barcena, J., Lamas, Santiago

“…ABSTRACTRedox control of the transcription factor c‐Jun maps to a single cysteine in its DNA binding domain. However, the nature of the oxidized state of this…”
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Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments by Pedrajas, José R, Porras, Pablo, Martínez-Galisteo, Emilia, Padilla, C Alicia, Miranda-Vizuete, Antonio, Bárcena, J Antonio

“…Glutaredoxin (Grx)2 from Saccharomyces cerevisiae is a member of the two-cysteine (dithiol) subfamily of Grxs involved in the defence against oxidative stress…”
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Glutaredoxins catalyze the reduction of glutathione by dihydrolipoamide with high efficiency by Porras, Pablo, Pedrajas, José R., Martı́nez-Galisteo, Emilia, Alicia Padilla, C., Johansson, Catrine, Holmgren, Arne, Antonio Bárcena, J.

“…Glutaredoxins (Grx) are small (≈12 kDa) proteins which catalyze thiol disulfide oxidoreductions involving glutathione (GSH) and disulfides in proteins or small…”
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NADPH and oxidized thioredoxin mediate redox interconversion of calf-liver and Escherichia coli thioredoxin reductase by MARTINEZ-GALISTEO, E, GARCIA-ALFONSO, C, PADILLA, C. A, BARCENA, J. A, LOPEZ-BAREA, J

“…The activity of pure calf-liver and Escherichia coli thioredoxin reductases decreased drastically in the presence of NADPH or NADH, while NADP+, NAD+ and…”
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One single in-frame AUG codon is responsible for a diversity of subcellular localizations of glutaredoxin 2 in Saccharomyces cerevisiae. VOLUME 281 (2006) PAGES 16551-16562 by Porras, Pablo, Padilla, C. Alicia, Krayl, Martin, Voos, Wolfgang, Bárcena, J. Antonio

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Purification from Placenta, Amino Acid Sequence, Structure Comparisons and cDNA Cloning of Human Glutaredoxin by Padilla, C. Alicia, Martínez‐Galisteo, Emilia, Bárcena, J. Antonio, Spyrou, Giannis, Holmgren, Arne

“…Glutaredoxin is generally a glutathione‐dependent hydrogen donor for ribonucleotide reductase and also catalyses general glutathione…”
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Characterization of mammalian thioredoxin reductase, thioredoxin and glutaredoxin by immunochemical methods by Martinez-Galisteo, Emilia, Padilla, C.Alicia, Holmgren, Arne, Bárcena, J.Antonio

“…Specific polyclonal antibodies towards the oxidized form of bovine thioredoxin reductase (TR) have been obtained in rabbits, and purified. The antigenicity was…”
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Immunolocalization of thioredoxin and glutaredoxin in mammalian hypophysis by Padilla, C A, Martínez-Galisteo, E, López-Barea, J, Holmgren, A, Bárcena, J A

“…Thioredoxin (TRX) and glutaredoxin (GRX) are two small proteins catalyzing thiol-disulfide oxidoreductions. A role of both proteins in secretory processes has…”
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HPLC isoenzyme patterns of glutathione transferase from marine fishes with different levels of pollution by Pascual, P, Martínez-Lara, E, Toribio, F, López-Barea, J, Bárcena, J A

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Topological relationships between porcine anterior pituitary hormones and the thioredoxin and glutaredoxin systems by Padilla, C A, Martínez-Galisteo, E, Bárcena, J A

“…Thioredoxin (TRX) and glutaredoxin (GRX) had previously been localized in folliculo-stellatae (FS) cells and in only a fraction of glandular cells of the…”
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Horse-liver glutathione reductase: purification and characterization by García-Alfonso, C, Martínez-Galisteo, E, Llobell, A, Bárcena, J A, López-Barea, J

“…1. Purification of horse-liver glutathione reductase was obtained by affinity chromatography on N6-(6-aminohexyl)-adenosine-1'5'-bisphosphate Sepharose…”
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Regulation of horse-liver glutathione reductase by García-Alfonso, C, Martínez-Galisteo, E, Llobell, A, Bárcena, J A, López-Barea, J

“…1. The enzyme was rapidly inactivated by NAD(P)H, GSH, dithionite or borohydride, while activity increased in the presence of NAD(P)+ or GSSG. NADH was more…”
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